Patents by Inventor Rachel S. Kohn

Rachel S. Kohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6455526
    Abstract: A new class of biodegradable pharmaceutical compositions useful as sustained release medicamentous compositions, including methods of making and methods of using these compositions, are described and claimed. The method of making these compositions include the steps of: a) dry mixing of a pharmaceutically active molecule with a biodegradable polymer; b) melt extruding the mixture to form a solid solution of the active molecule in the polymer; and c) pulverizing the solid solution to form microparticles such that they can be formed into injectable formulations. Preferred embodiments include pharmaceutical compositions of polylactide-co-glycolide and (+)-&agr;-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol (active ingredient) and a method for its formation. These compositions release the active ingredient at a steady rate over a period of days to weeks.
    Type: Grant
    Filed: December 7, 1999
    Date of Patent: September 24, 2002
    Assignee: Aventis Pharmaceuticals, Inc.
    Inventors: Rachel S. Kohn, Stephen J. Hanley, Stephen J. Comiskey
  • Patent number: 5614309
    Abstract: A polypropylene or polyethylene film or fiber coated with a maleic-acid grafted polypropylene or polyethylene copolymer layer over which is coated a layer of selective polymer. The copolymer securely bonds the selective polymer to the film or fiber. These fibers and films can be used in fluid separation membranes.
    Type: Grant
    Filed: May 19, 1992
    Date of Patent: March 25, 1997
    Assignee: Hoechst Celanese Corp.
    Inventors: Tai-Shung Chung, Edward R. Kafchinski, Rachel S. Kohn, Frank J. Onorato, Jr.
  • Patent number: 5320754
    Abstract: A novel method for making a composite separation membrane, and the product of that method. This novel method includes applying one or more perfluoroethers to the surface of a microporous fiber or film made of a polymer such as PAN, and subsequently coating that fiber or film surface with a layer of selective material. This method provides a more permeable composite membrane than would be obtained by coating a fiber or film that had not been pre-wetted with perfluoroether.
    Type: Grant
    Filed: December 18, 1992
    Date of Patent: June 14, 1994
    Assignee: Hoechst Celanese Corp.
    Inventors: Rachel S. Kohn, Edward R. Kafchinski, Tai-Shung Chung, Brenda A. Bembry-Ross
  • Patent number: 5232757
    Abstract: This invention provides a superior process for optical information storage by providing a mixture of azaannulene compounds in the recording layer. The recording layer exhibits large positive contrast in the recorded areas upon recording with laser radiation. The positive contrast is surprisingly larger than the positive contrasts exhibited by recording layers made from the individual azaannulenes included in the mixture, and because of this large positive contrast the sensitivity of the medium is high and consequently low laser powers are sufficient to effect the recording.
    Type: Grant
    Filed: December 6, 1991
    Date of Patent: August 3, 1993
    Assignee: Hoechst Celanese Corp.
    Inventors: Palaiyur S. Kalyanaraman, Harris A. Goldberg, Rachel S. Kohn
  • Patent number: 5074891
    Abstract: An improved method of gas separation and novel polyimide membranes are disclosed and claimed. Membranes in accordance with the present invention include the condensation product of fluorinated diamines such as 2,2'-bis(3-aminophenyl)hexafluoropropane, 2,2'-bis(4-aminophenyl)hexafluoropropane and 2-(3-aminophenyl)-2'-(4-aminophenyl)hexafluoropropane with aromatic dianhydrides such as 3,3', 4,4' benzophenone tetracarboxylic acid dianhydride.
    Type: Grant
    Filed: July 27, 1989
    Date of Patent: December 24, 1991
    Assignee: Hoechst Celanese Corp.
    Inventors: Rachel S. Kohn, Sidney R. Jones, Werner H. Mueller
  • Patent number: 5055116
    Abstract: The present invention provides for gas separation membranes which are engineered to have specific gas transport properties based on the blending of certain polymers. In preferred embodiments, the blended polymers are polyimides which have different molecular structures and different gas transport properties. Despite these differences, however, the polymers are completely miscible and can be effectively utilized to prepare gas separation membranes having specifically tailored properties.
    Type: Grant
    Filed: April 3, 1990
    Date of Patent: October 8, 1991
    Assignee: Hoechst Celanese Corp.
    Inventors: Rachel S. Kohn, Maria R. Coleman, Tai-Shung Chung
  • Patent number: 5045440
    Abstract: Provided is a method for stabilizing an optical information medium by incorporating an effective amount of a specific nitrogen containing compound into the medium. The specific nitrogen containing compounds are poly(2-vinyl pyridine), poly(4-vinyl pyridine), pentaethylene hexamine and acridine orange base. Incorporation of one of the nitrogen compounds into the optical information medium prolongs the useful life of the medium.
    Type: Grant
    Filed: February 7, 1990
    Date of Patent: September 3, 1991
    Assignee: Hoechst Celanese Corp.
    Inventors: Frank J. Onorato, David E. Nikles, Rachel S. Kohn, Susan C. Castles, Harris A. Goldberg
  • Patent number: 4978573
    Abstract: Disclosed herein are free-standing, pinhole-free, ultrathin polyimide films having thickness of about 400 angstroms or less and a process to prepare them. The films find particular utility in separatory applications.
    Type: Grant
    Filed: March 15, 1990
    Date of Patent: December 18, 1990
    Assignee: Hoechst Celanese Corp.
    Inventor: Rachel S. Kohn
  • Patent number: 4929405
    Abstract: Disclosed herein are free-standing, pinhole-free, ultrathin polymide films having thicknesses of about 400 angstroms or less and a process to prepare them. The films find particular utility in separatory applications.
    Type: Grant
    Filed: May 22, 1989
    Date of Patent: May 29, 1990
    Assignee: Hoechst Celanese Corp.
    Inventor: Rachel S. Kohn
  • Patent number: 4910083
    Abstract: Disclosed herein are free-standing, pinhole-free, ultrathin, polyarylate films having thicknesses of about 400 angstroms or less and a process to prepare them. The films find particular utility in separatory applications.
    Type: Grant
    Filed: January 29, 1988
    Date of Patent: March 20, 1990
    Assignee: Hoechst Celanese Corp.
    Inventor: Rachel S. Kohn
  • Patent number: 4910082
    Abstract: Disclosed herein are free-standing, pinhole-free, ultrathin, polyphenylene oxide films having thicknesses of about 400 angstroms or less and a process for preparing them. The films find particular utility in separatory applications.
    Type: Grant
    Filed: January 29, 1988
    Date of Patent: March 20, 1990
    Assignee: Hoechst Celanese Corp.
    Inventor: Rachel S. Kohn
  • Patent number: 4908266
    Abstract: Disclosed herein are pinhole-free, ultrathin, free-standing cellulose ester films having thicknesses of 400 angstroms or less and a process to prepare them. The films find particular utility in separatory applications.
    Type: Grant
    Filed: January 29, 1988
    Date of Patent: March 13, 1990
    Assignee: Hoechst Celanese Corp.
    Inventor: Rachel S. Kohn
  • Patent number: 4908267
    Abstract: Disclosed herein are free-standing, pinhole-free, ultrathin polyether sulfone films having thicknesses of about 400 angstroms or less and a process for preparing them. The films find particular utility in separatory applications.
    Type: Grant
    Filed: January 29, 1988
    Date of Patent: March 13, 1990
    Assignee: Hoechst Celanese Corp.
    Inventor: Rachel S. Kohn
  • Patent number: 4900621
    Abstract: Disclosed herein are free-standing, pinhole-free, ultrathin, blended, cellulose nitrate films having thicknesses of about 400 angstroms or less and a process to prepare them. The films find particular utility in separatory applications.
    Type: Grant
    Filed: January 29, 1988
    Date of Patent: February 13, 1990
    Assignee: Hoechst Celanese Corporation
    Inventor: Rachel S. Kohn
  • Patent number: 4900623
    Abstract: Disclosed herein are pinhole-free, ultrathin, polymethylmethacrylate films having thicknesses of about 400 angstroms or less and a process to prepare them. The films find particular utility in separatory applications.
    Type: Grant
    Filed: April 14, 1988
    Date of Patent: February 13, 1990
    Assignee: Hoechst Celanese Corporation
    Inventor: Rachel S. Kohn
  • Patent number: 4880699
    Abstract: Disclosed herein are free-standing, pinhole-free, ultrathin polyimide films having thicknesses of about 400 angstroms or less and a process to prepare them. The films find particular utility in separatory applications.
    Type: Grant
    Filed: April 17, 1989
    Date of Patent: November 14, 1989
    Assignee: Hoechst Celanese Corporation
    Inventor: Rachel S. Kohn
  • Patent number: 4776999
    Abstract: Disclosed herein are free-standing, pinhole-free, ultrathin polyether sulfone films having thicknesses of about 400 angstroms or less and a process for preparing them. The films find particular utility in separatory applications.
    Type: Grant
    Filed: October 10, 1986
    Date of Patent: October 11, 1988
    Assignee: Hoechst Celanese Corporation
    Inventor: Rachel S. Kohn
  • Patent number: 4765939
    Abstract: A process to prepare pinhole-free, ultrathin, polymethylmethacrylate films having thicknesses of about 400 angstroms or less. The films are prepared by dissolving a polymethylmethacrylate polymer in a mixture of solvents to form a casting solution and then casting the solution upon water to form a free-standing film. The films find particular utility in separatory applications.
    Type: Grant
    Filed: October 10, 1986
    Date of Patent: August 23, 1988
    Assignee: Hoechst Celanese Corporation
    Inventor: Rachel S. Kohn
  • Patent number: 4752339
    Abstract: This invention provides a process for preparing a viscoelastic aqueous solution which contains divinylsulfone-crosslinked polygalactomannan gum that is formed in situ.An invention thixotropic aqueous medium is characterized by excellent heat/shear stability and high tolerance to the presence of inorganic salts.A unique property of an invention thixotropic aqueous medium is a time-dependent gradual restoration of high viscosity after cessation of high shear deformation.
    Type: Grant
    Filed: October 31, 1983
    Date of Patent: June 21, 1988
    Assignee: Hi-Tek Polymers, Inc.
    Inventor: Rachel S. Kohn
  • Patent number: 4746472
    Abstract: Disclosed herein are free-standing, pinhole-free, ultrathin, polyarylate films having thicknesses of about 400 angstroms or less and a process to prepare them. The films find particular utility in separatory applications.
    Type: Grant
    Filed: October 10, 1986
    Date of Patent: May 24, 1988
    Assignee: Hoechst Celanese Corporation
    Inventor: Rachel S. Kohn