Patents by Inventor Rachel Theodora Pijls

Rachel Theodora Pijls has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Coiled wire for the controlled release of drugs to the eye
    Patent number: 8109913
    Abstract: This invention is in the area of medical devices, in particular in the area of medical devices for drug delivery, more in particular for controlled release of drugs to the eye. Delivery of drugs to the anterior side of the eye is routinely done with eye drops, but this method results in low bioavailability and low patient compliance. Devices that address these problems have been described for the delivery of drugs to the eye. One of such devices, called the OphthaCoil, consists of a thin metallic wire, which is coiled and carries a drug-loaded adherent hydrogel coating on its surface. Surprisingly it has now been found that the drug loading capacity can be dramatically increased by filling the lumen of the coil with micro-particles such as microspheres that contain the drug of choice.
    Type: Grant
    Filed: June 30, 2006
    Date of Patent: February 7, 2012
    Assignee: DSM IP Assets B.V.
    Inventors: Aylvin Jorge Angelo Athanasius Dias, Levinus Hendrik Koole, Rachel Theodora Pijls
  • COILED WIRE FOR THE CONTROLLED RELEASE OF DRUGS TO THE EYE
    Publication number: 20090143747
    Abstract: This invention is in the area of medical devices, in particular in the area of medical devices for drug delivery, more in particular for controlled release of drugs to the eye. Delivery of drugs to the anterior side of the eye is routinely done with eye drops, but this method results in low bioavailability and low patient compliance. Devices that address these problems have been described for the delivery of drugs to the eye. One of such devices, called the OphthaCoil, consists of a thin metallic wire, which is coiled and carries a drug-loaded adherent hydrogel coating on its surface. Surprisingly it has now been found that the drug loading capacity can be dramatically increased by filling the lumen of the coil with micro-particles such as microspheres that contain the drug of choice.
    Type: Application
    Filed: June 30, 2006
    Publication date: June 4, 2009
    Inventors: Aylvin Jorge Angelo Athanasius Dias, Levinus Hendrik Koole, Rachel Theodora Pijls