Abstract: A gap blocking system includes a loading platform having a gap separating a first portion of the loading platform from a second portion of the loading platform. A ride vehicle is coupled to a transport extending through the gap. A guardrail assembly having a plurality of guardrail units is coupled to the first portion, where the guardrail units are configured to transition between a first position and a second position. The guardrail units are configured to block access to the gap when in the first position. The ride vehicle includes an engagement feature configured to interface with an individual guardrail unit of the guardrail units to selectively transition the individual guardrail unit from the first position to the second position. The individual guardrail unit is configured to permit the ride vehicle to occupy a guest-accessible position adjacent to or on the loading platform in the second position.

Abstract: Embodiments of the disclosure relate generally to formulations, methods, kits, and dosage forms for improved stability comprising at least two active ingredients, AMD3100, or similar stem cell mobilizer, and Tacrolimus, or FK506 derivative or analog, and one or more excipients. The formulations may be administered as a single dose subcutaneous injection. The formulations may be useful in treating various diseases, disorders or injuries.

Abstract: A breathing assistance apparatus has a housing with an engagement feature and an electrical component in the housing and a removable component. The electrical component has a receptacle. The removable component has an electrical connector that is a close or tight fit in the receptacle of the electrical component to assist with holding the removable component in connection with the electrical component. The removable component has a tab with a terminal end portion that can be flexed relative to the rest of the removable component. An engagement feature is provided on the terminal end portion of the tab and engages with the engagement feature of the housing to inhibit disconnection of the removable component from the housing in the absence of actuating the terminal end portion of the removable component to flex the tab.

Abstract: A composition comprises: a base oil; an additive; and a drug. The additive has segments which are conjugated, e.g. covalently linked, together. A first segment facilitates solubility in the base oil, whereas a second segment facilitates drug solubility and/or modifies drug release or other behaviour. The first segment may for example comprise a poly(dimethylsiloxane)-containing moiety. The second segment may for example resemble a drug molecule. The composition may for example be used as a tamponade or as a component for a tamponade administered to the eye.

Abstract: A charging station includes a charging head and a plurality of electrical connectors. The charging head is slidable along a track and rotatable along an axis. The plurality of electrical connectors is secured to the charging head and is disposed radially about the axis. Each of the electrical connectors have a different profile and are configured to engage an electrical port of an electric vehicle having a matching profile to charge the battery of the electric vehicle. The charging head is configured to slide along the track and rotate along the axis to align each of the electrical connectors with a corresponding electrical port. Each of the electrical connectors is configured to advance from and retract to the charging head to engage and disengage the corresponding electrical port.

Abstract: A composition comprises: a base oil; an additive comprising a copolymer comprising hydrophobic and hydrophilic units; and a drug. The copolymer may for example have a comb structure in which the hydrophobic units and hydrophilic units are pendant chains on a backbone of the copolymer. The hydrophobic units and hydrophilic units may for example comprise polydimethylsiloxane moieties and ethylene glycol residues respectively. The composition may for example be used as a tamponade or as a component for a tamponade administered to the eye. The invention is useful for solubilising and/or releasing drugs.

Abstract: A vehicle includes a body and a charging pad. The body defines first and second wheel wells on opposing lateral sides of the body. The body defines a cavity along a bottom surface of the body between the wheel wells and a rear end of the vehicle. The charging pad is disposed within the cavity such that the charging pad spans a distance between the first and second wheel wells. The charging pad has a secondary coil disposed therein. The secondary coil is configured to receive electrical power from a primary coil of a charging station via induction to recharge a vehicle battery.

Abstract: A charging station includes a charging head and a plurality of electrical connectors. The charging head is slidable along a track and rotatable along an axis. The plurality of electrical connectors is secured to the charging head and is disposed radially about the axis. Each of the electrical connectors have a different profile and are configured to engage an electrical port of an electric vehicle having a matching profile to charge the battery of the electric vehicle. The charging head is configured to slide along the track and rotate along the axis to align each of the electrical connectors with a corresponding electrical port. Each of the electrical connectors is configured to advance from and retract to the charging head to engage and disengage the corresponding electrical port.

Abstract: A vehicle includes a body and a charging pad. The body defines first and second wheel wells on opposing lateral sides of the body. The body defines a cavity along a bottom surface of the body between the wheel wells and a rear end of the vehicle. The charging pad is disposed within the cavity such that the charging pad spans a distance between the first and second wheel wells. The charging pad has a secondary coil disposed therein. The secondary coil is configured to receive electrical power from a primary coil of a charging station via induction to recharge a vehicle battery.

Abstract: An adapter plug for a charging port of an electric vehicle includes a housing, a first electrical connector, and a second electrical connector. The housing has circuitry disposed therein. The first electrical connector is integral to the housing, faces a first direction, and has a first profile. The first profile is configured to mate with the charging port and connect the circuitry to the charging port. The second electrical connector is integral to the housing, faces a second direction opposing the first direction, and has a second profile. The second profile matches the charging port. The second profiled is configured to mate with a connector head of a charging station and connect the circuitry to the connector head.

Abstract: A system and a computer-implemented method are disclosed. The method comprises the steps of: receiving, from a golfer mobile device, a request to conduct a round of golf, the request comprising round information and identification of a validator mobile device, receiving, from the validator mobile device, confirmation of validator status, receiving, from the golfer mobile device, score data and location data of the golfer mobile device. The method further comprises receiving, from the validator mobile device, location data of the validator mobile device, determining whether the received score data is valid by comparing the location data of the golfer mobile device to the location data of the validator mobile device, and determining and recording a score based on the score data for the golfer if the received score data is determined to be valid.

Abstract: A composition comprises: a base oil; an additive comprising a copolymer comprising hydrophobic and hydrophilic units; and a drug. The copolymer may for example have a comb structure in which the hydrophobic units and hydrophilic units are pendant chains on a backbone of the copolymer. The hydrophobic units and hydrophilic units may for example comprise polydimethylsiloxane moieties and ethylene glycol residues respectively. The composition may for example be used as a tamponade or as a component for a tamponade administered to the eye. The invention is useful for solubilising and/or releasing drugs.

Abstract: A composition comprises: a base oil; an additive; and a drug. The additive has segments which are conjugated, e.g. covalently linked, together. A first segment facilitates solubility in the base oil, whereas a second segment facilitates drug solubility and/or modifies drug release or other behaviour. The first segment may for example comprise a poly(dimethylsiloxane)-containing moiety. The second segment may for example resemble a drug molecule. The composition may for example be used as a tamponade or as a component for a tamponade administered to the eye.

Abstract: Among other things, there is disclosed a biopsy needle system in which the needle is capable of obtaining more than one length of sample. Generally, the needle includes an inner stylet, an outer cannula, and a handle connected to the stylet and cannula. The stylet has a notch that is extendable from the cannula to accommodate a tissue sample. An insert member is provided for attachment to the handle to make the amount of exposed notch smaller. Consequently, when the insert member is not attached to the handle, the needle can obtain a larger sample of tissue, and when the insert member is attached to the handle, the needle can obtain a smaller sample of tissue.

Abstract: Among other things, there is disclosed a biopsy needle system in which the needle is capable of obtaining more than one length of sample. Generally, the needle includes an inner stylet, an outer cannula, and a handle connected to the stylet and cannula. The stylet has a notch that is extendable from the cannula to accommodate a tissue sample. An insert member is provided for attachment to the handle to make the amount of exposed notch smaller. Consequently, when the insert member is not attached to the handle, the needle can obtain a larger sample of tissue, and when the insert member is attached to the handle, the needle can obtain a smaller sample of tissue.

Abstract: The present invention relates to novel substrates, to methods of making them and to uses therefor. The substrates of the invention comprise a base portion and a surface layer covering at least part of the base portion, with a binding layer provided therebetween. The surface layer provides, on at least a part of the substrate, topographical features having at least one nano scale dimension. These topographical features are adapted to inhibit cell or tissue growth thereon and/or therebetween.