Patents by Inventor Radina Kostadinova-Angelova

Radina Kostadinova-Angelova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screenable Liver Disease Models and Methods
    Publication number: 20240043808
    Abstract: An in vitro testing platform for the study of metabolic liver disease and related therapeutic strategies, composed of an artificial spheroidal microtissue comprising at least hepatocytes and hepatic stellate cells, and at least one type of hepatic inflammatory cells and further medium and reagents capable to establish and simulate different stages of metabolic liver disease and their progression and testing preventive and therapeutic strategies by pharmacological and/or dietary interventions.
    Type: Application
    Filed: August 7, 2023
    Publication date: February 8, 2024
    Inventors: Simon Messner, Jens M Kelm, Radina Kostadinova-Angelova, Wolfgang Moritz
  • SCREENABLE LIVER DISEASE MODELS AND METHODS
    Publication number: 20190316093
    Abstract: The present invention relates to an in vitro testing platform for the study of metabolic liver disease and related therapeutic strategies, composed of an artificial spheroidal microtissue comprising at least hepatocytes and hepatic stellate cells, and at least one type of hepatic inflammatory cells and further medium and reagents capable to establish and simulate different stages of metabolic liver disease and their progression and testing preventive and therapeutic strategies by pharmacological and/or dietary interventions.
    Type: Application
    Filed: December 27, 2017
    Publication date: October 17, 2019
    Inventors: Simon Messner, Jens M. Kelm, Radina Kostadinova-Angelova, Wolfgang Moritz