Patents by Inventor Radoslaw Laufer

Radoslaw Laufer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N3-SUBSTITUTED IMIDAZOPYRIDINE C-KIT INHIBITORS
    Publication number: 20080221153
    Abstract: Compounds represented by Formula (I): or a pharmaceutically acceptable salt or N-oxide thereof, are useful in the treatment of cancer.
    Type: Application
    Filed: August 16, 2004
    Publication date: September 11, 2008
    Inventors: Arlindo Castelhano, Andrew Crew, Han-Qing Dong, Radoslaw Laufer, An-Hu Li, Li Qiu, Colin Sambrook Smith, Tao Zhang
  • N-substituted benzimidazoyl c-Kit inhibitors and combinatorial benzimidazole library
    Patent number: 7419995
    Abstract: Compounds represented by Formula (I): or a pharmaceutically acceptable salt or N-oxide thereof, are useful in the treatment of tumors. Combinatorial libraries composed of compounds represented by Formula (I) or benzimidazole compounds represented by Formula (II): are useful in providing compounds to assay for such therapeutically useful compounds.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: September 2, 2008
    Assignee: OSI Pharmaceuticals, Inc.
    Inventors: Andrew Philip Crew, Matthew Cox, Radoslaw Laufer, Neil Anthony Pegg, Colin Peter Sambrook Smith, Yingchuan Sun, Robin David Wilkes, Jonathan Williams
  • N-phenylbenzotriazolyl c-kit inhibitors
    Publication number: 20070232669
    Abstract: Compounds represented by Formula (I): or a pharmaceutically acceptable salt or N-oxide thereof, are useful in the treatment of cancer.
    Type: Application
    Filed: February 6, 2007
    Publication date: October 4, 2007
    Inventors: Andrew Crew, Lee Arnold, Radoslaw Laufer
  • Bicyclic protein kinase inhibitors
    Publication number: 20070149521
    Abstract: Compounds of the Formula and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit protein kinase enzymes and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions of the central nervous system.
    Type: Application
    Filed: December 4, 2006
    Publication date: June 28, 2007
    Inventors: Andrew Crew, Han-Qing Dong, Mark Mulvihill, Douglas Werner, Mridula Kadalbajoo, Radoslaw Laufer
  • 6,6-Bicyclic ring substituted heterobicyclic protein kinase inhibitors
    Publication number: 20060235031
    Abstract: Compounds of the formula and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions of the central nervous system.
    Type: Application
    Filed: March 31, 2005
    Publication date: October 19, 2006
    Inventors: Lee Arnold, Heather Coate, Andrew Crew, Hanqing Dong, Kenneth Foreman, Ayako Honda, Radoslaw Laufer, An-Hu Li, Kristen Mulvihill, Mark Mulvihill, Anthony Nigro, Bijoy Panicker, Arno Steinig, Qingua Weng, Douglas Werner, Michael Wyle, Tao Zhang, Cara Cesario, Yingchuan Sun
  • N-substituted benzimidazolyl c-Kit inhibitors
    Publication number: 20060189629
    Abstract: Compounds represented by Formula (I): or a pharmaceutically acceptable salt or N-oxide thereof, are useful in the treatment of cancer.
    Type: Application
    Filed: August 16, 2004
    Publication date: August 24, 2006
    Inventors: Joshua Bolger, Arlindo Castelhano, Andrew Crew, Han-Qing Dong, Ayako Honda, Radoslaw Laufer, An-Hu Li, Kristen Mulvihill, Li Qiu, Colin Sambrook Smith, Yingchaun Sun, Graham Wynne, Tao Zhang
  • N-substituted benzimidazolyl c-Kit inhibitors and combinatorial benzimidazole library
    Publication number: 20060116402
    Abstract: Compounds represented by Formula (I): or a pharmaceutically acceptable salt or N-oxide thereof, are useful in the treatment of tumors. Combinatorial libraries composed of compounds represented by Formula (I) or benzimidazole compounds represented by Formula (II): are useful in providing compounds to assay for such therapeutically useful compounds.
    Type: Application
    Filed: November 30, 2005
    Publication date: June 1, 2006
    Inventors: Andrew Crew, Matthew Cox, Radoslaw Laufer, Neil Pegg, Colin Sambrook Smith, Yingchuan Sun, Robin Wilkes, Jonathan Williams
  • N-substituted pyrazolyl-amidyl-benzimidazolyl c-Kit inhibitors
    Publication number: 20060035951
    Abstract: Compounds represented by Formula (I): or a pharmaceutically acceptable salt or N-oxide thereof, are useful in the treatment of cancer.
    Type: Application
    Filed: August 16, 2004
    Publication date: February 16, 2006
    Inventors: Joshua Bolger, Arlindo Castelhano, Andrew Crew, Radoslaw Laufer, An-Hu Li, Colin Sambrook Smith, Yingchuan Sun
  • N3-substituted imidazopyridine c-Kit inhibitors
    Publication number: 20060035921
    Abstract: Compounds represented by Formula (I): or a pharmaceutically acceptable salt or N-oxide thereof, are useful in the treatment of cancer.
    Type: Application
    Filed: August 16, 2004
    Publication date: February 16, 2006
    Inventors: Arlindo Castelhano, Andrew Crew, Han-Qing Dong, Radoslaw Laufer, An-Hu Li, Li Qiu, Colin Sambrook Smith, Tao Zhang