Patents by Inventor Radu A. Moise

Radu A. Moise has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating obesity or an obesity related condition
    Patent number: 8889660
    Abstract: In one aspect of the present invention, a pharmaceutical composition for treating a metabolic disease in a mammalian subject includes a therapeutically effective amount of (R)-all-trans-13,14-dihydroretinol and a pharmaceutically acceptable carrier or diluent. In another aspect of the present invention, pharmaceutical composition for treating a metabolic disease in a mammalian subject includes a therapeutically effective amount of (S)-all-trans-13,14-dihydroretinol and a pharmaceutically acceptable carrier or diluent. In a further aspect of the present invention, a method is provided for treating a metabolic disease in a mammalian subject. The method includes administering to the subject a pharmaceutical composition comprising at least one all-trans-13,14-dihydroretinoid, all-trans-13,14-dihydroretinoid derivative, or agent capable of modulating the level of at least one all-trans-13,14-dihydroretinoid or all-trans-13,14-dihydroretinoid derivative in the subject.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: November 18, 2014
    Assignee: Case Western Reserve University
    Inventors: Krzysztof Palczewski, Radu Moise
  • Methods for treating metabolic diseases
    Patent number: 8338394
    Abstract: A pharmaceutical composition for treating a metabolic disease in a mammalian subject includes a therapeutically effective amount of all-trans-13,14-dihydroretinoid, all-trans-13,14-dihydroretinoid derivative, or agent capable of modulating the level of at least one all-trans-13,14-dihydroretinoid or all-trans-13,14-dihydroretinoid derivative in the subject.
    Type: Grant
    Filed: October 9, 2007
    Date of Patent: December 25, 2012
    Assignee: Case Western Reserve University
    Inventors: Krzysztof Palczewski, Radu A. Moise
  • COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISEASES
    Publication number: 20100135977
    Abstract: A pharmaceutical composition for treating a metabolic disease in a mammalian subject includes a therapeutically effective amount of all-trans-13,14-dihydroretinoid, all-trans-13,14-dihydroretinoid derivative, or agent capable of modulating the level of at least one all-trans-13,14-dihydroretinoid or all-trans-13,14-dihydroretinoid derivative in the subject.
    Type: Application
    Filed: October 9, 2007
    Publication date: June 3, 2010
    Inventors: Krzysztof Palczewski, Radu A. Moise