Patents by Inventor Radu Lazar

Radu Lazar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymer synthesis using electrowetting devices
    Patent number: 12129501
    Abstract: The invention relates to methods of synthesizing polymers, biopolymers, and nucleic acids, to immobilised dNTP/NTPs and kits comprising said immobilised dNTP/NTPs for use in said methods of nucleic acid synthesis.
    Type: Grant
    Filed: September 6, 2022
    Date of Patent: October 29, 2024
    Assignee: Nuclera Ltd.
    Inventors: Michael Chen, Jiahao Huang, Radu Lazar, Gordon McInroy
  • Compositions and Methods Related to Nucleic Acid Synthesis
    Publication number: 20240084350
    Abstract: The invention relates to the use of specific terminal deoxynucleotidyl transferase (TdT) enzymes in a method of nucleic acid synthesis, to methods of synthesizing nucleic acids, and to the use of kits comprising said enzymes in a method of nucleic acid synthesis. The invention also relates to the use of terminal deoxynucleotidyl transferases and 3?-blocked nucleotide triphosphates in a method of template independent nucleic acid synthesis.
    Type: Application
    Filed: September 21, 2023
    Publication date: March 14, 2024
    Applicant: Nuclera Ltd.
    Inventors: Michael C. Chen, Radu A. Lazar, Jiahao Hung, Gordon R. Mclnroy
  • Compositions and methods related to nucleic acid synthesis
    Patent number: 11807887
    Abstract: The invention relates to the use of specific terminal deoxynucleotidyl transferase (TdT) enzymes in a method of nucleic acid synthesis, to methods of synthesizing nucleic acids, and to the use of kits comprising said enzymes in a method of nucleic acid synthesis. The invention also relates to the use of terminal deoxynucleotidyl transferases and 3?-blocked nucleotide triphosphates in a method of template independent nucleic acid synthesis.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: November 7, 2023
    Assignee: Nuclera, Ltd.
    Inventors: Michael C. Chen, Radu A. Lazar, Jiahao Huang, Gordon R. McInroy
  • POLYMER SYNTHESIS USING ELECTROWETTING DEVICES
    Publication number: 20230087259
    Abstract: The invention relates to methods of synthesizing polymers, biopolymers, and nucleic acids, to immobilised dNTP/NTPs and kits comprising said immobilised dNTP/NTPs for use in said methods of nucleic acid synthesis.
    Type: Application
    Filed: September 6, 2022
    Publication date: March 23, 2023
    Applicant: Nuclera Nucleics Ltd.
    Inventors: Michael CHEN, Jiahao HUANG, Radu LAZAR, Gordon MCINROY
  • Nucleotide triphosphate immobilised on a support and their use in nucleic acid synthesis
    Patent number: 11466301
    Abstract: The invention relates to methods of synthesizing polymers, biopolymers, and nucleic acids, to immobilised dNTP/NTPs and kits comprising said immobilised dNTP/NTPs for use in said methods of nucleic acid synthesis.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: October 11, 2022
    Assignee: Nuclera Nucleics Ltd.
    Inventors: Michael Chen, Jiahao Huang, Radu Lazar, Gordon McInroy
  • Compositions and Methods Related to Nucleic Acid Synthesis
    Publication number: 20220112534
    Abstract: The invention relates to the use of specific terminal deoxynucleotidyl transferase (TdT) enzymes in a method of nucleic acid synthesis, to methods of synthesizing nucleic acids, and to the use of kits comprising said enzymes in a method of nucleic acid synthesis. The invention also relates to the use of terminal deoxynucleotidyl transferases and 3?-blocked nucleotide triphosphates in a method of template independent nucleic acid synthesis.
    Type: Application
    Filed: December 17, 2021
    Publication date: April 14, 2022
    Applicant: Nuclera Nucleics Ltd.
    Inventors: Michael C. Chen, Radu A. Lazar, Jiahao Huang, Gordon R. McInroy
  • Compositions and methods related to nucleic acid synthesis
    Patent number: 11236377
    Abstract: The invention relates to the use of specific terminal deoxynucleotidyl transferase (TdT) enzymes in a method of nucleic acid synthesis, to methods of synthesizing nucleic acids, and to the use of kits comprising said enzymes in a method of nucleic acid synthesis. The invention also relates to the use of terminal deoxynucleotidyl transferases and 3?-blocked nucleotide triphosphates in a method of template independent nucleic acid synthesis.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: February 1, 2022
    Assignee: Nuclera Nucleics Ltd.
    Inventors: Michael C. Chen, Radu A. Lazar, Jiahao Huang, Gordon R. McInroy
  • COMPOSITIONS AND METHODS RELATED TO NUCLEIC ACID PREPARATION
    Publication number: 20210261998
    Abstract: The invention relates to a method of nucleic acid synthesis comprising the use of 3?-O-azidomethyl blocked nucleotide triphosphates which comprises the step of adding a capping group to any uncleaved 3?-O-azidomethyl groups and to the use of kits comprising said capping groups in a method of nucleic acid synthesis. The invention also relates to capped nucleotide triphosphates and 3?-O-azidomethyl capping groups.
    Type: Application
    Filed: February 16, 2021
    Publication date: August 26, 2021
    Applicant: Nuclera Nucleics Ltd.
    Inventors: Michael C. Chen, Radu A. Lazar, Jiahao Huang, Gordon R. McInroy
  • Compositions and Methods Related to Nucleic Acid Synthesis
    Publication number: 20200332333
    Abstract: The invention relates to the use of specific terminal deoxynucleotidyl transferase (TdT) enzymes in a method of nucleic acid synthesis, to methods of synthesizing nucleic acids, and to the use of kits comprising said enzymes in a method of nucleic acid synthesis. The invention also relates to the use of terminal deoxynucleotidyl transferases and 3?-blocked nucleotide triphosphates in a method of template independent nucleic acid synthesis.
    Type: Application
    Filed: July 8, 2020
    Publication date: October 22, 2020
    Applicant: Nuclera Nucleics Ltd.
    Inventors: Michael C. Chen, Radu A. Lazar, Jiahao Huang, Gordon R. McInroy
  • Compositions and methods related to nucleic acid synthesis
    Patent number: 10745727
    Abstract: The invention relates to the use of specific terminal deoxynucleotidyl transferase (TdT) enzymes in a method of nucleic acid synthesis, to methods of synthesizing nucleic acids, and to the use of kits comprising said enzymes in a method of nucleic acid synthesis. The invention also relates to the use of terminal deoxynucleotidyl transferases and 3?-blocked nucleotide triphosphates in a method of template independent nucleic acid synthesis.
    Type: Grant
    Filed: February 10, 2016
    Date of Patent: August 18, 2020
    Assignee: Nuclera Nucleics Ltd.
    Inventors: Michael C. Chen, Radu A. Lazar, Jiahao Huang, Gordon R. McInroy
  • Nucleotide Triphosphate Immobilised on a Support and Their Use in Nucleic Acid Synthesis
    Publication number: 20190338331
    Abstract: The invention relates to methods of synthesizing polymers, biopolymers, and nucleic acids, to immobilised dNTP/NTPs and kits comprising said immobilised dNTP/NTPs for use in said methods of nucleic acid synthesis.
    Type: Application
    Filed: January 26, 2018
    Publication date: November 7, 2019
    Applicant: Nuclera Nucleics Ltd.
    Inventors: Michael Chen, Jiahao Huang, Radu Lazar, Gordon McInroy
  • Azidomethyl Ether Deprotection Method
    Publication number: 20180201968
    Abstract: The invention relates to a method of converting an azidomethyl ether substituent to a free hydroxyl group. The invention also relates to methods of nucleic acid synthesis and sequencing comprising the use of nucleotide triphosphates having a 3?-O-azidomethyl substituent, to kits comprising nucleotide triphosphates having a 3?-O-azidomethyl substituent and photoactivatable transition metal complex and to the use of said kits in methods of nucleic acid synthesis and sequencing.
    Type: Application
    Filed: July 15, 2016
    Publication date: July 19, 2018
    Inventors: Michael C. Chen, Radu A. Lazar, Jiahao Huang, Gordon R. McInroy
  • NOVEL USE
    Publication number: 20180023108
    Abstract: The invention relates to the use of specific terminal deoxynucleotidyl transferase (TdT) enzymes in a method of nucleic acid synthesis, to methods of synthesizing nucleic acids, and to the use of kits comprising said enzymes in a method of nucleic acid synthesis. The invention also relates to the use of terminal deoxynucleotidyl transferases and 3?-blocked nucleotide triphosphates in a method of template independent nucleic acid synthesis.
    Type: Application
    Filed: February 10, 2016
    Publication date: January 25, 2018
    Inventors: Michael C. CHEN, Radu A. LAZAR, Jiahao HUANG, Gordon R. MCINROY
  • A Process for the Preparation of Nucleic Acid by Means of 3'-O-Azidomethyl Nucleotide Triphosphate
    Publication number: 20180016609
    Abstract: The invention relates to a method of nucleic acid synthesis comprising the use of 3?-O-azidomethyl blocked nucleotide triphosphates which comprises the step of adding a capping group to any uncleaved 3?-O-azidomethyl groups and to the use of kits comprising said capping groups in a method of nucleic acid synthesis. The invention also relates to capped nucleotide triphosphates and 3?-O-azidomethyl capping groups.
    Type: Application
    Filed: March 3, 2016
    Publication date: January 18, 2018
    Inventors: Michael C. Chen, Radu A. Lazar, Jiahao Huang, Gordon R. McInroy
  • Integrated electronic compilation of study material
    Publication number: 20130042173
    Abstract: An apparatus and method to electronically compile an integrated summary document across several different educational sources is provided. The integrated summary document can contain links back to the original sources. Within the integrated summary document, searches, social learning elements and other content can also be integrated and linked to external content.
    Type: Application
    Filed: August 9, 2011
    Publication date: February 14, 2013
    Applicant: KNO, INC.
    Inventors: Babur Habib, David Straus, Osman Rashid, Adrian Muresan, Radu Lazar, Lehel Kulscar, Jakab Szaboles