Patents by Inventor Rafael A. Nieves

Rafael A. Nieves has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cellobiohydrolase I gene and improved variants
    Publication number: 20030170861
    Abstract: A nucleic acid molecule having a nucleic acid sequence that encodes a linker region of exoglucanase, said nucleic acid sequence comprising the nucleic sequence 5′-GGCGGAAACCCGCCTGGCACCACC-3′.
    Type: Application
    Filed: January 14, 2002
    Publication date: September 11, 2003
    Inventors: William S. Adney, Stephen R. Decker, Suzanne McCarter, John O. Baker, Rafael Nieves, Michael E. Himmel, Todd B. Vinzant
  • Low molecular weight thermostable .beta.-D-glucosidase from acidothermus cellulolyticus
    Patent number: 5432075
    Abstract: A purified low molecular weight .beta.-D-glucosidase is produced from Acidothermus cellulolyticus ATCC 43068. The enzyme is water soluble, possesses activity against pNP-.beta.-D-glucopyranoside, has a high of degree of stability toward heat, exhibits optimal temperature activity at about 65.degree. C. at a pH range of from about 2 to about 7, has an inactivation temperature of about 80.degree. C. at a pH range of from about 2 to about 7 and has a molecular weight of about 50.5-54.5 kD as determineded by SDS-PAGE.
    Type: Grant
    Filed: July 15, 1994
    Date of Patent: July 11, 1995
    Assignee: Midwest Research Institute
    Inventors: Michael E. Himmel, Melvin P. Tucker, William S. Adney, Rafael A. Nieves
  • Thermostable purified endoglucanase II from Acidothermus cellulolyticus ATCC
    Patent number: 5366884
    Abstract: A purified low molecular weight endoglucanase II from Acidothermus cellulolyticus (ATCC 43068) is disclosed. The endoglucanase is water soluble, possesses both C.sub.1, and C.sub.x types of enzyme activity, a high degree of stability toward heat, and exhibits optimum temperature activity at about 81.degree. C. at pH's from about 2 to about 9, and at a inactivation temperature of about 100.degree. C. at pH's from about 2 to about 9.
    Type: Grant
    Filed: September 21, 1993
    Date of Patent: November 22, 1994
    Assignee: Midwest Research Institute
    Inventors: William S. Adney, Steven R. Thomas, Rafael A. Nieves, Michael E. Himmel