Patents by Inventor Rafael Crabbé

Rafael Crabbé has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of Hepatitis C Virus Infection with Alisporivir
    Publication number: 20160235808
    Abstract: The invention concerns the use of cyclophilin inhibitors in the treatment of Hepatitis C virus infection.
    Type: Application
    Filed: April 28, 2016
    Publication date: August 18, 2016
    Inventors: Claudio Avila, Rafael Crabbe
  • New Treatments of Hepatitis C Virus Infection
    Publication number: 20150258167
    Abstract: The invention concerns the use of cyclophilin inhibitors in the treatment of Hepatitis C virus genotype 2 or 3 infection.
    Type: Application
    Filed: May 28, 2015
    Publication date: September 17, 2015
    Inventors: Claudio Avila, Rafael Crabbé, Nikolai Naoumov
  • Treatments of Hepatitis C virus infection
    Publication number: 20150104415
    Abstract: The invention concerns the use of cyclophilin inhibitors in the treatment of Hepatitis C virus infection.
    Type: Application
    Filed: April 11, 2012
    Publication date: April 16, 2015
    Applicants: DEBIOPHARM INTERNATIONAL SA, NOVARTIS AG
    Inventors: Claudio Avila, Rafael Crabbe
  • New Treatments of Hepatitis C Virus Infection
    Publication number: 20130225483
    Abstract: The invention concerns the use of cyclophilin inhibitors in the treatment of Hepatitis C virus genotype 2 or 3 infection.
    Type: Application
    Filed: October 3, 2011
    Publication date: August 29, 2013
    Inventors: Claudio Avila, Rafael Crabbé, Nikolai Naoumov
  • Cycloundecadepsipeptide compounds and use of said compounds as a medicament
    Patent number: 8501683
    Abstract: At least one embodiment of the present invention relates to new cycloundecadepsipeptide compounds and to the use of said compounds as a medicament, in particular as antiviral agents, more particularly for preventing or treating Hepatitis C infections or HCV induced disorders.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: August 6, 2013
    Assignee: Debio Recherche Pharmaceutique S.A.
    Inventors: Roland Wenger, Manfred Mutter, Patrick Garrouste, Robert Lysek, Olivier Turpin, Grégoire Vuagniaux, Valérie Nicolas, Laura Novaroli Zanolari, Rafael Crabbé
  • Non-immunosuppressive cyclosporin for treatment of Ullrich congenital muscular dystrophy
    Patent number: 8450281
    Abstract: The present invention relates to the use of a nonimmunosuppressive cyclosporin A derivative for reducing mitochondrial dysfunction and the rate of apoptosis of muscle cells of patients diagnosed with Ullrich congenital muscular dystrophy or Bethlem myopathy.
    Type: Grant
    Filed: January 3, 2008
    Date of Patent: May 28, 2013
    Assignee: Debiopharm S.A.
    Inventors: Paolo Bernardi, Gregoire Vuagniaux, Rafael Crabbe
  • CYCLOUNDECADEPSIPEPTIDE COMPOUNDS AND USE OF SAID COMPOUNDS AS A MEDICAMENT
    Publication number: 20110212057
    Abstract: At least one embodiment of the present invention relates to new cycloundecadepsipeptide compounds and to the use of said compounds as a medicament, in particular as antiviral agents, more particularly for preventing or treating Hepatitis C infections or HCV induced disorders.
    Type: Application
    Filed: November 6, 2009
    Publication date: September 1, 2011
    Applicant: Debio Recherche Pharmaceutique S.A.
    Inventors: Roland Wenger, Manfred Mutter, Patrick Garrouste, Robert Lysex, Olivier Turpin, Grégoire Vuagniaux, Valérie Nicolas, Laura Novaroli Zanolari, Rafael Crabbé
  • NON-IMMUNOSUPPRESSIVE CYCLOSPORIN FOR TREATMENT OF ULLRICH CONGENITAL MUSCULAR DYSTROPHY
    Publication number: 20100041593
    Abstract: The present invention relates to the use of a nonimmunosuppressive cyclosporin A derivative for reducing mitochondrial dysfunction and the rate of apoptosis of muscle cells of patients diagnosed with Ullrich congenital muscular dystrophy or Bethlem myopathy.
    Type: Application
    Filed: January 3, 2008
    Publication date: February 18, 2010
    Inventors: Paolo Bernardi, Gregoire Vuagniaux, Rafael Crabbe