Patents by Inventor Rafael Ezra

Rafael Ezra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230345992
    Abstract: The invention provides compositions that increase oral bioavailability of edible lipophilic substances such as beneficial edible oils, oil-soluble vitamins, and nutraceuticals. The compositions and methods of the invention are highly applicable to food industries in the production of foods, beverages, supplements, and food additives.
    Type: Application
    Filed: July 29, 2021
    Publication date: November 2, 2023
    Inventor: Rafael Ezra
  • Publication number: 20230321031
    Abstract: The invention discloses particular water-dispersible solid formulation of a cannabinoid or a cannabis extract, wherein they are present in the form of a nanoemulsion, and upon dispersion in water said formulation produces nanoparticles (droplets of a submicron size) with an average size of up to about 500 nm. The present disclosure further relates to methods of making thereof, as well as therapeutic applications in humans for treating disorders and broader application for a range of medical conditions.
    Type: Application
    Filed: June 14, 2023
    Publication date: October 12, 2023
    Inventors: Shlomo Magdassi, Liraz Larush, Rafael Ezra
  • Publication number: 20230270678
    Abstract: A solid water-dispersible composition of matter comprising at least one sugar, at least one polysaccharide and at least one surfactant and at least one lipophilic active pharmaceutical ingredient (API), the composition comprises a plurality of micrometric particles each comprising a plurality of lipophilic nanospheres with an average size in the range of 50-900 nm, the at least one lipophilic API is contained in the micrometric particles and is distributed inside and/or outside the lipophilic nanospheres at predetermined proportions, thereby providing an improved delivery of the at least one lipophilic API. A sugar particle comprising a porous sugar material and lipophilic nanospheres having average sizes between 50-900 nm so that the lipophilic nanospheres are comprised within the porous sugar material, the sugar particle comprises at least one edible sugar, at least one edible oil, at least one edible polysaccharide, at least one edible surfactant and at least one lipophilic API.
    Type: Application
    Filed: July 29, 2021
    Publication date: August 31, 2023
    Inventor: Rafael Ezra
  • Patent number: 11712430
    Abstract: The invention discloses particular water-dispersible solid formulation of a cannabinoid or a cannabis extract, wherein they are present in the form of a nanoemulsion, and upon dispersion in water said formulation produces nanoparticles (droplets of a submicron size) with an average size of up to about 500 nm. The present disclosure further relates to methods of making thereof, as well as therapeutic applications in humans for treating disorders and broader application for a range of medical conditions.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: August 1, 2023
    Assignee: Karnak Technologies, LLC
    Inventors: Shlomo Magdassi, Liraz Larush, Rafael Ezra
  • Publication number: 20230147292
    Abstract: The invention generally provides a range of compositions and methods that are highly applicable to the field of cosmetics. The invention applies a nanotechnological approach to produce a new generation of compositions providing an improved topical and dermal delivery of lipophilic actives, and specifically non-therapeutic actives that serve as a basis for a range of skin care, personal care, and fragrance products.
    Type: Application
    Filed: July 29, 2021
    Publication date: May 11, 2023
    Inventor: Rafael Ezra
  • Publication number: 20220023209
    Abstract: Pharmaceutical compositions designed to deliver Vitamin D efficiently to the eyes and methods for using same are described herein. More particularly, ophthalmic pharmaceutical compositions for use in protecting eyes from the harmful effects of light exposure, in maintaining a healthy ocular state, and in treating disorders of the eye are described herein. The composition may also be used as a medical device which, once on the surface of the eye, creates a layer that filters electro-magnetic radiation in different wave lengths. The composition may also be used as a medical device which eases the symptoms and signs of eye-surface conditions.
    Type: Application
    Filed: December 6, 2019
    Publication date: January 27, 2022
    Inventors: Rafael Ezra, Yoni Manor
  • Publication number: 20210059975
    Abstract: The invention discloses particular water-dispersible solid formulation of a cannabinoid or a cannabis extract, wherein they are present in the form of a nanoemulsion, and upon dispersion in water said formulation produces nanoparticles (droplets of a submicron size) with an average size of up to about 500 nm. The present disclosure further relates to methods of making thereof, as well as therapeutic applications in humans for treating disorders and broader application for a range of medical conditions.
    Type: Application
    Filed: March 11, 2019
    Publication date: March 4, 2021
    Inventors: Shlomo Magdassi, Liraz Larush, Rafael Ezra