Patents by Inventor Rafael Ferritto

Rafael Ferritto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective peroxisome proliferator activated receptor modulators
    Patent number: 7321056
    Abstract: The present invention is directed to a novel compound, its composition and use of a compound having a structural formula (I), or a pharmaceutically acceptable salt, solvate, hydrate or stereoisomers thereof, which is useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR) such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases
    Type: Grant
    Filed: December 8, 2004
    Date of Patent: January 22, 2008
    Assignee: Eli Lilly and Company
    Inventors: Rafael Ferritto Crespo, Maria Dolores Martin-Ortega Finger
  • Amide linker peroxisome proliferator activated receptor modulators
    Patent number: 7220880
    Abstract: The present invention is directed to compounds, compositions, and use of compounds the structural Formula (I)
    Type: Grant
    Filed: June 11, 2003
    Date of Patent: May 22, 2007
    Assignee: Eli Lilly and Company
    Inventors: Rafael Ferritto Crespo, Jose Alfredo Martin, Maria Dolores Martin-Ortega Finger, Isabel Rojo Garcia, Quanrong Shen, Alan M Warshawsky, Yanping Xu
  • Selective peroxisome proliferator activated receptor modulators
    Publication number: 20070066683
    Abstract: The present invention is directed to a novel compound, its composition and use of a compound having a structural formula (I), or a pharmaceutically acceptable salt, solvate, hydrate or stereoisomers thereof, which is useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR) such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases.
    Type: Application
    Filed: December 8, 2004
    Publication date: March 22, 2007
    Inventors: Rafael Ferritto Crespo, Maria Martin-Ortega Finger
  • Modulators of peroxisome proliferator activated receptors
    Patent number: 7192982
    Abstract: Disclosed is a compound represented by Structural Formula (I): Ar is a substituted or unsubstituted aromatic group. Q is a covalent bond, —CH2— or —CH2CH2—; W is a substituted or unsubstituted alkylene or a substituted or unsubstituted heteroalkylene linking group from two to ten atoms in length, preferably from two to seven atoms in length.
    Type: Grant
    Filed: May 30, 2002
    Date of Patent: March 20, 2007
    Assignees: Ligand Pharmaceuticals, Inc., Eli Lilly and Company
    Inventors: Dawn Alisa Brooks, Alan M. Warshawsky, Chahrzad Montrose-Rafezadeh, Anne-Reifel Miller, Lourdes Prieto, Isabel Rojo, Jose Alfredo Martin, Maria Rosario Gonzales Garcia, Alicia Torrado, Rafael Ferritto Crespo, Carlos Lamas-Peteira, Robert J. Ardecky, Maria Martin-Ortega Finger
  • Amide linker peroxisome proliferator activated receptor modulators
    Publication number: 20060111406
    Abstract: The present invention is directed to compounds, compositions, and use of compounds the structural Formula (I).
    Type: Application
    Filed: June 11, 2003
    Publication date: May 25, 2006
    Applicant: Eli Lilly and Company
    Inventors: Rafael Ferritto Crespo, Jose Martin, Maria Martinortega Finger, Isabel Rojo Garcia, Quanrong Shen, Alan Warshawsky, Yanping Xu
  • Prodrugs of excitatory amino acids
    Publication number: 20050009912
    Abstract: This invention relates to synthetic excitatory amino acid prodrugs of formula (I) wherein the residue R11, R12 and R13 are aas defined in claim 1. The invention further relates to processes for the preparation of the compounds of formula (I), and to pharmaceutical compositions for the treatment of neurological and psychiatric disorders comprising said compounds.
    Type: Application
    Filed: December 5, 2002
    Publication date: January 13, 2005
    Inventors: Ana Bueno Melendo, Alfonso De Dios, Carmen Dominguez-Fernandez, Rafael Ferritto Crespo, Jose Martin, Maria Martinez-Grau, Steven Massey, James Monn, Concepcion Pedregal-Tercero, Matthew Valli, Marc Herin
  • Prodrugs of excitatory amino acids
    Publication number: 20040176459
    Abstract: This invention relates to synthetic excitatory amino acid prodrugs and processes for their preparation. The invention further relates to methods of using, and pharmaceutical compositions comprising, the compounds for the treatment of neurological disorders and psychiatric disorders.
    Type: Application
    Filed: December 10, 2003
    Publication date: September 9, 2004
    Inventors: Ana Belen Bueno Melendo, Alfonso De Dios, Carmen Dominguez-Fernandez, Luisa Maria Martin-Cabrejas, Jose Alfredo Martin, Carlos Montero Salgado, Concepcion Pedregal-Tercero, Rafael Ferritto Crespo, Marc Francis Herin, Maria Angeles Martinez-Grau, Steven Marc Massey, James Allen Monn, Matthew John Valli
  • Fluorous reaction and separation systems
    Patent number: 6156896
    Abstract: The present invention provides several methods of synthesis and separation in which organic/fluorous phase separation techniques are used to effect separations. The present invention also provides novel compositions of matter comprising fluorous Si, Sn and Ge compounds.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: December 5, 2000
    Assignee: University of Pittsburgh
    Inventors: Dennis P. Curran, Sabine Hadida Ruah, Masahide Hoshino, Armido Studer, Peter Wipf, Patrick Jeger, Sun-Young Kim, Rafael Ferritto
  • Fluorous reaction and separation systems
    Patent number: 5859247
    Abstract: The present invention provides several methods of synthesis and separation in which organic/fluorous phase separation techniques are used to effect separations. The present invention also provides novel compositions of matter comprising fluorous Si, Sn and Ge compounds.
    Type: Grant
    Filed: July 31, 1996
    Date of Patent: January 12, 1999
    Assignee: University of Pittsburgh
    Inventors: Dennis P. Curran, Sabine Hadida Ruah, Masahide Hoshino, Armido Studer, Peter Wipf, Patrick Jeger, Sun-Young Kim, Rafael Ferritto