Abstract: In vitro pharmacogenomic screening method for anticipating a patient's response to the treatment of ocular hypertension A method for in vitro screening a patient's response to the treatment of ocular hypertension involves obtaining a sample of a biological fluid from a patient, and determining the number of copies of an intronic portion of gene MLIP (MLIP-AS1). Detection of more than one copy of said MLIP-AS1 is an indication that the patient is a responder to a treatment with prostaglandins. Detection of less than one copy of MLIP-AS1 is an indication that the patient is a responder to a treatment with ?-blockers.

Abstract: Implanting device for intrastromal prosthesis that introduces segment (ring) onto inside of intrastromal tunnel in a patient's cornea. Device includes a ring holder having clamp to support segment to be inserted and a cylinder base having hollow cylindrical shape and first and second cylinder ends. Rotatable impeller tip device, including an impeller tip arm and impeller tip, is joined to first cylinder end and over ring holder, a protective element arranged to protect clamp that is positionable over rotatable impeller tip device, and a block cover, arranged on second cylinder end. A rod, projecting from block cover and into cylinder base has a free end with a recess that separates a first wall configured to concurrently move clamp and impeller tip arm in a first direction and a second wall configured to move clamp relative to impeller tip arm in a second direction opposite first direction.

Abstract: The scleral epimacular implant comprises an arm (6) with a curved configuration, having a first end (1), which can be affixed to a retina (8). The arm (6) comprises a second end (3) comprising a discoidal element (4), whose internal face facing the curvature of the arm (6) is constituted as an indentation platform (5), configured to be in contact with the retina (8) when the implant is placed in said retina (8).