Patents by Inventor Rafael Jesus Apitz-Castro

Rafael Jesus Apitz-Castro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thermostable Inhibitors of Activation of the Blood Clotting System Through Contact with Foreign Surfaces
    Publication number: 20140296146
    Abstract: The present invention relates to the field of blood clotting. Specifically, the invention relates to particular inhibitors of artificial activation of the blood clotting process through contact with foreign surfaces.
    Type: Application
    Filed: August 20, 2012
    Publication date: October 2, 2014
    Applicants: Synapse B.V., Universiteit Maastricht
    Inventors: Tilman Mathias Hackeng, Dennis Peter Leonardo Suijlen, Hendrik Coenraad Hemker, Rafael Jesus Apitz-Castro
  • Method and assembly for measuring thrombin generation in plasma
    Patent number: 8828730
    Abstract: Disclosed is a method for measuring thrombin generation in a whole blood sample. The whole blood sample may be applied forthwith, without prior processing. The blood cells and blood plasma in the whole blood sample are separated by (lateral) flow migration. Also disclosed is an assembly of a sample support and a device dedicated to measure thrombin generation in a whole blood sample. Advantageously, the sample support comprises a separator medium allowing separation of whole blood into blood cells and blood plasma by means of (lateral) flow migration.
    Type: Grant
    Filed: August 5, 2009
    Date of Patent: September 9, 2014
    Assignee: Synapse B.V.
    Inventors: Hendrik Coenraad Hemker, Rafael Jesus Apitz-Castro, Sebastiaan Nijhuis
  • METHOD AND ASSEMBLY FOR MEASURING THROMBIN GENERATION IN PLASMA
    Publication number: 20110195441
    Abstract: Disclosed is a method for measuring thrombin generation in a whole blood sample. The whole blood sample may be applied forthwith, without prior processing. The blood cells and blood plasma in the whole blood sample are separated by (lateral) flow migration. Also disclosed is an assembly of a sample support and a device dedicated to measure thrombin generation in a whole blood sample. Advantageously, the sample support comprises a separator medium allowing separation of whole blood into blood cells and blood plasma by means of (lateral) flow migration.
    Type: Application
    Filed: August 5, 2009
    Publication date: August 11, 2011
    Inventors: Hendrik Coenraad Hemker, Rafael Jesus Apitz-Castro, Sebastiaan Nijhuis