Patents by Inventor Rafael Jorda

Rafael Jorda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5780579
    Abstract: The present invention relates to a method for the preparation of polyamino acids, with controlled molecular weights, by polymerization of N-carboxyanhydrides (NCAs) of at least one amino acid, using at least one initiator of the strong base type and in liquid medium, characterized in that it consists in including, in the liquid reaction medium, given amounts of water and/or of alcohol. Application: synthesis of polyamino acids with mechanical and rheological characteristics adapted to applications as biomaterials.
    Type: Grant
    Filed: March 28, 1996
    Date of Patent: July 14, 1998
    Assignee: Flamel Technologies (Societe Anonyme)
    Inventors: Gerard Soula, Jean-Michel Grosselin, Rafael Jorda, Catherine Castan
  • Patent number: 5585050
    Abstract: The invention relates to microcapsules containing at least one active ingredient, characterized in that they are constituted by:an hydrophilic and essentially non-aqueous liquid inner core, formed of a solution of at least one active ingredient which is water-soluble and amphiphilic in at least one non-aqueous hydrophilic solvent, andby a wall, enclosing said inner core and based on at least one polymer or copolymer, and to one of their preparation methods.The invention finds an application in systems of instant release of active ingredient, such as articles of hygiene, surgical gloves and materials.
    Type: Grant
    Filed: June 24, 1993
    Date of Patent: December 17, 1996
    Assignee: Flamel Technologies
    Inventors: Rafael Jorda, Pierre Autant, Rossin Rene
  • Patent number: 5441742
    Abstract: The present invention relates to a cellular cellulosic material containing a biocide agent and to a process for preparing same. Characteristically, matrix type microparticles, containing at least one biocide agent, are distributed in the network of cellulose of said material, ensuring therein, in the presence of moisture or water, a controlled release of the biocide agent or agents.
    Type: Grant
    Filed: March 21, 1994
    Date of Patent: August 15, 1995
    Assignee: Financiere Elysees Balzac
    Inventors: Pierre Autant, Christophe Chalvin, Claudine Colin, Rafael Jorda, Jean-Luc Wertz
  • Patent number: 5169641
    Abstract: Polyester/silicon co-crosslinked polymer substrates at least partially degradable by hydrolysis, well adopted as matrices for the controlled release of a wide variety of active agents therefrom, are prepared by controlledly co-crosslinking (a) at least one diorganopolysiloxane having at least two hydroxyl groups per molecule and (b) an oligomeric polylactic and/or polyglycolic polyester .alpha.,.omega.-diol, with an effective co-crosslinking amount of (c) an organic polyisocyanate.
    Type: Grant
    Filed: March 6, 1991
    Date of Patent: December 8, 1992
    Assignee: Rhone-Poulenc Chimie
    Inventors: Rafael Jorda, Hugues Porte, Ghislaine Torres
  • Patent number: 5064894
    Abstract: Non-agglomerating elastomeric organopolysiloxane particulates having a mean particle size ranging from 50 .mu.m to 3 mm, uniformly coated with silica powder on the face surfaces thereof and well adapted as a soft filler material for natural or synthetic polymers or as a controlled release dosage form, are produced by (a) forming an oil-in-water emulsion of .alpha.,.omega.-dihydroxydiorganopolysiloxane oils, silica powder, a platinum curing catalyst and, optionally, an active principle such as a medicament or an agrochemical, and then (b) breaking and polycondensation crosslinking such emulsion into the desired particles by heating it to a temperature ranging from 40.degree. to 100.degree. C.
    Type: Grant
    Filed: January 19, 1990
    Date of Patent: November 12, 1991
    Assignee: Rhone-Poulenc Chimie
    Inventors: Daniel Desmonceau, Rafael Jorda
  • Patent number: 5028653
    Abstract: Non-agglomerating elastomeric organopolysiloxane particulates having a mean particle size ranging from 50 .mu.m to 3 mm, uniformly coated with silica powder on the face surfaces thereof and well adapted as a soft filler material for natural or synthetic polymers or as a controlled release dosage form, are produced by (a) forming an oil-in-water emulsion of silicone oils, silica powder, a platinum curing catalyst and, optionally, an active principle such as a medicament or an agrochemical, and then (b) breaking and polyaddition crosslinking such emulsion into the desired particles by heating it to a temperature ranging from 40.degree. to 100.degree. C.
    Type: Grant
    Filed: January 19, 1990
    Date of Patent: July 2, 1991
    Assignee: Rhone-Poulenc Chimie
    Inventors: Daniel Desmonceau, Rafael Jorda