Patents by Inventor Rafael Ojeda

Rafael Ojeda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoparticles comprising antigens and adjuvants, and immunogenic structures
    Patent number: 9079765
    Abstract: Nanoparticles comprising adjuvants and antigens, such as tumor and pathogen antigens, are disclosed and their use in a range of applications such as for the treatment of cancer and infectious diseases. Immunogenic structures based on nanoparticles or antibodies with carbohydrate ligands, and their use for therapeutic and prophylactic purposes, and for the isolation and detection of antibodies directed against the carbohydrate structures.
    Type: Grant
    Filed: September 30, 2005
    Date of Patent: July 14, 2015
    Assignee: Midatech Ltd.
    Inventors: Gottfried Himmler, G. C. Mudde, Ralf Kircheis, Thomas William Rademacher, Soledad Penades Ullate, Manuel Martin Lomas, Jose Luis De Paz Carrera, Rafael Ojeda Martinez De Castilla, Africa Garcia Barrientes
  • Nanoparticles comprising antibacterial ligands
    Patent number: 9034380
    Abstract: Materials and Methods are disclosed for producing nanoparticles linked to antibacterial ligands, including antibiotics and/or molecules which bind to bacterial markers, and for the use of the nanoparticles for the treatment of conditions treatable by the antibiotic ligands.
    Type: Grant
    Filed: August 4, 2006
    Date of Patent: May 19, 2015
    Assignee: Midatech Ltd.
    Inventors: Thomas William Rademacher, Godfrey Bradman, Soledad Penades Ullate, Rafael Ojeda Martinez De Castilla
  • Process for the synthesis of unprotected pentasaccharides from a protected pentasaccharide precursor
    Patent number: 8822659
    Abstract: Procedure for the synthesis of deprotected pentasaccharides from a protected precursor pentasaccharide through a reaction procedure having five stages whereamong is included an N-sulphation of amino groups and a hydrogenolysis of benzyl groups. Through this procedure a drastic reduction is achieved in the total synthesis time in comparison with the process traditionally employed, together with increased reproducibility thereof, permitting the standardization thereof.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: September 2, 2014
    Assignee: Laboratorios Farmacéutios Rovi, S.A.
    Inventors: Ivan Lopez-Belmonte Encina, Rafael Ojeda Martinez De Castilla
  • PROCESS FOR THE SYNTHESIS OF UNPROTECTED PENTASACCHARIDES FROM A PROTECTED PENTASACCHARIDE PRECURSOR
    Publication number: 20110306757
    Abstract: Procedure for the synthesis of deprotected pentasaccharides from a protected precursor pentasaccharide through a reaction procedure having five stages whereamong is included an N-sulphation of amino groups and a hydrogenolysis of benzyl groups. Through this procedure a drastic reduction is achieved in the total synthesis time in comparison with the process traditionally employed, together with increased reproducibility thereof, permitting the standardisation thereof.
    Type: Application
    Filed: October 2, 2009
    Publication date: December 15, 2011
    Applicant: LABORATORIOS FARMACEUTICOS ROVI, S.A.
    Inventors: Ivan Lopez-Belmonte Encina, Rafael Ojeda Martinez De Castilla
  • NANOPARTICLES COMPRISING ANTIBACTERIAL LIGANDS
    Publication number: 20090181101
    Abstract: Materials and Methods are disclosed for producing nanoparticles linked to antibacterial ligands, including antibiotics and/or molecules which bind to bacterial markers, and for the use of the nanoparticles for the treatment of conditions treatable by the antibiotic ligands.
    Type: Application
    Filed: August 4, 2006
    Publication date: July 16, 2009
    Inventors: Thomas William Rademacher, Godfrey Bradman, Soledad Penades Ullate, Rafael Ojeda Martinez De Castilla
  • Nanoparticles Comprising Antigens and Adjuvants, and Immunogenic Structures
    Publication number: 20090104268
    Abstract: Nanoparticles comprising adjuvants and antigens, such as tumour and pathogen antigens, are disclosed and their use in a range of applications such as for the treatment of cancer and infectious diseases. Immunogenic structures based on nanoparticles or antibodies with carbohydrate ligands, and their use for therapeutic and prophylactic purposes, and for the isolation and detection of antibodies directed against the carbohydrate structures.
    Type: Application
    Filed: September 30, 2005
    Publication date: April 23, 2009
    Applicant: Midatech Limited
    Inventors: Gottfried Himmler, G. C. Mudde, Ralf Kircheis, Thomas William Rademacher, Soledad Penades Ullate, Manuel Martin Lomas, Jose Luis De Paz Carrera, Rafael Ojeda Martinez De Castilla, Africa Garcia Barrientes
  • Nanoparticles Comprising Rna Ligands
    Publication number: 20080213177
    Abstract: Materials and methods are provided for making nanoparticles having a core including metal and/or semiconductor atoms, which core is covalently linked to a plurality of ligands comprising a RNA ligand. The RNA ligands may include siRNA or miRNA. Also provided are uses of these nanoparticles in therapy and diagnosis.
    Type: Application
    Filed: May 24, 2005
    Publication date: September 4, 2008
    Inventors: Thomas William Rademacher, Manuel Martin-Lomas, Soledad Penades, Rafael Ojeda, African G. Barrientes, Khalid Gumaa