Patents by Inventor Rafael P. Alvarez-Ossorio

Rafael P. Alvarez-Ossorio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating leukemias using N-(2-dimethylaminoethyl)-3-amino-1,8-naphthalimide for treating leukemias and solid tumors
    Patent number: 5183821
    Abstract: N-(2-dimethylaminoethyl)-3-amino-1,8-naphthalimide (amonafide) is an effective agent for the treatment of leukemias and solid tumors.
    Type: Grant
    Filed: July 8, 1991
    Date of Patent: February 2, 1993
    Assignee: Laboratories Knoll, S.A.
    Inventors: Miguel F. Brana, Antonio M. Sanz, Rafael P. Alvarez-Ossorio, Cristobal M. Roldan, Cristina R. F. De Gamboa, Jesus G. Garcia, Jose M. C. Berlanga
  • N(Aminoalkyl)-naphthalimides and their derivatives
    Patent number: 4204063
    Abstract: N-substituted-3-substituted naphthalimides are prepared by reacting 3-substituted naphthalic acid with a compound having a primary amino group. The naphthalimides possess cytotoxic properties.
    Type: Grant
    Filed: June 2, 1978
    Date of Patent: May 20, 1980
    Assignee: Laboratorios Made, S.A.
    Inventors: Miguel F. Brana, Antonio M. Sanz, Rafael P. Alvarez-Ossorio, Cristobal M. Roldan, Cristina R. Fernandez de Gamboa