Patents by Inventor Rafael SELGAS

Rafael SELGAS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions containing steviosides
    Patent number: 10213452
    Abstract: The present invention relates to pharmaceutical compositions containing steviol glycoside and or steviol glycoside derivatives as well as to their use as osmotics in particular for use in the treatment of chronic renal failure by dialysis.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: February 26, 2019
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Abelardo Isaac Aguilera Peralta, Manuel Lopez-Cabrera, Rafael Selgas Gutierrez, Sonja Steppan, Jutta Passlick-Deetjen
  • METHOD AND KIT FOR DIAGNOSING EPITHELIAL-TO-MESENCHYMAL TRANSITION (EMT) OF THE PERITONEUM
    Publication number: 20180246098
    Abstract: The invention relates to the field of diagnosis of epithelial-to-mesenchymal transition (EMT), such as mesothelial-to-mesenchymal transition (MMT), in particular EMT of the peritoneum, which often occurs upon peritoneal dialysis. The invention provides a method and kit based on markers comprising at least one extracellular matrix protein, e.g., collagen 13, collagen 6, and/or keratin 34, at least one protein involved in building and/or restructuring of extracellular matrix, e.g., matrix metalloproteinase 1, at least one protein involved in cell-cell and/or cell-matrix contacts, e.g., cadherin 13 or thrombospondin 1, at least one growth factor, e.g., VEGF, and, optionally, at least one BMP antagonist, e.g., Gremlin 1.
    Type: Application
    Filed: September 8, 2016
    Publication date: August 30, 2018
    Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Jutta PLASSLICK-DEETJEN, Janine BUECHEL, Sonja STEPPAN, Manuel LOPEZ-CABRERA, Abelardo AGUILERA, Rafael SELGAS
  • PHARMACEUTICAL COMPOSITIONS CONTAINING STEVIOSIDES
    Publication number: 20170304335
    Abstract: The present invention relates to pharmaceutical compositions containing steviol glycoside and or steviol glycoside derivatives as well as to their use as osmotics in particular for use in the treatment of chronic renal failure by dialysis.
    Type: Application
    Filed: October 28, 2015
    Publication date: October 26, 2017
    Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Abelardo Isaac AGUILERA PERALTA, Manuel LOPEZ-CABRERA, Rafael SELGAS GUTIERREZ, Sonja STEPPAN, Jutta PASSLICK-DEEJEN