Patents by Inventor Rafael Shapiro

Rafael Shapiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030100803
    Abstract: The compositions 3-alkylated-5,5′,6,6′,7,7′,8,8′-octahydro-2,2′-binaphthol and 3,3′-dialkylated-5,5′,6,6′,7,7′,8,8′-octahydro-2,2′-binaphthol are disclosed, as well as various processes for making them, all involving the alkylation of 5,5′,6,6′,7,7′,8,8′-octahydro-2,2′-binaphthol.
    Type: Application
    Filed: November 26, 2001
    Publication date: May 29, 2003
    Inventors: Helen S.M. Lu, Weiming Qiu, Rafael Shapiro
  • Publication number: 20030100802
    Abstract: A process for making a compound of the formula 1
    Type: Application
    Filed: October 29, 2002
    Publication date: May 29, 2003
    Inventor: Rafael Shapiro
  • Patent number: 6555718
    Abstract: A process for making a compound of the formula I
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: April 29, 2003
    Assignee: E. I. du Pont de Nemours and Company
    Inventor: Rafael Shapiro
  • Patent number: 6489517
    Abstract: A process for making a compound of the formula I
    Type: Grant
    Filed: November 26, 2001
    Date of Patent: December 3, 2002
    Assignee: E. I. du Pont de Nemours and Company
    Inventor: Rafael Shapiro
  • Patent number: 6232489
    Abstract: A method for making arthropodicidal oxadiazines and intermediates which are racemic or enantiomerically enriched at their chiral center, the method for making the oxadiazines comprising reaction of an intermediate selected from as well as certain selected intermediates including those depicted above, and methods of making them.
    Type: Grant
    Filed: May 9, 2000
    Date of Patent: May 15, 2001
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Gary David Annis, Stephen Frederick McCann, Rafael Shapiro
  • Patent number: 6080856
    Abstract: A method for making arthropodicidal oxadiazines and intermediates which are racemic or enantiomerically enriched at their chiral center, the method for making the oxadiazines comprising reaction of an intermediate selected from ##STR1## wherein: R.sup.1 is F, Cl, or C.sub.1 -C.sub.3 fluoroalkoxy,R.sup.2 is C.sub.1 -C.sub.3 alkyl, andR.sup.4 is H or CO.sub.2 CH.sub.2 (C.sub.6 H.sub.5).as well as certain selected intermediates including those depicted above, and methods of making them.
    Type: Grant
    Filed: October 21, 1999
    Date of Patent: June 27, 2000
    Assignee: E. I. du Pont Nemours and Company
    Inventors: Gary David Annis, Stephen Frederick McCann, Rafael Shapiro
  • Patent number: 6063932
    Abstract: Arthropodicidal oxazoline derivatives and processes and intermediates for the preparation thereof are disclosed. The intermediates are racemic or enantiomerically enriched compounds having formula (I), wherein R and n are disclosed in the specification.
    Type: Grant
    Filed: May 13, 1999
    Date of Patent: May 16, 2000
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Gary David Annis, Rafael Shapiro
  • Patent number: 6018071
    Abstract: A method for making arthropodicidal oxadiazines and intermediates which are racemic or enantiomerically enriched at their chiral center, the method for making the oxadiazines comprising reaction of an intermediate selected from ##STR1## wherein: R.sup.1 is F, Cl, or C.sub.1 -C.sub.3 fluoroalkoxy,R.sup.2 is C.sub.1 -C.sub.3 alkyl, andR.sup.4 is H or CO.sub.2 CH.sub.2 (C.sub.6 H.sub.5).as well as certain selected intermediates including those depicted above, and methods of making them.
    Type: Grant
    Filed: October 2, 1998
    Date of Patent: January 25, 2000
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Gary David Annis, Stephen Frederick McCann, Rafael Shapiro
  • Patent number: 5869657
    Abstract: A method for making arthropodicidal oxadiazines and intermediates which are racemic or enantiomerically enriched at their chiral center, the method for making the oxadiazines comprising reaction of an intermediate selected from ##STR1## wherein: R.sup.1 is F, Cl, or C.sub.1 -C.sub.3 fluroalkoxy,R.sup.2 is C.sub.1 -C.sub.3 alkyl, andR.sup.4 is H or CO.sub.2 CH.sub.2 (C.sub.6 H.sub.5).as well as certain selected intermediates including those depicted above, and methods of making them.
    Type: Grant
    Filed: October 16, 1996
    Date of Patent: February 9, 1999
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Gary David Annis, Stephen Frederick McCann, Rafael Shapiro
  • Patent number: 5710306
    Abstract: A process to prepare a multidentate phosphite compound according to the general formula (1) ##STR1## in which n is 2-6, R is an n-valent organic group and R.sup.1 and R.sup.2 are fused aromatic ring systems with 2 or more rings, which rings are substituted on the ortho position relative to the oxygen atom only with hydrogen, by first preparing a phosphorochloridite compound from a R.sup.1 --OH and R.sup.2 --OH alcohol compound and a phosphorus chloride compound and subsequently contacting the phosphorochloridite compound with an alcoholic compound according to R--(OH).sub.n, wherein the phosphorochloridite is prepared by performing the two steps in a solvent:a) contacting a compound with the general formula: ##STR2## in which R.sup.3 and R.sup.4 are C.sub.1 -C.sub.4 alkyl groups, with the R.sup.1 OH and R.sup.2 OH compounds, andb) contacting the resulting compound of step (a) which has the formula (3): ##STR3## with HY, wherein Y is a halogen.
    Type: Grant
    Filed: March 15, 1996
    Date of Patent: January 20, 1998
    Assignees: DSM N.V., E. I. Du Pont de Nemours and Company
    Inventors: Carina S. Snijder, Antonius J. J. M. Teunissen, Carolina B. Hansen, Rafael Shapiro, James M. Garner
  • Patent number: 5705639
    Abstract: This invention includes compounds of Formula II and IV and a process for preparing Formula I compounds by first preparing the compounds of Formula IV and then further reacting to form the compounds of Formula II and further reacting to prepare the compounds of Formula I wherein Q, Z, R.sup.2 are as defined within.
    Type: Grant
    Filed: September 21, 1995
    Date of Patent: January 6, 1998
    Assignee: E. I. du Pont de Nemours and Company
    Inventor: Rafael Shapiro
  • Patent number: 5696280
    Abstract: Improved liquid phase process useful in the hydrocyanation of diolefinic compounds to produce nonconjugated acyclic nitriles and to the liquid phase process of isomerization of the nitriles to 3- and/or 4-monoalkene linear nitriles. The improvement involves conducting the process in the presence of zero-valent nickel and a multidentate phosphite ligand. The invention also provides a novel method of making phosphorochloridite.
    Type: Grant
    Filed: October 11, 1996
    Date of Patent: December 9, 1997
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Rafael Shapiro
  • Patent number: 5474998
    Abstract: Arthropodicidal pyrazoline, pyrazolidine and hydrazine compounds, including all their geometric and stereoisomers, agriculturally suitable salts thereof and compositions containing them; and a method for controlling arthropods employing said compounds which are: ##STR1## wherein Q, X, X.sup.1, Y and G are as defined in the text.
    Type: Grant
    Filed: February 16, 1993
    Date of Patent: December 12, 1995
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Charles R. Harrison, Renee M. Lett, Stephen F. McCann, Rafael Shapiro, Thomas M. Stevenson
  • Patent number: 4917719
    Abstract: Certain N-[(heterocyclic)aminocarbonyl]isothiazolesulfonamides, such as methyl 4-[[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]aminosulfonyl]-3-isoth iazolecarboxylate, are useful as herbicides and/or plant growth regulants.
    Type: Grant
    Filed: April 17, 1986
    Date of Patent: April 17, 1990
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Rafael Shapiro
  • Patent number: 4904299
    Abstract: Novel N-hydroxy-N'-sulfonylguanidine compounds are described which possess significant herbicidal and plant growth regulant activity for control of undesired vegetation.
    Type: Grant
    Filed: February 17, 1988
    Date of Patent: February 27, 1990
    Assignee: E. I. Du Pont de Nemours and Co.
    Inventor: Rafael Shapiro
  • Patent number: 4806142
    Abstract: Certain substituted pyrimidine sulfonylureas, such as 3-[[[-(4-dimethoxymethyl)-6-methylpyrimidin-2-yl]aminocarbonyl]aminosulfon yl]-2-thiophenecarboxylic acid, methyl ester, are selective pre-emergence and/or post-emergence herbicides.
    Type: Grant
    Filed: August 13, 1986
    Date of Patent: February 21, 1989
    Assignee: E. I. DuPont De Nemours and Company
    Inventor: Rafael Shapiro
  • Patent number: 4767445
    Abstract: This invention relates to novel ortho-(azinyl)benzenesulfonamides, such as N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]-2-(2-pyridinyl)benzene sulfonamide, and their use as pre-emergent or post-emergent herbicides or plant growth regulants.
    Type: Grant
    Filed: June 10, 1987
    Date of Patent: August 30, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Rafael Shapiro
  • Patent number: 4758262
    Abstract: This invention relates to herbicidally active propylene oxide derivatives, agriculturally suitable compositions thereof, and a method of using them as herbicides or plant growth regulants.
    Type: Grant
    Filed: December 13, 1985
    Date of Patent: July 19, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Rafael Shapiro
  • Patent number: 4750930
    Abstract: Novel N-hydroxy-N'-sulfonylguanidine compounds are described which possess significant herbicidal and plant growth regulant activity for control of undesired vegetation.
    Type: Grant
    Filed: June 10, 1987
    Date of Patent: June 14, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Rafael Shapiro
  • Patent number: 4723988
    Abstract: Thiophenesulfonamides such as N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-3-(isoxazol-3-yl)-2-thiophen esulfonamide are useful as herbicides and plant growth regulants.
    Type: Grant
    Filed: March 27, 1987
    Date of Patent: February 9, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Rafael Shapiro