Patents by Inventor Rafael Vazquez

Rafael Vazquez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240239696
    Abstract: Plant growth and energy storage is supported by complicated bio-electro-chemical processes causing the intake of water and nutrients from the ground. These processes are affected by adaptations such as root structure and genetic characteristics that facilitate a plant species' survival in its native regions. Disclosed are methods for altering the water and nutrient intake through electrical alignment of molecules with dipole characteristics and ionized molecules, and apparatus for performing the disclosed methods. Through the disclosed invention, the capacity of water molecules to interact at an electro-chemical level with soil elements can be increased or reduced to guide absorption-transport activity, facilitating optimal plant growth for agricultural and other purposes.
    Type: Application
    Filed: December 20, 2023
    Publication date: July 18, 2024
    Inventor: Rafael Vazquez Gomez
  • Patent number: 11858834
    Abstract: Plant growth and energy storage is supported by complicated bio-electro-chemical processes causing the intake of water and nutrients from the ground. These processes are affected by adaptations such as root structure and genetic characteristics that facilitate a plant species' survival in its native regions. Disclosed are methods for altering the water and nutrient intake through electrical alignment of molecules with dipole characteristics and ionized molecules, and apparatus for performing the disclosed methods. Through the disclosed invention, the capacity of water molecules to interact at an electro-chemical level with soil elements can be increased or reduced to guide absorption-transport activity, facilitating optimal plant growth for agricultural and other purposes.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: January 2, 2024
    Inventor: Rafael Vazquez Gomez
  • Patent number: 11013732
    Abstract: Metal complexes comprising a compound of general formula (I) and at least one metal ion, for use in the treatment of diseases related to the accumulation of intracellular deposits and/or diseases related to defective autophagy and/or defective proteasome activity is disclosed. Compositions comprising said metal complexes comprising a compound of general formula (I) and at least one metal ion, for use in the treatment of diseases related to the accumulation of intracellular deposits and/or diseases related to defective autophagy and/or defective proteasome activity are also disclosed.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: May 25, 2021
    Assignee: BIONOS BIOTECH, S.L.
    Inventors: José Luis Mullor Sanjosé, Rafael Vázquez Manrique, David González Fernández
  • Publication number: 20200101062
    Abstract: Metal complexes comprising a compound of general formula (I) and at least one metal ion, for use in the treatment of diseases related to the accumulation of intracellular deposits and/or diseases related to defective autophagy and/or defective proteasome activity is disclosed. Compositions comprising said metal complexes comprising a compound of general formula (I) and at least one metal ion, for use in the treatment of diseases related to the accumulation of intracellular deposits and/or diseases related to defective autophagy and/or defective proteasome activity are also disclosed.
    Type: Application
    Filed: July 3, 2018
    Publication date: April 2, 2020
    Inventors: José Luis MULLOR SANJOSÉ, Rafael VÁZQUEZ MANRIQUE, David GONZÁLEZ FERNÁNDEZ
  • Publication number: 20190380279
    Abstract: Plant growth and energy storage is supported by complicated bio-electro-chemical processes causing the intake of water and nutrients from the ground. These processes are affected by adaptations such as root structure and genetic characteristics that facilitate a plant species' survival in its native regions. Disclosed are methods for altering the water and nutrient intake through electrical alignment of molecules with dipole characteristics and ionized molecules, and apparatus for performing the disclosed methods. Through the disclosed invention, the capacity of water molecules to interact at an electro-chemical level with soil elements can be increased or reduced to guide absorption-transport activity, facilitating optimal plant growth for agricultural and other purposes.
    Type: Application
    Filed: May 31, 2019
    Publication date: December 19, 2019
    Inventor: Rafael Vazquez Gomez
  • Patent number: 10480012
    Abstract: Hybrid proteins with cytochrome P450 activity and which are encapsulated in a nanocapsid (nanoparticles charged with cytochrome P450 activity) are designed and synthesized, these hybrid proteins being immunologically inert and recognized by breast cancer cells.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: November 19, 2019
    Assignee: UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO
    Inventors: Rafael Vazquez Duhalt, Lorena Paulina Sanchez Sanchez
  • Publication number: 20180327780
    Abstract: Hybrid proteins with cytochrome P450 activity and which are encapsulated in a nanocapsid (nanoparticles charged with cytochrome P450 activity) are designed and synthesized, these hybrid proteins being immunologically inert and recognized by breast cancer cells.
    Type: Application
    Filed: May 26, 2016
    Publication date: November 15, 2018
    Inventors: Rafael Vazquez Duhalt, Lorena Paulina Sanchez Sanchez
  • Patent number: 9087452
    Abstract: A method of detecting conflicts between aircraft passing through managed airspace, and to resolving the detected conflicts strategically. The method may include obtaining intended trajectories of aircraft through the airspace and time constraints corresponding to time of arrival at specified locations, detecting conflicts in the intended trajectories, forming a set of the conflicted aircraft, calculating one or more revised trajectories for the conflicted aircraft such that the conflicts are resolved and the time constraints met, and advising the conflicted aircraft subject to revised trajectories of the revised trajectories.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: July 21, 2015
    Assignee: The Boeing Company
    Inventors: Isabel del Pozo de Poza, Miguel Vilaplana, Alfonso Valenzuela, Rafael Vazquez, Damian Rivas
  • Publication number: 20140248628
    Abstract: The present invention is referred to two human nucleic 5 acids that comprise sequences encoding two new isoforms of the human somatostatin receptor type 5 originated by alternative splicing, named sst5B and sst5C, with possible involvement in tumor processes. In addition, the invention is referred to oligonucleotide pairs allowing 10 their differential detection in several tissues using the PCR technique.
    Type: Application
    Filed: April 2, 2014
    Publication date: September 4, 2014
    Applicant: UNIVERSIDAD DE CORDOBA
    Inventors: Mario Durán Prado, Antonio Jesús Martinez Fuentes, Rafael Vazquez Martinez, Socorro Garcia Navarro, Maria del Mar Malagón Poyato, Justo Pastor Castaño Fuentes, Francisco Gracia-Navarro
  • Publication number: 20130317733
    Abstract: A method of detecting conflicts between aircraft passing through managed airspace, and to resolving the detected conflicts strategically. The method may include obtaining intended trajectories of aircraft through the airspace and time constraints corresponding to time of arrival at specified locations, detecting conflicts in the intended trajectories, forming a set of the conflicted aircraft, calculating one or more revised trajectories for the conflicted aircraft such that the conflicts are resolved and the time constraints met, and advising the conflicted aircraft subject to revised trajectories of the revised trajectories.
    Type: Application
    Filed: May 24, 2013
    Publication date: November 28, 2013
    Applicant: The Boeing Company
    Inventors: Isabel del Pozo de Poza, Miguel Vilaplana, Alfonso Valenzuela, Rafael Vazquez, Damian Rivas
  • Patent number: 8354273
    Abstract: The present invention concerns two human nucleic acids comprising sequences which code two novel isoforms of human somatostatin receptor type 5 produced by alternative adjustment, called sst5B and sst5C and with possible uses in tumoral processes. Additionally, the invention concerns oligonucleotide pairs used for the differential detection of said isoforms by means of the PCR technique in different tissues.
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: January 15, 2013
    Assignee: Universidad de Cordoba
    Inventors: Mario Durán Prado, Antonio Jesús Martínez Fuentes, Rafael Vazquez Martínez, Socorro García Navarro, María del Mar Malagón Poyato, Justo Pastor Castaño Fuentes, Francisco Garcia-Navarro
  • Publication number: 20120003252
    Abstract: The present invention concerns two human nucleic acids comprising sequences which code two novel isoforms of human somatostatin receptor type 5 produced by alternative adjustment, called sst5B and sst5C and with possible uses in tumoral processes. Additionally, the invention concerns oligonucleotide pairs used for the differential detection of said isoforms by means of the PCR technique in different tissues.
    Type: Application
    Filed: October 17, 2007
    Publication date: January 5, 2012
    Inventors: Mario Durán Prado, Antonio Jesús Martínez Fuentes, Rafael Vazquez Martínez, Socorro García Navarro, María del Mar Malagón Poyato, Justo Pastor Castaño Fuentes, Francisco Garcia-Navarro
  • Patent number: 7923015
    Abstract: A method for visualizing an active synapse wherein said method comprises: (a) exposing cells forming the active synapse to a biomarker comprising at least fragment C of tetanus toxin and a reporter protein; and (b) visualizing the biomarker; wherein the accumulation of the biomarker into dendritic spines of the cells allows visualization of an active synapse. Also, a method for screening molecules capable of modulating synapse activity is provided. A kit useful for the early diagnosis of neurodegenerative disease comprises a biomarker comprising at least fragment C of tetanus toxin and a reporter protein.
    Type: Grant
    Filed: April 6, 2004
    Date of Patent: April 12, 2011
    Assignees: Institut Pasteur, Centre Nationale de la Recherche Scientifique
    Inventors: Rafael Vazquez-Martinez, Philippe Brulet
  • Patent number: 7581861
    Abstract: The object of the invention is a closure device able to be mounted on an opening in the housing of a lighting/signalling device for a motor vehicle of the headlight type. This device comprises a rigid cover on which a movable flap is able to slide over a given travel between an open position and a closed position. The movable flap being provided with mechanical locking means cooperating when it is in the closed position with complementary means present on the housing on or close to the periphery of the opening in order to ensure the locking of the cover in abutment against the housing.
    Type: Grant
    Filed: March 21, 2006
    Date of Patent: September 1, 2009
    Assignee: Valeo Vision
    Inventors: Manuel Gomez Ramirez, Rafael Vazquez Quesada
  • Publication number: 20080070877
    Abstract: The present invention includes the selection of a particular species of Epilobium, and the production of an efficacious Epilobium extract. The method of extraction utilized in the present invention includes the selection and separation of parts of Epilobium Parviflorum plant to be used, excluding the use of solid stems and roots. Once selected, the plant parts are combined with a solvent and water for the extraction process. In one embodiment of the present invention, the Epilobium plant parts are combined at room temperature, such as between 71 to 81 degrees (F.) or 20 to 25 degrees (C.), with 196 proof Sugar Cane Alcohol (without denaturalization process), stirred, and allowed to rest, such as for 72 hours. Next, an additional amount of Sugar Cane Alcohol and water is added, stirred, and allowed to rest, such as for 24 hours. Next, water is added, stirred, and allowed to rest, such as for 48 hours; and this step may be repeated.
    Type: Application
    Filed: September 7, 2007
    Publication date: March 20, 2008
    Inventors: Rafael Vazquez Gomez, Robert Jacquet
  • Publication number: 20070092449
    Abstract: A method for visualizing an active synapse wherein said method comprises: (a) exposing cells forming the active synapse to a biomarker comprising at least fragment C of tetanus toxin and a reporter protein; and (b) visualizing the biomarker; wherein the accumulation of the biomarker into dendritic spines of the cells allows visualization of an active synapse. Also, a method for screening molecules capable of modulating synapse activity is provided. A kit useful for the early diagnosis of neurodegenerative disease comprises a biomarker comprising at least fragment C of tetanus toxin and a reporter protein.
    Type: Application
    Filed: October 5, 2006
    Publication date: April 26, 2007
    Inventors: Rafael Vazquez-Martinez, Philippe Brulet
  • Publication number: 20060213787
    Abstract: The object of the invention is a closure device able to be mounted on an opening in the housing of a lighting/signalling device for a motor vehicle of the headlight type. This device comprises a rigid cover on which a movable flap is able to slide over a given travel between an open position and a closed position. The movable flap being provided with mechanical locking means cooperating when it is in the closed position with complementary means present on the housing on or close to the periphery of the opening in order to ensure the locking of the cover in abutment against the housing.
    Type: Application
    Filed: March 21, 2006
    Publication date: September 28, 2006
    Inventors: Manuel Gomez Ramirez, Rafael Vazquez Quesada
  • Publication number: 20050060761
    Abstract: A method for visualizing an active synapse wherein said method comprises: (a) exposing cells forming the active synapse to a biomarker comprising at least fragment C of tetanus toxin and a reporter protein; and (b) visualizing the biomarker; wherein the accumulation of the biomarker into dendritic spines of the cells allows visualization of an active synapse. Also, a method for screening molecules capable of modulating synapse activity is provided. A kit useful for the early diagnosis of neurodegenerative disease comprises a biomarker comprising at least fragment C of tetanus toxin and a reporter protein.
    Type: Application
    Filed: April 6, 2004
    Publication date: March 17, 2005
    Inventors: Rafael Vazquez-Martinez, Philippe Brulet
  • Publication number: 20040099562
    Abstract: A tablet containing system that helps prevent tablet-portions from interfering with the toilet flushing mechanism, can be tethered within the toilet bowl, and allows for tablet-portions to be easily removed from the toilet tank.
    Type: Application
    Filed: November 21, 2003
    Publication date: May 27, 2004
    Inventor: Rafael A. Vazquez
  • Patent number: 6461859
    Abstract: The invention relates to a method of removing thiophenic and organosulfide compounds from a fossil fuel comprising the steps of contacting the fossil fuel with hemoproteins, which oxidize the sulfur containing compounds to sulfoxides and sulfones in a reaction system containing organic solvent or not, and followed by a distillation step in which sulfoxides and sulfones are removed from the fuel. Preferred biocatalysts include hemoproteins such as chloroperoxidase from Caldariomyces fumago, and peroxidases and cytochromes from animal, plant or microbial cells. The hemoprotein biocatalyst can be contacted with the fossil fuel in free or immobilized forms. The reaction can be carried out in the presence of the fuel alone or with addition of any organic solvent. The biocatalytically oxidized fuel is then distilled in order to eliminate the heavy fraction which contains most of oxidized organosulfur compounds.
    Type: Grant
    Filed: September 9, 1999
    Date of Patent: October 8, 2002
    Assignees: Instituto Mexicano del Petroleo, Universidad Nacional Autonoma de Mexico
    Inventors: Rafael Vazquez Duhalt, Maria del Pilar Bremauntz, Eduardo Barzana, Raunel Tinoco