Patents by Inventor Rafal Kruszynski

Rafal Kruszynski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-inflammatory zinc(II) complex
    Patent number: 10144748
    Abstract: The anti-inflammatory zinc(II) complex, viz., crystalline bis(chloro)-(N,N?-(2,2-dimethylpropane-1,3-diyl)bis(1-(2-chlorophenyl)-methanimine))-zinc zinc(II) complex, may be used as an anti-inflammatory. The compound has the formula: This complex is prepared by reaction of a Schiff base, namely, N,N?-bis(2-chlorobenzylidene)-2,2-dimethylpropane-1,3-diamine, with zinc chloride in alcohol to form a precipitate, which is removed by filtration, followed by slow evaporation of the filtrate to obtain the crystalline product. In vivo testing showed that the above zinc(II) complex exhibited good anti-inflammatory effect. It is thought that the present zinc-based anti-inflammatory avoids the gastrointestinal side effects of conventional NSAIDs due to the coordinated zinc complex.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: December 4, 2018
    Assignee: King Saud University
    Inventors: Mohammad Azam, Saud Ibrahim Al-Resayes, Faiyaz Shakeel, Agata Trzesowska-Kruszynska, Rafal Kruszynski