Patents by Inventor Raffaello Fusco

Raffaello Fusco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 1-alkyl-3-carboxy-4-cinnolones
    Patent number: 4956460
    Abstract: A process for the preparation of 1-alkyl-3-carboxy-4-cinnolones of formula I ##STR1## wherein R and R.sub.1 are electron donor groups and R.sub.3 is an alkyl group, starting from an amine of formula II ##STR2## which is subjected to the following transformations; (1) diazotation;(2) coupling with a cyanoacetic ester;(3) alkylation of the arylhydrazone obtained in (2);(4) hydrolysis of the ester and conversion into acyl chloride;(5) intramolecular cyclization;(6) hydrolysis of the nitrile residue.
    Type: Grant
    Filed: March 23, 1988
    Date of Patent: September 11, 1990
    Assignee: Industria Chimica Profarmaco S.p.A.
    Inventors: Raffaello Fusco, Fulvio L. Piselli, Pier M. Boschi
  • Highly soluble antibacterially active organic salts of pyridobenzothiazines
    Patent number: 4910196
    Abstract: New highly soluble antibacterially active salts of pyridobenzothiazines with organic acids are described.In particular, organic salts of 9-fluoro-10[N-(4'-methyl)piperazinyl]-7-oxo-2,3-dihydro-7H-pyrido[1,2,3][1 ,4]-benzothiazine-6-carboxylic acid are prepared with an acid chosen from the group consisting of methanesulphonic acid, ethanesulphonic acid, n-dodecanesulphonic acid, p-toluenesulphonic acid, 1-actadecanesulphonic acid, 2-chloro-ethanesulphonic acid, 2-bromo-ethanesulphonic acid, 3-hydroxy-propanesulphonic acid, citric acid, malonic acid, gluconic acid, malic acid, lactic acid and L-tartaric acid.A new process is also described for preparing said salts from 2,3,4-trichloronitrobenzene, by way of a 2-fluoro-3-chloro-4-mercapto derivative of the nitrobenzene and cyclizing the corresponding amino derivative.
    Type: Grant
    Filed: June 22, 1987
    Date of Patent: March 20, 1990
    Assignee: Mediolanum Farmaceutici Srl
    Inventors: Patrizia Terni, Pier L. Rugarli, Stefano Maiorana, Pier G. Pagella, Raffaello Fusco
  • Method for the purification of sewage waters which contain organic compounds of an anionic character
    Patent number: 4178242
    Abstract: Bisisothiouronium salts are disclosed, which are extremely useful in the depollution of water in which the pollutants are dyestuffs and generally anionic compounds difficult to precipitate. Precipitation with bisisothiouronium salts according to the invention occurs, conversely, very easily.
    Type: Grant
    Filed: August 21, 1978
    Date of Patent: December 11, 1979
    Assignee: Anic S.p.A.
    Inventor: Raffaello Fusco
  • Method for purifying waste waters which contain anionic-type organic compounds
    Patent number: 4000069
    Abstract: In waste-water-treatment, the improvement consisting in causing the precipitation of anionic pollutants by adding to the sewage an aqueous solution of a bis-triarylphosphonium salt. A number of different chemical formulas for such salts are disclosed. It becomes possible to recover dyestuffs from dyeing baths in the textile industries, while solving a severe pollution-preventing problem.
    Type: Grant
    Filed: February 3, 1976
    Date of Patent: December 28, 1976
    Assignee: Anic S.p.A.
    Inventor: Raffaello Fusco