Abstract: Systems for reducing reduce downtime include industrial machines, sensor(s) associated therewith, edge agent(s), central controller(s), and display(s). The sensor(s) detect operational parameters (e.g., error condition) of the industrial machines associated therewith. The edge agent(s) receive information (e.g., logging messages) from the industrial machines and/or information from the sensors. The central controller(s). The central controllers receive and transform the information into standardized logging messages that are formatted identically, analyze the standardized logging messages to determine occurrence(s) of a current or anticipated error condition for any of the industrial machines, and transmit an alert and/or notification to the display(s) so users can take corrective action to ensure proper operation of the industrial machines. Such a system can be used in performing a corresponding method for reducing downtime associated with current or anticipated error conditions of such industrial machines.

Abstract: An inhaler device for dispensing medicament comprising: a dispenser flow channel leading to a mouthpiece, a medicament holder, and a mesh part placed in the dispenser flow channel between the medicament holder and the mouthpiece, wherein said mesh part is made of a Polyoxymethylene.

Abstract: The present invention relates to sustained release dosage form of Ranolazine or pharmaceutically acceptable salt(s), polymorph(s), solvate(s), hydrate(s), enantiomer(s) thereof which comprises a combination of at least two pH-dependent binders and optionally one or more pharmaceutically acceptable excipient(s).