Abstract: Novel 2-(substituted benzyl)-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-ones and 4-fluoro-N-(4-oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)benzamide compounds, a method of synthesizing said compounds, a pharmaceutical composition comprising said compounds and a suitable carrier, and a method of using the compounds. The 2-(substituted benzyl)-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-ones and 4-fluoro-N-(4-oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)benzamide compounds, identified as COX-2 inhibitors, are useful as anti-inflammatory and pain agents.

Abstract: In various embodiments, a process for providing a dynamic Web component with configurable content includes receiving an instruction to move a component from a first portion of a user interface to a second portion of the user interface for application on the second portion of the user interface, wherein the second portion is configured to receive an input from a user. The process includes programmatically analyzing content of the second portion to select a machine learning model, and determining, for the user, the input to the second portion using the selected machine learning model.

Abstract: A method for preventing a collision between a first object and a second object using a camera. The method includes capturing images of the first object and the second object using the camera, accessing a database of point clouds, and identify a first point cloud corresponding to the first object and a second point cloud corresponding to the second object within the database of point clouds, where the first point cloud corresponds to the first object being a person. The method further includes calculating a distance between the first object and the second object and comparing the distance to a threshold. The method further includes generating a notification when the distance is below the threshold.

Abstract: Various methods and systems are provided for automatically recommending one or more radiology protocols based on an imaging examination order which includes both structured and unstructured data. In one example, a method includes receiving an imaging examination order requesting an imaging examination, wherein the imaging examination order comprises structured data and unstructured text, converting the unstructured text into one or more feature vectors, mapping the structured data and the one or more feature vectors to a standardized radiology protocol representation using an imaging examination order classifier, and mapping the standardized radiology protocol representation to a site-specific radiology protocol using a site-specific radiology protocol translator.

Abstract: An indication associated with a web component of a web content page is received from a client. The indication indicates that a version of the web component is not available at the client. While providing the web content page to the client, the web component is updated to generate an updated web component. In response to the indication, the updated web component is obtained among a plurality of web components. The updated web component for the web content page is provided to the client.

Abstract: A method for planning a moving path of a machine table in a medical imaging system is described. The method includes determining a to-be-scanned region in an object 3D point cloud of the object based on a scanning plan, determining a center of gravity of the to-be-scanned region and a height of the center of gravity, determining a target height for positioning the machine table based on the height of the center of gravity and a central height of the scanning space, so that the height of the center of gravity is equal to the central height of the scanning space when the machine table is positioned at the target height, and planning the moving path of the machine table based on the determined target height. The scanning plan comprises positioning information of the to-be-scanned region relative to the object.

Abstract: The current disclosure provides methods and systems for rapidly and consistently determining medical image quality metrics following acquisition of a diagnostic medical image. In one embodiment, the current disclosure teaches a method for determining an image quality metric by, acquiring a medical image of an anatomical region, mapping the medical image to a positional attribute of an anatomical feature using a trained deep neural network, determining an image quality metric based on the positional attribute of the anatomical feature, determining if the image quality metric satisfies an image quality criterion, and displaying the medical image, the image quality metric, and a status of the image quality criterion via a display device. In this way, a diagnostic scanning procedure may be expedited by providing technicians with real-time insight into quantitative image quality metrics.

Abstract: A web content page is provided, wherein the web content page is configured to dynamically provide a new web component streamed from a server after the web content page has been initially loaded by a client. An indication associated with a desired web component is received. The desired web component among a plurality of web components developed on a platform-as-a-service environment separately from the web content page is obtained. The desired web component is streamed to the web content page.

Abstract: A method for generating an object 3D point cloud in a medical imaging system comprising a machine table and a scanning device comprises: extracting a valid 3D point cloud in a valid region where the machine table is located from a global 3D point cloud based on a current height of the machine table and boundary information of the machine table, wherein the global 3D point cloud comprises 3D point clouds of an object and a surrounding environment thereof, and the object 3D point cloud is comprised in the valid 3D point cloud; and removing an environment 3D point cloud of the surrounding environment from the valid 3D point cloud to obtain the object 3D point cloud, wherein the surrounding environment comprises at least part of the machine table. In some embodiments, a moving path of the machine table in the medical imaging system is planned using the object 3D point cloud. In some embodiments, collision prediction of the object is performed in the medical imaging system using the object 3D point cloud.

Abstract: Compounds for treating a microbial infection and/or tuberculosis and, particularly, antimicrobial and/or antitubercular compounds that are 3-cyano 4,5-diphenyl furan-2-carboxamides and their use as antimicrobial and/or antitubercular agents are provided.

Abstract: Methods of inhibiting cyclooxygenase enzyme-2 (COX-2) using thieno[2,3-d]pyrimidine compounds. These methods can be effective for treating inflammation, pain, or any other COX-2 mediated disorder.

Abstract: Compounds for treating tuberculosis and, particularly, antitubercular compounds that are 1-substituted benzoyl-4-bromopyrrolo[1,2-a]quinoline-3-carboxylate derivatives and their use as antitubercular agents are provided.

Abstract: Benzylidene derivatives of fenobam compounds, a method of synthesizing said compounds, a pharmaceutical composition comprising said compounds and a suitable carrier, and a method of using the compounds. The benzylidene derivatives of fenobam, identified as COX-1 and COX-2 inhibitors, are useful as anti-inflammatory agents.

Abstract: A web content page is provided, wherein the web content page is configured to dynamically provide a new web component streamed from a server after the web content page has been initially loaded by a client. An indication associated with a desired web component is received. The desired web component among a plurality of web components developed on a platform-as-a-service environment separately from the web content page is obtained. The desired web component is streamed to the web content page.

Abstract: Techniques relating to a pipeline for intelligent text annotation of medical reports via artificial intelligence based Natural Language Processing workflows are provided. One or more embodiments described herein can regard a computer-implemented system comprising a memory that can store computer-executable components. The computer-implemented system can comprise a processor, operatively coupled to the memory, that executes the computer-executable components stored in the memory.

Abstract: Systems and techniques that facilitate real-time and/or offline de-identification of facial regions from regular and/or occluded color video streams obtained during diagnostic medical procedures are provided. A detection component can generate a bounding box substantially around a person in a frame of a video stream, can generate a heatmap showing key points or anatomical masks of the person based on the bounding box, and can localize a face or facial region of the person based on the key points or anatomical masks. An anonymization component can anonymize pixels in the frame that correspond to the face or facial region. A tracking component can track the face or facial region in a subsequent frame based on a structural similarity index between the frame and the subsequent frame being above a threshold.

Abstract: Various methods and systems are provided for longitudinal presentation of patient information. In one example, a computing device comprises a display screen, the computing device being configured to display on the screen a timeline of patient medical information including a plurality of symbols representing the patient medical information, wherein a symbol of the plurality of symbols is selectable to launch a details panel and enable a report that references the displayed patient medical information to be seen within the timeline, and wherein the symbol is displayed while the details panel is in an un-launched state.

Abstract: A method for preventing a collision between a first object and a second object using a camera. The method includes capturing images of the first object and the second object using the camera, accessing a database of point clouds, and identify a first point cloud corresponding to the first object and a second point cloud corresponding to the second object within the database of point clouds, where the first point cloud corresponds to the first object being a person. The method further includes calculating a distance between the first object and the second object and comparing the distance to a threshold. The method further includes generating a notification when the distance is below the threshold.

Abstract: A method for monitoring a patient in a bed using a camera. The method includes identifying a boundary of the bed using data from the camera, identifying parts of the patient using data from the camera, and determining an orientation of the patient using the parts identified for the patient. The method further includes monitoring movement of the patient using the parts identified for the patient and computing a departure score indicating the likelihood of the patient departing the bed based on the orientation of the patient and the movement of the patient. The method further includes comparing the departure score to a predetermined threshold and generating a notification when the departure score exceeds the predetermined threshold.

Abstract: Systems and methods for automated patient anatomy and orientation identification using an artificial intelligence (AI) based deep learning module are provided. The method comprises positioning a subject over a table of a magnetic resonance imaging (MRI) system and wrapping at least one radiofrequency (RF) imaging coil over the subject. The method comprises obtaining a plurality of depth images, color images and infrared images of the subject using a three-dimensional (3D) depth camera and identifying the table boundary of the MRI system using the images obtained by the 3D camera. The method further comprises identifying a location of the subject over the table to determine if the subject is positioned within the table boundary of the MRI system and identifying a plurality of key anatomical points or regions corresponding to a plurality of organs of the subject body.