Abstract: Certain embodiments of the present invention provide systems and methods of improved medical device navigation. Certain embodiments include acquiring a first image of a patient anatomy, a second image of patient anatomy, and creating a registered image based on the first and second images. Certain preferred embodiments teach systems and methods of automated image registration without the use of fiducial markers, headsets, or manual registration. Thus the embodiments teach a simplified method of image registration that allows a medical device to be navigated within a patient anatomy. Furthermore, the embodiments teach navigating a medical device in a patient anatomy with reduced exposure to ionizing radiation. Additionally, the improved systems and methods of image registration provide for improved accuracy of the registered images.

Abstract: An integrated medical navigation system for use with at least one electromagnetic sensor and at least one device that may comprise at least one electromagnetic field generator coupled to the at least one device, a navigation interface configured to receive digitized signals from the at least one electromagnetic sensor, a tracker module configured to determine a location of the at least one device based on the received digitized signals, and a navigation module configured to receive the location determined by the tracking module, and register the location to acquired patient image data.