Patents by Inventor Rahamim Ben-Yosef

Rahamim Ben-Yosef has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant fusion protein and polynucleotide construct for immunotoxin production
    Patent number: 8597655
    Abstract: The present invention relates to a polynucleotide construct encoding a fusion protein consisting of a domain which binds the immunoglobulin Fc region, genetically fused to a truncated form of Pseudomonas exotoxin A (PE). In particular, the invention discloses the fusion protein, ZZ-PE38, and further provides immunotoxins, formed from complexes of the fusion protein with antibodies for targeted cell killing.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: December 3, 2013
    Assignees: Ramot at Tel-Aviv University Ltd., The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Itay Barnea, Itai Benhar, Rahamim Ben-Yosef, Akiva Vexler
  • RECOMBINANT FUSION PROTEIN AND POLYNUCLEOTIDE CONSTRUCT FOR IMMUNOTOXIN PRODUCTION
    Publication number: 20120076780
    Abstract: The present invention relates to a polynucleotide construct encoding a fusion protein consisting of a domain which binds the immunoglobulin Fc region, genetically fused to a truncated form of Pseudomonas exotoxin A (PE). In particular, the invention discloses the fusion protein, ZZ-PE38, and further provides immunotoxins, formed from complexes of the fusion protein with antibodies for targeted cell killing.
    Type: Application
    Filed: September 22, 2011
    Publication date: March 29, 2012
    Inventors: Itay Barnea, Itai Benhar, Rahamim Ben-Yosef, Akiva Vexler