Patents by Inventor Rahman A. Ismail

Rahman A. Ismail has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8076148
    Abstract: The present invention relates to a cytochrome c-reporter fusion protein construct comprising a modified cytochrome c protein which targets the mitochondria and has a reduced ability to induce apoptosis in a living cell. The invention also relates to nucleic acid constructs encoding such protein fusions and cells stably transfected with such constructs. The stably transfected cells of the invention can be used in assays to detect apoptosis.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: December 13, 2011
    Assignee: GE Healthcare UK Limited
    Inventors: Simon L. Stubbs, Michael J. Francis, Adrian Cushing, Rahman A. Ismail
  • Publication number: 20090053748
    Abstract: The present invention relates to a a cytochrome c-reporter fusion protein construct comprising a modified cytochrome c protein which targets the mitochondria and has a reduced ability to induce apoptosis in a living cell. The invention also relates to nucleic acid constructs encoding such protein fusions and cells stably transfected with such constructs. The stably transfected cells of the invention can be used in assays to detect apoptosis.
    Type: Application
    Filed: December 17, 2004
    Publication date: February 26, 2009
    Inventors: Simon L. Stubbs, Michael J. Francis, Adrian Cushing, Rahman A. Ismail