Patents by Inventor Raimund Sprenger

Raimund Sprenger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for determining the presence of at least one allele of a GSTT1 deletion mutant
    Patent number: 6723508
    Abstract: Method for detecting the presence of at least one single allele of a deletion mutant, specially as PCR assay for detecting the presence of at least one GST1*0 allele wherein a PCR is performed with two primers, of which one stems from the sequence upstream of the deletion area, and the other stems from the sequence downstream of the deletion area and wherein the production of the corresponding DNA fragment in the PCR is checked. Useful for testing of patients to check whether they are susceptible to toxins or resistant or overly sensitive to certain therapeutic agents or belonging to risk groups.
    Type: Grant
    Filed: February 22, 2001
    Date of Patent: April 20, 2004
    Assignee: Epidauros Biotechnologie AG
    Inventors: Raimund Sprenger, Robert Schlagenhaufer, Ulrich Brinkmann, Reinhold Kerb
  • Method for detecting the presence of at least one single allele of a deletion mutant
    Publication number: 20020022225
    Abstract: Method for detecting the presence of at least one single allele of a deletion mutant, specially as PCR assay for detecting the presence of at least one GST1*0 allele wherein a PCR is performed with two primers, of which one stems from the sequence upstream of the deletion area, and the other stems from the sequence downstream of the deletion area and wherein the production of the corresponding DNA fragment in the PCR is checked. Useful for testing of patients to check whether they are susceptible to toxins or resistant or overly sensitive to certain therapeutic agents or belonging to risk groups.
    Type: Application
    Filed: February 22, 2001
    Publication date: February 21, 2002
    Inventors: Raimund Sprenger, Robert Schlagenhaufer, Ulrich Brinkmann, Reinhold Kerb
  • Positive-negative selection for homologous recombination
    Patent number: 6284541
    Abstract: The invention concerns a method for the introduction of a foreign DNA into the genome of a target cell by homologous recombination as well as for the homologous recombination of suitable DNA constructs.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: September 4, 2001
    Assignee: Roche Diagnostics GmbH
    Inventors: Johannes Auer, Raimund Sprenger, Konrad Honold