Abstract: The present invention pertains inter alia to a method for analyzing a sample comprising biomolecules, which comprises the following steps: A a) lysing the sample to provide a lysed sample and optionally clearing the lysed sample; b) contacting at least a portion of the lysed sample with a dry composition comprising reagents for performing the analytical method, thereby providing a reconstituted composition; c) performing an analytical method using the reconstituted composition; or B a) contacting the sample with a lysis solution thereby providing a lysis mixture; b) using the lysis mixture to reconstitute a dry composition comprising reagents for performing the analytical method, thereby providing a reconstituted composition; c) performing an analytical method using the reconstituted composition, wherein the reconstituted composition is optionally cleared and wherein subsequent to step b) at least one step is performed which supports the lysis of the sample.

Abstract: The invention relates to a system comprising a rotary valve and an actuating device for the rotary valve. The invention further relates to a related flow system having a rotary valve. The flow system is in particular a micro-flow system. The system comprises at least two separate components, wherein the one component is a rotary valve comprising a hollow cylindrical mount (2), a cylindrical valve body (5) located in the mount, and openings (3a, 3b, 3c, 3d) for at least two channels at the bottom of the mount (2). The other component comprises an actuating device (9) that is provided with pressing means, by means of which the valve body (5) can be pressed to the bottom of the mount (2).

Abstract: The present invention relates to a method for amplifying and detecting nucleic acid sequences in a reaction cartridge comprising, (i) providing a sample comprising at least one nucleic acid molecule, (ii) in a first reaction chamber of the cartridge providing reagents for an amplification reaction, (iii) mixing the sample with the amplification reagents, (iv) amplifying the at least one nucleic acid in the first reaction chamber of the cartridge, (v) transferring at least parts of the amplification reaction into a second and third reaction chamber of the cartridge each comprising a probe set and performing a melting point analysis in order to determine which of the probes has specifically bound a nucleic acid.

Abstract: The present invention pertains inter alia to a method for analysing a sample comprising biomolecules, which comprises the following steps: A a) lysing the sample to provide a lysed sample and optionally clearing the lysed sample; b) contacting at least a portion of the lysed sample with a dry composition comprising reagents for performing the analytical method, thereby providing a reconstituted composition; c) performing an analytical method using the reconstituted composition; or B a) contacting the sample with a lysis solution thereby providing a lysis mixture; b) using the lysis mixture to reconstitute a dry composition comprising reagents for performing the analytical method, thereby providing a reconstituted composition; c) performing an analytical method using the reconstituted composition, wherein the reconstituted composition is optionally cleared and wherein subsequent to step b) at least one step is performed which supports the lysis of the sample.

Abstract: The present invention relates to a reaction vessel for crystallization of a sample from a solution and a covering foil and an arrangement for mounting the covering foil.

Abstract: The present invention relates to a reaction vessel for crystallization of a sample from a solution and a covering foil and an arrangement for mounting the covering foil.

Abstract: The invention relates to a system comprising a rotary valve and an actuating device for the rotary valve. The invention further relates to a related flow system having a rotary valve. The flow system is in particular a micro-flow system. The system comprises at least two separate components, wherein the one component is a rotary valve comprising a hollow cylindrical mount (2), a cylindrical valve body (5) located in the mount, and openings (3a, 3b, 3c, 3d) for at least two channels at the bottom of the mount (2). The other component comprises an actuating device (9) that is provided with pressing means, by means of which the valve body (5) can be pressed to the bottom of the mount (2).

Abstract: The present invention relates to a method for amplifying and detecting nucleic acid sequences in a reaction cartridge comprising the following steps, (i) providing a sample comprising at least one nucleic acid molecule, (ii) in a first reaction chamber of the cartridge providing reagents for an amplification reaction, (iii) mixing the sample with the amplification reagents, (iv) amplifying the at least one nucleic acid in the first reaction chamber of the cartridge, (v) transferring at least parts of the amplification reaction into a second and third reaction chamber of the cartridge each comprising a probe set, wherein (a) each probe set consists of at least three probes, (b) each of the probes is specific for a nucleic acid sequence, (c) there are at least two probes in each set which carry an identical label, (d) each of the probes in a given probe set that carries an identical label has a melting temperature (Tm) which differs by more than 2° C.

Abstract: The present invention relates to a reaction vessel for crystallization of a sample from a solution and a covering foil and an arrangement for mounting the covering foil (FIG. 1).