Abstract: The invention relates to the providing of hydrophobic and hydrophilic polymer-based hollow fiber membranes containing a water-insoluble antioxidant; in particular, the invention relates to the providing of hollow fiber membranes for the extracorporeal treatment of blood, wherein the hollow fiber membranes have improved biocompatibility relative to treatment blood, in particular improved complement activation and lower platelet loss vis-à-vis treatment blood. At the same time, the elution of hydrophilic polymers from the lumen of the hollow fiber membrane is reduced.

Abstract: The invention relates to the providing of hydrophobic and hydrophilic polymer-based hollow fiber membranes containing a water-insoluble antioxidant; in particular, the invention relates to the providing of hollow fiber membranes for the extracorporeal treatment of blood, wherein the hollow fiber membranes have improved biocompatibility relative to treatment blood, in particular improved complement activation and lower platelet loss vis-à-vis treatment blood. At the same time, the elution of hydrophilic polymers from the lumen of the hollow fiber membrane is reduced.

Abstract: The invention relates to the providing of hydrophobic and hydrophilic polymer-based hollow fiber membranes containing a water-insoluble antioxidant; in particular, the invention relates to the providing of hollow fiber membranes for the extracorporeal treatment of blood, wherein the hollow fiber membranes have improved biocompatibility relative to treatment blood, in particular improved complement activation and lower platelet loss vis-à-vis treatment blood. At the same time, the elution of hydrophilic polymers from the lumen of the hollow fiber membrane is reduced.

Abstract: The present invention relates to a device for the treatment of blood comprising a solid phase on which a polypeptide is immobilized which is suitable for the inactivation of free nucleic acids. Suitable polypeptides are, for example, deoxyribonucleases, ribonucleases, DNA methyltransferases or cytosine deaminases. The invention further comprises the use of such devices for the treatment of patients suffering from chronic kidney failure, cancer or lupus erythematosus, as well as methods and systems for the treatment of blood, wherein free nucleic acids are inactivated outside the body.

Abstract: The invention relates to the providing of hydrophobic and hydrophilic polymer-based hollow fiber membranes containing a water-insoluble antioxidant; in particular, the invention relates to the providing of hollow fiber membranes for the extracorporeal treatment of blood, wherein the hollow fiber membranes have improved biocompatibility relative to treatment blood, in particular improved complement activation and lower platelet loss vis-à-vis treatment blood. At the same time, the elution of hydrophilic polymers from the lumen of the hollow fiber membrane is reduced.

Abstract: The present invention relates to a device for the treatment of blood comprising a solid phase on which a polypeptide is immobilized which is suitable for the inactivation of free nucleic acids. Suitable polypeptides are, for example, deoxyribonucleases, ribonucleases, DNA methyltransferases or cytosine deaminases. The invention further comprises the use of such devices for the treatment of patients suffering from chronic kidney failure, cancer or lupus erythematosus, as well as methods and systems for the treatment of blood, wherein free nucleic acids are inactivated outside the body.

Abstract: The present invention relates to a membrane, in particular to a hollow fiber membrane comprising a membrane, comprising at least two layers, wherein the at least two layers each comprise at least one layer forming material comprising at least one polymer and the at least two layers differ from each other with respect to the layer forming material, wherein the at least two layers are at least partly covalently and delamination free bonded to each other. The present invention relates furthermore to a method of production of the said membrane as well as to its use.

Abstract: A hollow fiber membrane made of two coextruded layers A and B, wherein layer B has a non-woven type structure having a mesh size of 0.1 to 10 ?m and layer A has a porous structure. A method for producing a membrane according to the invention and the use thereof is also disclosed.

Abstract: The present invention relates to a composite hollow fiber capillary membrane in particular for exploiting the value of dialysate and a method for the production thereof as well as its use in particular in haemo and peritoneal dialysis.

Abstract: The present invention relates to a membrane, in particular to a hollow fiber membrane comprising a membrane, comprising at least two layers, wherein the at least two layers each comprise at least one layer forming material comprising at least one polymer and the at least two layers differ from each other with respect to the layer forming material, wherein the at least two layers are at least partly covalently and delamination free bonded to each other. The present invention relates furthermore to a method of production of the said membrane as well as to its use.

Abstract: The present invention relates to a composite hollow fibre capillary membrane in particular for exploiting the value of dialysate and a method for the production thereof as well as its use in particular in haemo and peritoneal dialysis.

Abstract: The present invention relates to a hollow fiber membrane made of two coextruded layers A and B, wherein layer B has a non-woven type structure having a mesh size of 0.1 to 10 ?m and layer A has a porous structure. The present invention further relates to a method for producing a membrane according to the invention and the use thereof.

Abstract: A hollow fiber membrane made of two coextruded layers A and B, wherein layer B has a non-woven type structure having a mesh size of 0.1 to 10 ?m and layer A has a porous structure. A method for producing a membrane according to the invention and the use thereof is also disclosed.

Abstract: This invention concerns a method of immobilizing a polymer hydrogel on the surface of a corresponding polymer substrate, and a polymer substrate that has a polymer hydrogel layer immobilized, at least in areas, on its surface. The invention has applications particularly as a biocompatible hydrogel coating in the field of medical technology, for example as a coating for surfaces coming in contact with blood, as in hemodialysis, and as a coating for urinary catheters, venous catheters, stents and other surfaces.

Abstract: This invention concerns a method of immobilizing a polymer hydrogel on the surface of a corresponding polymer substrate, and a polymer substrate that has a polymer hydrogel layer immobilized, at least in areas, on its surface. The invention has applications particularly as a biocompatible hydrogel coating in the field of medical technology, for example as a coating for surfaces coming in contact with blood, as in hemodialysis, and as a coating for urinary catheters, venous catheters, stents and other surfaces.