Patents by Inventor Rainer Glockler

Rainer Glockler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microbiological process for the preparation of heteroaromatic carboxylic acids using Alcaligenes faecalis
    Patent number: 5702930
    Abstract: A microbiological process for the preparation of a heteroaromatic carboxylic acid or one of its physiologically tolerated salts of the formulae I or II: ##STR1## wherein R.sub.1 and R.sub.2 are identical or different and each denotes a hydrogen or halogen atom, and X denotes a nitrogen atom or CH--, from a heteroaromatic nitrile of the formulae III or IV, respectively: ##STR2## First, a microorganism, Alcaligenes faecalis (DSM 6335), is cultured in the presence of an inducer, 2-cyanopyridine, and a carbon source such as a dicarboxylic acid, a tricarboxylic acid or a carbohydrate. Substrate III or IV is then reacted with the cultured microorganism. The biotransformation is carried out under anaerobic conditions for compounds of the formula I, and under aerobic conditions for compounds of the formula II.
    Type: Grant
    Filed: June 6, 1996
    Date of Patent: December 30, 1997
    Assignee: Lonza, Ltd.
    Inventors: Andreas Kiener, Jean-Paul Roduit, Rainer Glockler
  • Alcaligenes faecalis strains useful for the microbiological process for the production of 6-hydroxypicolinic acid
    Patent number: 5268294
    Abstract: A microbiological process for the production of 6-hydroxypicolinic acid starting from picolinic acid and/or its salts. The concentration of picolinic acid and/or its salts is selected so that the 6-hydroxypicolinic acid is not further metabolized. The process is performed either by microorganisms of genus Pseudomonas, Bacillus, Alcaligenes, Aerococcus, or Rhodotorula, or with biomass using picolinic acid, which grow with picolinic acid as the sole carbon, nitrogen and energy source.
    Type: Grant
    Filed: May 26, 1992
    Date of Patent: December 7, 1993
    Assignee: Lonza Ltd.
    Inventors: Andreas Kiener, Rainer Glockler, Klaus Heinzmann
  • Microbiological process for the production of 6-hydroxypicolinic acid
    Patent number: 5238830
    Abstract: A microbiological process for the production of 6-hydroxypicolinic acid starting from picolinic acid and/or its salts. The concentration of picolinic acid and/or its salts is selected so that the 6-hydroxypicolinic acid is not further metabolized. The process is performed either by microorganisms of genus Pseudomonas, Bacillus, Alcalioenes, Aerococcus, or Rhodotorula, or with biomass using picolinic acid, which grow with picolinic acid as the sole carbon, nitrogen and energy source.
    Type: Grant
    Filed: March 31, 1992
    Date of Patent: August 24, 1993
    Assignee: Lonza Ltd.
    Inventors: Andreas Kiener, Rainer Glockler, Klaus Heinzmann
  • Microbiological process for the production of 6-hydroxypicolinic acid
    Patent number: 5182197
    Abstract: A microbiological process for the production of 6-hydroxypicolinic acid starting from picolinic acid and/or its salts. The concentration of picolinic acid and/or its salts is selected so that the 6-hydroxypicolinic acid is not further metabolized. The process is performed either by microorganisms of genus Pseudomonas, Bacillus, Alcaligenes, Aerococcus, or Rhodotorula, or with biomass using picolinic acid, which grow with picolinic acid as the sole carbon, nitrogen and energy source.
    Type: Grant
    Filed: February 4, 1992
    Date of Patent: January 26, 1993
    Assignee: Lonza Ltd.
    Inventors: Andreas Kiener, Rainer Glockler, Klaus Heinzmann