Patents by Inventor Rainer H. Müller

Rainer H. Müller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8663692
    Abstract: The invention relates to drug-free or drug-loaded lipid particles of a mixed matrix made of solid and liquid lipids, and to a method for producing highly concentrated lipid particle dispersions of solid-liquid particles having a lipid content of from 30% to 95% or a solids content of from 30% to 95% (lipid and stabilizer), which in contrast to biamphipileic cremes are integer particles, and/or which upon dilution of the highly concentrated particle dispersions with the outer phase result in free-flowable particle dispersions.
    Type: Grant
    Filed: May 8, 2000
    Date of Patent: March 4, 2014
    Assignee: Pharmasol GmbH
    Inventors: Rainer H. Müller, Volkard Jenning, Karsten Mader, Andreas Lippacher
  • Patent number: 8202540
    Abstract: The invention relates to superfine microparticles and nanoparticles and a process for their gentle preparation with exclusion of water or minimization of water and/or exclusion of plasticizers and/or reduced temperature load, in which a matrix material is subjected to a high-pressure homogenization process in an anhydrous or water-poor medium and/or at low temperatures, preferably room temperature (20° C.) and in particular below the freezing point of water, which leads to a gentle particle reduction with minimization of the impairment of the chemical stability of the homogenized material.
    Type: Grant
    Filed: July 10, 2000
    Date of Patent: June 19, 2012
    Assignee: Abbott GmbH & Co., KG
    Inventors: Rainer H. Müller, Karsten Krause, Karsten Mäder
  • Patent number: 6814959
    Abstract: The invention relates to agents with UV radiation-absorbing and/or reflecting action comprising solid, polymorphic, crystal-line or partially crystalline lipid and/or polymer particles, for application to the skin, mucous membranes, scalp, and hair for protection against health-damaging UV radiation and for strengthening the natural skin barrier.
    Type: Grant
    Filed: April 8, 2002
    Date of Patent: November 9, 2004
    Assignee: PharmaSol GmbH
    Inventors: Rainer H. Müller, Sylvia Wissing, Karsten Mäder
  • Patent number: 6770299
    Abstract: The invention relates to particulate active ingredient vehicles which are in the solid aggregate state at room temperature (20° C.) and consist of a pure lipid-drug conjugate (LDC) or a mixture of several LDCs as particle matrix, the bond in the LDC being effected by covalent bonding, electrostatic interactions, dipole moments, dispersion forces, ion interactions, hydrogen bridges and/or hydrophobic interactions.
    Type: Grant
    Filed: January 14, 2002
    Date of Patent: August 3, 2004
    Assignee: PharmaSol GmbH
    Inventors: Rainer H. Müller, Carsten Olbrich