Patents by Inventor Rainer Heintzmann

Rainer Heintzmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9517009
    Abstract: A method for non-invasive observations of a fundus using an ophthalmoscope is provided. The method includes illuminating a retinal region of an eye by projecting an illumination pattern of illumination light onto the retinal region, at least one of detecting a portion of fluorescent light emitted from the retinal region and detecting a portion of illumination light reflected from the retinal region, thereby capturing a series of images of the retinal region at a plurality of different relative positions of the retinal region with respect to the illumination pattern projected onto the retinal region, wherein between the capturing of at least two images of the series the relative position of the retinal region with respect to the illumination pattern projected onto the retinal region is shifted in a non-controlled manner, and processing the captured images to extract a sub-resolution image of the retinal region.
    Type: Grant
    Filed: September 26, 2013
    Date of Patent: December 13, 2016
    Assignees: Ruprecht-Karls-Universit├Ąt Heidelberg, Friedrich-Schiller-Universit├Ąt Jena
    Inventors: Christoph Cremer, Gerrit Best, Roman Amberger, Rainer Heintzmann, Stefan Dithmar, Thomas Ach
  • Publication number: 20150297076
    Abstract: A method for non-invasive observations of a fundus using an ophthalmoscope is provided. The method includes illuminating a retinal region of an eye by projecting an illumination pattern of illumination light onto the retinal region, at least one of detecting a portion of fluorescent light emitted from the retinal region and detecting a portion of illumination light reflected from the retinal region, thereby capturing a series of images of the retinal region at a plurality of different relative positions of the retinal region with respect to the illumination pattern projected onto the retinal region, wherein between the capturing of at least two images of the series the relative position of the retinal region with respect to the illumination pattern projected onto the retinal region is shifted in a non-controlled manner, and processing the captured images to extract a sub-resolution image of the retinal region.
    Type: Application
    Filed: September 26, 2013
    Publication date: October 22, 2015
    Inventors: Christoph Cremer, Gerrit Best, Roman Amberger, Rainer Heintzmann, Stefan Dithmar, Thomas Ach
  • Publication number: 20150260978
    Abstract: A method for obtaining a sub-resolution image of a specimen using a microscope is provided. The method includes projecting an illumination pattern of illumination light onto the specimen, thereby illuminating the specimen, at least one of detecting at least a portion of fluorescent light emitted from the specimen and detecting at least a portion of illumination light reflected from the specimen, thereby capturing a series of images of the specimen at a plurality of different relative positions of the specimen with respect to the illumination pattern projected onto the specimen, wherein between the capturing of at least two images of the series the relative position of the specimen with respect to the illumination pattern projected onto the specimen is shifted in a non-controlled manner, and processing the captured images to extract a sub-resolution image of the specimen.
    Type: Application
    Filed: September 26, 2013
    Publication date: September 17, 2015
    Inventors: Christoph Cremer, Gerrit Best, Roman Amberger, Rainer Heintzmann
  • Publication number: 20120133937
    Abstract: A method of obtaining, in a single exposure, imaging information from an object (16) representative of more than two distinct illumination images, the method comprising the steps of generating first electromagnetic waves (14) at least some of which having spatially modulated polarisation; illuminating the object with the first electromagnetic waves; and capturing second electromagnetic waves (18) emanating from the object.
    Type: Application
    Filed: May 7, 2010
    Publication date: May 31, 2012
    Inventors: Rainer Heintzmann, Kai Wicker
  • Publication number: 20100059696
    Abstract: Embodiments of the invention allow the operation of confocal microscopes with relatively open pinholes (e.g. 1 Airy unit) whilst still giving a significant XY resolution improvement. In addition axial (Z) discrimination or resolution may also be improved. This is achieved by splitting the emitted light path in an interferometric fashion. One of the split beams is then directed inversion which inverts at least one coordinate in image space. The transformed beam and the non-transformed beam are then recombined in an interferometric fashion (i.e. coherently added), which provides an interference effect resulting in increased resolution of the image. Where the embodiments are being used in a confocal application, the resulting combined beam can then be subject to a spatially discriminating means, such as a pinhole, or the like.
    Type: Application
    Filed: February 1, 2008
    Publication date: March 11, 2010
    Inventors: Rainer Heintzmann, Kai Wicker
  • Patent number: 7450238
    Abstract: Disclosed are an array and a method for the spectrally resolving detection of a sample (22) that is illuminated by means of an illuminating radiation (12) by detecting a sample radiation (24) emitted by the sample (22). Said array comprises an illuminating beam path via which illuminating radiation (12) can be delivered to the sample (22) from a lighting source (10, 10?), and an observation beam path via which sample radiation (24) can be delivered to a detector (40) an observation radiation.
    Type: Grant
    Filed: January 26, 2004
    Date of Patent: November 11, 2008
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften E.V.
    Inventors: Walther Rainer Heintzmann, Allen Keith Lidke, Michael Thomas Jovin
  • Patent number: 6909105
    Abstract: A process for obtaining an object image of at least one object (40) is described, wherein at least two partial images of the object (40) are taken under differing object conditions which are formed on the object with spatial patterns, wherein a non-linear dependence of the light detectable from the object point on the object conditions given at the object point exists and the partial images contain different contributions of various space frequency components of the object structure, and the desired object image is determined from the partial images by reconstruction of the space frequency components. Optical systems for implementing this type of process are also described.
    Type: Grant
    Filed: March 2, 2000
    Date of Patent: June 21, 2005
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.
    Inventors: Rainer Heintzmann, Christoph Cremer