Patents by Inventor Rainer K. Zawadzki

Rainer K. Zawadzki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable porfimer sodium compositions and methods for their manufacture
    Patent number: 5438071
    Abstract: A storage stable porfimer sodium (polyhematoporphyrin ether/ester) composition useful in the photodynamic therapy of cancer and other conditions is provided. The composition is characterized in that the percentage of ester linked porphyrin oligomers is less than 10% of the composition. Improved processes for preparing such compositions are also provided wherein acetylated hematoporphyrin is treated with alkali for sufficient time and temperature to reduce the amount of porphyrin oligomers joined by ester linkages to less than 10% of the composition.
    Type: Grant
    Filed: June 10, 1993
    Date of Patent: August 1, 1995
    Assignee: American Cyanamid Company
    Inventors: Steven L. Clauss, Michael J. Pastel, Rainer K. Zawadzki
  • Stable porfimer sodium compositions and methods for their manufacture
    Patent number: 5244914
    Abstract: A storage stable porfimer sodium (polyhematoporphyrin ether/ester) composition useful in the photodynamic therapy of cancer and other conditions is provided. The composition is characterized in that the percentage of ester linked porphyrin oligomers is less than 10% of the composition. Improved processes for preparing such compositions are also provided wherein acetylated hematoporphyrin is treated with alkali for sufficient time and temperature to reduce the amount of porphyrin oligomers joined by ester linkages to less than 10% of the composition.
    Type: Grant
    Filed: April 27, 1992
    Date of Patent: September 14, 1993
    Assignee: American Cyanamid Company
    Inventors: Steven L. Clauss, Michael J. Pastel, Rainer K. Zawadzki
  • N-Denitration of N,2,6-trinitroanilines with phase transfer catalysts
    Patent number: 4391992
    Abstract: A method for the N-denitration of secondary N,2,6-trinitroanilines with phase transfer catalysts.
    Type: Grant
    Filed: October 8, 1980
    Date of Patent: July 5, 1983
    Assignee: American Cyanamid Company
    Inventors: William A. Daniels, Rainer K. Zawadzki