Patents by Inventor Rainer Klocke

Rainer Klocke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cytoplasmic dynein heavy chain 1 genes, expression products, non-human animal model uses in human neurological diseases
    Publication number: 20070010657
    Abstract: A non-human animal model is provided, particularly a mouse model for movement hyperactivity, excitoxicity disorders (e.g. myoclonic cramping) and neurodegeneration, in which modified cytoplasmic dynein heavy chain1 is expressed. Modified human and mouse cytoplasmic dynein heavy chain1 proteins and nucleic adds are also provided, including the corresponding recombinant proteins. The invention further provides uses for the non-human animal model and the modified cytoplasmic dynein heavy chain1 proteins and nucleic acids, in particular for the diagnosis and treatment of medical conditions associated with over-expression of cytoplasmic dynein heavy chain1.
    Type: Application
    Filed: September 11, 2003
    Publication date: January 11, 2007
    Inventors: Rainer Klocke, Andreas Marquardt, Gisela Peraus, Gabriele Stumm, Philipp Wabnitz