Patents by Inventor Rainer NIKOLAY

Rainer NIKOLAY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screening for inhibitors of ribosome biogenesis
    Patent number: 9708602
    Abstract: The invention relates to a method and a prokaryotic cell for identifying a compound, which interferes with ribosome biogenesis, assembly and/or degradation. The cell expresses a first fusion protein comprising a first ribosomal protein, an amino acid linker and a first fluorescent protein, and a second fusion protein comprising a second ribosomal protein, an amino acid linker and a second fluorescent protein. The invention further relates to a gene construct comprising a first element encoding a first ribosomal protein fused to a first fluorescent protein by an amino acid linker, and a second element encoding a second ribosomal protein fused to a second fluorescent protein by an amino acid linker.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: July 18, 2017
    Assignee: UNIVERSITAET KONSTANZ
    Inventors: Rainer Nikolay, Elke Deuerling
  • SCREENING FOR INHIBITORS OF RIBOSOME BIOGENESIS
    Publication number: 20160122749
    Abstract: The invention relates to a method and a prokaryotic cell for identifying a compound, which interferes with ribosome biogenesis, assembly and/or degradation. The cell expresses a first fusion protein comprising a first ribosomal protein, an amino acid linker and a first fluorescent protein, and a second fusion protein comprising a second ribosomal protein, an amino acid linker and a second fluorescent protein. The invention further relates to a gene construct comprising a first element encoding a first ribosomal protein fused to a first fluorescent protein by an amino acid linker, and a second element encoding a second ribosomal protein fused to a second fluorescent protein by an amino acid linker.
    Type: Application
    Filed: July 9, 2014
    Publication date: May 5, 2016
    Inventors: Rainer NIKOLAY, Elke DEUERLING