Patents by Inventor Rainer Philippson

Rainer Philippson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-Androsten-3-ones and process for the preparation thereof
    Patent number: 4118488
    Abstract: 4-Androsten-3-ones of the formula ##STR1## wherein R.sub.1 is hydrogen or the acyl radical of an organic or inorganic acid, R.sub.2 is hydrogen, alkyl, or the acyl radical of an organic or inorganic acid, R.sub.3 is methyl or ethyl, R.sub.4 is hydrogen or methyl, ##STR2## and R.sub.5 is lower alkyl, have diuretic activity.
    Type: Grant
    Filed: March 3, 1977
    Date of Patent: October 3, 1978
    Assignee: Schering Aktiengesellschaft
    Inventors: Rainer Philippson, Bernhard Krieger, Jorge Casals-Stenzel, Ulrich Kerb, Wolfgang Losert, Klaus Prezewowsky, Rudolf Wiechert, Dieter Bittler
  • Process for the preparation of a .DELTA..sup.4 -3-keto steroid 17-propiolactone
    Patent number: 3966714
    Abstract: 4-Androstene-3,17-dione and 1,4-androstadiene-3,17-dione are converted to 3-(17.beta.-hydroxy-4-androsten-3-on-17.alpha.-yl)-propionic acid lactone in three steps by reaction with propargyl alcohol in the presence of an alkali alcoholate of a tertiary alcohol, hydrogenating the thus-produced 17.alpha.-(3-hydroxy-propinyl)-17-.beta.-hydroxy compound with hydrogen in the presence of a complex metallic catalyst to produce 17.alpha.-(3-hydroxypropyl)-17.beta.-hydroxy-3-keto-androst-4-ene, which is oxidized with chromic acid to the desired lactone.
    Type: Grant
    Filed: May 23, 1974
    Date of Patent: June 29, 1976
    Assignee: Schering Aktiengesellschaft
    Inventor: Rainer Philippson
  • Process for the preparation of steroid oxiranes
    Patent number: 3931154
    Abstract: Steroids containing both an isolated and an .alpha.,.beta.-unsaturated keto group are selectively reacted with dimethyl sulfonium methylide in a non-reactive polar solvent and in the presence of an alkali tertiary alcoholate to produce .alpha.,.beta.
    Type: Grant
    Filed: July 2, 1974
    Date of Patent: January 6, 1976
    Assignee: Schering Aktiengesellschaft
    Inventor: Rainer Philippson