Patents by Inventor Rainer Saffrich

Rainer Saffrich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9752985
    Abstract: For the combinatorial synthesis of molecule libraries, substances are embedded in a matrix consisting of a first solvent thereby forming transport units in a solid state of aggregation at a temperature of less than 90° C. and wherein after application to a support, the physical environment of the transport units is modified by the application of a physical process such as a laser printer whereby the substances in the transport units are linked to the support.
    Type: Grant
    Filed: June 13, 2001
    Date of Patent: September 5, 2017
    Assignees: DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS, EUROPÄISCHES LABORATORIUM FÜR MOLEKULARBIOLOGIE
    Inventors: Annemarie Poustka, Frank Breitling, Karl-Heinz Gross, Stefan Dübel, Rainer Saffrich
  • Publication number: 20160040120
    Abstract: The present invention relates to a three-dimensional (3D) model of a hematopoietic stem and progenitor cell (HSPC) niche, that comprises the coculture of human HSPC and human mesenchymal stromal cells in a defined 3D environment and thereby procures vital stem cell functions.
    Type: Application
    Filed: August 10, 2015
    Publication date: February 11, 2016
    Inventors: Eric Gottwald, Stefan Giselbrecht, Patrick Wuchter, Rainer Saffrich
  • Publication number: 20020008871
    Abstract: According to the method for detecting optical properties, especially luminescence reactions and refraction behavior of molecules which are directly or indirectly bound on a support, electromagnetic waves, especially laser light, are radiated onto the support. The light that is emitted or refracted by the molecules is then detected by a detector. The detector and the support are moved in relation to each other during and after the radiation of the electromagnetic waves. The support used is especially a transparent support with integrated position markings which can be detected by a detector, especially an optoelectronic scanning system. At least one of the integrated position markings is selected while the support and the detector are being moved in relation to each other or thereafter so that the light that is detected by the detector can be associated with a location on the support.
    Type: Application
    Filed: June 13, 2001
    Publication date: January 24, 2002
    Inventors: Annemarie Poustka, Frank Breitling, Karl-Heinz Gross, Stefan Dubel, Rainer Saffrich
  • Publication number: 20020006672
    Abstract: According to the inventive method for applying substances to a support, especially monomers for the combinatorial synthesis of molecule libraries, the substances are first embedded in a matrix consisting of at least one solvent, said solvent being in a solid state of aggregation at a temperature below 90° C., preferably below 50° C. The substances that are embedded in the matrix from transport units which are subsequently applied to the support in a solid state of aggregation, at a temperature below 90° C., preferably below 50° C. Alternatively, the transport units can be dissolved with a second solvent part and applied to the support in a liquid state of aggregation, where they adopt a solid or gel-like stage of aggregation after said solvent part has completely or partially evaporated. The substances on the matrix are then mobilized by modifying their physical environment and brought into the vicinity of the support surface through a physical process.
    Type: Application
    Filed: June 13, 2001
    Publication date: January 17, 2002
    Inventors: Annemarie Poustka, Frank Breitling, Karl-Heinz Gross, Stefan Dubel, Rainer Saffrich