Patents by Inventor Rainer Schlecker

Rainer Schlecker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5654310
    Abstract: Triazolopyrimidines of the formula ##STR1## where A, D and X have the meanings stated in the description, and their preparation are described. The novel compounds are suitable for controlling diseases.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: August 5, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Hans-Joerg Treiber, Berthold Behl, Hans Peter Hofmann
  • Patent number: 5631261
    Abstract: Novel triazoloquinazolines of the formula I ##STR1## where A, X R.sup.1 and R.sup.2 have the meanings stated in the description, and their preparation are described. The compounds are suitable for controlling diseases.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: May 20, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Hans-Joerg Treiber, Berthold Behl, Hans P. Hofmann
  • Patent number: 5622953
    Abstract: This invention relates to 1-amino-3-phenoxy-propane-derivatives of formula 1: ##STR1## (in which A, B, R, R.sup.x, X and Z are defined as in the specification described) and methods for their preparation.These compounds may be used as modulators of multidrug resistance in cancer chemotherapy and for circumvention of resistance in the treatment of malaria.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: April 22, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernd Janssen, Andreas Kling, Stefan Mueller, Kurt Ritter, Rainer Schlecker, Gerhard Keilhauer, Cynthia Romerdahl, Ulrich Traugott
  • Patent number: 5612344
    Abstract: The use of triazoloquinazolines for the production of drugs for controlling central nervous disorders is described. The triazoloquinazolines have the formula ##STR1## where R.sup.1, R.sup.2 and X have the meanings stated in the description.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: March 18, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Hans-J org Treiber, Berthold Behl, Hans P. Hofmann
  • Patent number: 5424330
    Abstract: Benzofurancarboxamides having basic substituents, of the formula I ##STR1## in which R.sup.1 and X have the meanings stated in the description, a process for the preparation thereof, and therapeutic agents containing them.
    Type: Grant
    Filed: May 24, 1994
    Date of Patent: June 13, 1995
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Hans-Juergen Teschendorf, Liliane Unger
  • Patent number: 5356901
    Abstract: Benzofurancarboxamides having basic substituents, of the formula I ##STR1## in which R.sup.1 and X have the meanings stated in the description, a process for the preparation thereof, and therapeutic agents containing them.
    Type: Grant
    Filed: February 16, 1993
    Date of Patent: October 18, 1994
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Hans-Juergen Teschendorf, Liliane Unger
  • Patent number: 5264452
    Abstract: A benzofurancarboxamide of the formula: ##STR1## where: X is hydrogen or methoxy,R.sup.1 is a radical of the formula: ##STR2## wherein R.sup.3 to R.sub.5 are each, independently of one another, hydrogen or C.sub.1-6 alkyl, R.sup.6 is a branched or unbranched C.sub.1-6 alkyl, or benzyl which may be methyl- or halogen-substituted on the nucleus, and is a single or double bond.
    Type: Grant
    Filed: June 25, 1992
    Date of Patent: November 23, 1993
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Hans-Juergen Teschendorf, Liliane Unger
  • Patent number: 5214047
    Abstract: A tetracyclic quinazoline derivative of the formula I: ##STR1## wherein A is C.sub.2-3 -alkylene or C.sub.2-3 -alkylene which is substituted by one or two C.sub.1-4 -alkyl radicals or A is cyclohexylene; X is phenyl, naphthyl or phenyl or naphthyl which is substituted by halogen, nitro, amino, C.sub.1-4 -alkylamino, sulfonylamino, C.sub.1-4 -acylamino, hydroxyl, C.sub.1-4 -alkoxy, --O--(CH.sub.2).sub.2-4 --NR.sup.1 R.sup.2, C.sub.1-4 -alkyl or C.sub.1-4 -alkylsulfonyl, wherein R.sup.1 and R.sup.2 are each hydrogen or C.sub.1-4 -alkyl; or X is thienyl or thienyl which is substituted by chlorine, fluorine, methyl, ethyl, methoxy, ethoxy, nitro or hydroxyl; and R is hydrogen, halogen, nitro, amino, C.sub.1-4 -alkylamino, sulfonylamino, C.sub.1-4 -acylamino, hydroxyl, C.sub.1-4 -alkoxy, --O--(CH.sub.2).sub.2-4 --NR.sup.3 R.sup.4, C.sub.1-4 -alkyl or C.sub.1-4 -alkylsulfonyl, wherein R.sup.3 and R.sup.4 are each hydrogen or C.sub.1-4 -alkyl, and the pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: September 12, 1988
    Date of Patent: May 25, 1993
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernd Ostersehlt, Rainer Schlecker, Beatrice Rendenbach, Gerda von Philipsborn, Albrecht Franke, deceased
  • Patent number: 5153228
    Abstract: 9-Amino-2-phenylbicyclo-[3.3.1]nonanes and 9-amino-2-phenylbicyclo[3.3.1]non-2-enes of the formula I ##STR1## where R.sup.1 and R.sup.2 are identical or different and each is hydrogen, halogen, alkyl, alkoxy, dialkylamino, trifluoromethyl, hydroxyl, alkylthio, alkylsulfonyl or nitro, R.sup.3 and R.sup.4 are identical or different and each is hydrogen, alkyl or 1 to 5 or alkenyl or alkynyl of 2 to 5 carbon atoms, or benzyl, it also being possible for R.sup.3 and R.sup.4 together to form a saturated chain which contains from three to seven carbon atoms and can be substituted by phenyl, and where is a single or double bond, are used for producing drugs which act, in particular, on the central nervous system.
    Type: Grant
    Filed: June 11, 1991
    Date of Patent: October 6, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Hans P. Hofmann, Laszlo Szabo
  • Patent number: 5151437
    Abstract: A benzofurancarboxamide of the formula: ##STR1## where: X is hydrogen or methoxy,R.sup.1 is a radical of the formula: ##STR2## wherein R.sup.3 to R.sup.5 are each, independently of one another, hydrogen or C.sub.1-6 alkyl, R.sup.6 is a branched or unbranched C.sub.1-6 alkyl, or benzyl which may be methyl- or halogen-substituted on the nucleus, and is a single or double bond.
    Type: Grant
    Filed: October 15, 1990
    Date of Patent: September 29, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Hans-Juergen Teschendorf, Liliane Unger
  • Patent number: 5039701
    Abstract: Benzofuran derivatives of the formula I ##STR1## where R.sup.1 to R.sup.5 and X have the meanings stated in the description, and therapeutic agents containing these derivatives.
    Type: Grant
    Filed: August 19, 1988
    Date of Patent: August 13, 1991
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Manfred Raschack, Josef Gries
  • Patent number: 4945114
    Abstract: Therapeutic agents containing enantiomers of propafenone, the preparation of the said agents and their use for certain groups of patients.
    Type: Grant
    Filed: July 29, 1988
    Date of Patent: July 31, 1990
    Assignee: BASF Aktiengesellschaft
    Inventors: Albrecht Franke, deceased, Rainer Schlecker, Josef Gries, Gerda Von Philipsborn, Liliane Unger
  • Patent number: 4845096
    Abstract: Benzofuran derivatives of the general formula I ##STR1## where R.sup.1 and R.sup.2 are each hydrogen, alkyl or phenylalkyl, where alkyl in each case is of 1 to 4 carbon atoms, R.sup.3 and R.sup.4 are identical or different and are each hydrogen or C.sub.1 -C.sub.4 -alkyl or together form a 3-membered to 5-membered chain which may be interrupted by an oxygen atom or an NR.sup.1 group, X is --CO--CH.dbd.CH--, --CO--CH.sub.2 --CH.sub.2 --or --CHOH--CH.sub.2 --CH.sub.2 --, n is 2 or 3 and Het is an aromatic 5-membered or 6-membered ring which contains a hetero atom from the group consisting of N, O and S and may additionally contain a (further) N atom, in which the ring may be substituted by C.sub.1 -C.sub.4 -alkyl, fluorine, chlorine, bromine, NH.sub.2 or NR.sup.1 R.sup.2, where R.sup.1 and R.sup.2 have the abovementioned meanings, the use of these benzofuran derivatives for the preparation of pharmaceutical, in particular antiulcerogenic, agents, and these agents themselves are described.
    Type: Grant
    Filed: March 18, 1988
    Date of Patent: July 4, 1989
    Assignee: BASF Aktiengsellschaft
    Inventors: Rainer Schlecker, Klaus Ruebsamen
  • Patent number: 4820821
    Abstract: Novel 1-phenyl-4(1H)-pyridazinone-imines of the formula (I) ##STR1## which are substituted at the imine nitrogen, and their addition salts with a physiologically tolerated acid, processes for their preparation, pharmaceutical formulations containing these compounds, and their use as drugs, in particular as antidepressants, antiparkinson drugs and antihypotonic agents.
    Type: Grant
    Filed: April 17, 1987
    Date of Patent: April 11, 1989
    Assignee: BASF Aktiengesellschaft
    Inventors: Rudolf Kropp, Marco Thyes, Rainer Schlecker, Albrecht Franke, Franz Reicheneder, Dora I. Reicheneder, August Amann, Hans-Juergen Teschendorf, Rolf Kretzschmar, Martin Traut, Josef Gries
  • Patent number: 4618622
    Abstract: Sulfonates of hydroxycoumarins of the formula I ##STR1## where R.sup.1 and R.sup.2 are identical or different and are each hydrogen, halogen or alkyl of 1 to 5 carbon atoms which can be substituted by --NR.sup.4 R.sup.5, --OR.sup.4 or --OC(O)R.sup.4, where R.sup.4 and R.sup.5 are identical or different and are each hydrogen or alkyl of 1 to 4 carbon atoms, or R.sup.1 and R.sup.2 are each a carboxylic acid group --OC(O)R.sup.4 or a carboxamido radical, with the proviso that R.sup.1 is not methyl when R.sup.2 is hydrogen, or R.sup.1 and R.sup.2 together form a --(CH.sub.2).sub.n -- chain where n is 3-5, and R.sup.3 is a straight-chain or branched alkyl radical of 1 to 8 carbon atoms or cycloalkyl of 3 to 8 carbon atoms, each of which can be substituted by halogen, --OR.sup.4, --NR.sup.4 R.sup.5, --CN or phenyl, or R.sup.3 is a straight-chain or branched alkenyl radical of 3 to 8 carbon atoms, an amino group -- NR.sup.4 R.sup.
    Type: Grant
    Filed: November 17, 1983
    Date of Patent: October 21, 1986
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Peter Schmidt, Peter C. Thieme, Dieter Lenke, Hans-Jurgen Teschendorf, Martin Traut, Claus D. Mueller, Hans P. Hofmann, Horst Kreiskott
  • Patent number: 4517196
    Abstract: Thiazolyloxamic acids and their derivatives of the general formula I ##STR1## processes for their preparation, and pharmaceutical formulations which contain these compounds and are useful as drugs for treating allergic disorders.
    Type: Grant
    Filed: August 26, 1982
    Date of Patent: May 14, 1985
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Ludwig Friedrich, Dieter Lenke
  • Patent number: 4463007
    Abstract: 1,2,4-Triazolo[1,5-c]-quinazolinones of the general formula I ##STR1## and their pharmaceutically tolerated salts, processes for their preparation and pharmaceutical formulations which contain these compounds and are useful drugs in the treatment of allergic disorders.
    Type: Grant
    Filed: November 15, 1982
    Date of Patent: July 31, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Ludwig Friedrich, Dieter Lenke