Patents by Inventor Rainuka Gupta
Rainuka Gupta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240019435Abstract: The present invention provides biological molecules for use in detecting, identifying and/or removing microbes and microbial components; diagnostic, therapeutic and filtration devices comprising the biological molecules; and systems and methods for treating fluids using the biological molecules and devices of the invention.Type: ApplicationFiled: September 24, 2021Publication date: January 18, 2024Applicant: MIRAKI INNOVATION THINK TANK LLCInventors: Nisha Veronica VARMA, Keith CRAWFORD, Gregory T. MARTIN, Goossen Jan Bernard BOER, Rainuka GUPTA, Zhiqian ZHOU, Christopher VELIS, Andrew D. CONNERTY
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Publication number: 20230285186Abstract: Compositions, systems and methods are provided for the treatment of subcutaneous brown or beige fat or visceral brown or beige fat, wherein the compositions comprise a cold solution comprising liquid water and/or ice particles, and optionally one or more additives and/or pharmacologic agents. The treatment of subcutaneous or visceral brown or beige fat provides activation of brown adipocytes, proliferation of brown adipocytes, increased volume of brown adipocytes, differentiation of precursors into beige and/or brown adipocytes, activation of beige adipocytes, stimulation of beige adipocytes and/or cryolipolysis of white adipocytes. The methods of treatment result in increased metabolic health, weight loss, and improved health.Type: ApplicationFiled: August 6, 2021Publication date: September 14, 2023Applicant: MIRAKI INNOVATION THINK TANK LLCInventors: Emilia JAVORSKY, Rainuka GUPTA, Karen E. MILLER, Tarik CHAUDHRY
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Publication number: 20230270927Abstract: The present invention provides biological molecules for use in detecting, identifying and/or removing microbes and microbial components; diagnostic, therapeutic and filtration devices comprising the biological molecules; and systems and methods for treating fluids using the biological molecules and devices of the invention.Type: ApplicationFiled: December 23, 2020Publication date: August 31, 2023Applicant: Miraki Innovation Think Tank LLCInventors: Nisha Veronica VARMA, Keith CRAWFORD, Gregory T. MARTIN, Goossen Jan Bernard BOER, Rainuka GUPTA, Zhiqian ZHOU, Christopher VELIS, Andrew D. CONNERTY
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Publication number: 20230046673Abstract: The present invention provides a cold solution and method for treating obstructive sleep apnea. The cold solution can comprise liquid and/or solid ice particles. In one embodiment, the method comprises delivering a cold solution to target tissue where the target tissue can be fat tissue located in one or more of an airway, a neck, a thorax, a diaphragm, a face, or an abdomen.Type: ApplicationFiled: December 21, 2020Publication date: February 16, 2023Applicant: MIRAKI INNOVATION THINK TANK LLCInventors: Christopher VELIS, Karen E. MILLER, Emilia JAVORSKY, Rainuka GUPTA, Tarik CHAUDHRY
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Publication number: 20230031549Abstract: A substantially solid solution is provided, which includes water and optionally one or more additives, wherein about 71% to about 100% of the water by volume is in a solid state. The substantially solid solution may be administered to a subcutaneous fat layer of a subject, in order to reduce or remove adipocytes through freezing. The substantially solid solution may be generated in a mold, or at a point of delivery, and may be administered by any suitable device or administered directly to a treatment site via an incision.Type: ApplicationFiled: December 18, 2020Publication date: February 2, 2023Applicant: MIRAKI INNOVATION THINK TANK LLCInventors: Christopher VELIS, Karen E. MILLER, Emilia JAVORSKY, Rainuka GUPTA, Tarik CHAUDHRY
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Publication number: 20230028322Abstract: The present invention provides a cold solution and method for inducing therapeutic hypothermia. The cold solution can comprise liquid and/or solid ice particles.Type: ApplicationFiled: December 28, 2020Publication date: January 26, 2023Applicant: MIRAKI INNOVATION THINK TANK LLCInventors: Christopher VELIS, Karen E. MILLER, Emilia JAVORSKY, Rainuka GUPTA, Tarik CHAUDHRY
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Publication number: 20220008110Abstract: A slurry is injected into a subject at a treatment site selected from the group consisting of (i) a deep subcutaneous fat layer, (ii) a superficial subcutaneous fat layer, and (iii) the deep subcutaneous fat layer and the superficial subcutaneous fat layer. Fat cells in the selected treatment site are ablated by the slurry. For example, the slurry is injected into (i) the deep subcutaneous fat layer only, (ii) the superficial subcutaneous fat layer only, (iii) the deep subcutaneous fat layer followed by the superficial subcutaneous fat layer, (iv) the superficial subcutaneous fat layer followed by the deep subcutaneous fat layer, or (v) the deep subcutaneous fat layer and the superficial subcutaneous fat layer simultaneously.Type: ApplicationFiled: October 4, 2019Publication date: January 13, 2022Applicant: MIRAKI INNOVATION THINK TANK LLCInventors: Christopher VELIS, Karen MILLER, Tarik S. CHAUDHRY, Emilia JAVORSKY, Rainuka GUPTA
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Publication number: 20210386580Abstract: Methods and systems for generating sterile slurry are provided. The slurry may be injected into subcutaneous fat of a subject to facilitate weight reduction or improve cosmetic appearances. Systems for generating a slurry comprise a repository for receiving a solution, a generator for generating the slurry from the solution, and a port for transferring the slurry from the system. Methods for generating a slurry comprise receiving a solution in a slurry generator, and generating slurry from the solution, wherein the slurry comprises ice particles capable of flowing through a cannula. Systems include continuous flow systems, agitated systems, and hybrid continuous flow and agitation systems.Type: ApplicationFiled: October 10, 2019Publication date: December 16, 2021Applicant: MIRAKI INNOVATION THINK TANK LLCInventors: Christopher VELIS, Tarik S. CHAUDHRY, Karen MILLER, William Roger MAINWARING-BURTON, Bradley Leo GUERTIN, Avi Aaron KURLANTZICK, Andrew Arthur DAVENPORT, Nicholas Robert TOSTA, Bryan Ellis WAGENKNECHT, Rainuka GUPTA
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Publication number: 20210346192Abstract: Systems and methods for generating slurry for injection are provided. Systems comprise a container and a device. The container comprises a solution for administration via an injection needle of a predetermined size. The device is capable of receiving the solution and producing a slurry having ice particles capable of flowing through the injection needle. Methods comprise selecting a container having the solution, receiving the solution in the device, and producing, in the device, the slurry having ice particles capable of flowing through the injection needle.Type: ApplicationFiled: October 10, 2019Publication date: November 11, 2021Applicant: MIRAKI INNOVATION THINK TANK LLCInventors: Christopher VELIS, Karen MILLER, Rainuka GUPTA, William Roger MAINWARING-BURTON, Bradley Leo GUERTIN, Avi Aaron KURLANTZICK, Andrew Arthur DAVENPORT, Nicholas Robert TOSTA, Bryan Ellis WAGENKNECHT
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Publication number: 20150151120Abstract: In an exemplary embodiment, a drug delivery device for driving an electrotransport current through a body surface of a user is provided. The device includes a patch with two electrodes and one or more reservoirs storing a therapeutic agent. The one or more reservoirs release the therapeutic agent into the body surface of the user when the reservoirs are positioned over the electrodes to form an electrical path for the electrotransport current. The device includes a controller which controls a controllable power supply to drive the electrotransport current through the body surface of the user in a predetermined profile.Type: ApplicationFiled: February 5, 2015Publication date: June 4, 2015Inventors: David Saar, Bogdan Mariusz Baudis, Rainuka Gupta, Vaishali Vilas Kamat, Matthew Kent Reich, Rajagopalan Srinivasan
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Patent number: 8983594Abstract: In an exemplary embodiment, a drug delivery device for driving an electrotransport current through a body surface of a user is provided. The device includes a patch with two electrodes and one or more reservoirs storing a therapeutic agent. The one or more reservoirs release the therapeutic agent into the body surface of the user when the reservoirs are positioned over the electrodes to form an electrical path for the electrotransport current. The device includes a controller which controls a controllable power supply to drive the electrotransport current through the body surface of the user in a predetermined profile.Type: GrantFiled: December 29, 2009Date of Patent: March 17, 2015Assignee: NuPathe, Inc.Inventors: David Saar, Bogdan Mariusz Baudis, Rainuka Gupta, Vaishali Vilas Kamat, Matthew Kent Reich, Rajagopalan Srinivasan
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Patent number: 8968382Abstract: A device comprising a single closed loop of elastic filament configurable between (i) a first configuration for movement along a blood vessel; and (ii) a second configuration for lodging within a blood vessel, the second configuration providing a single flow-restricting face sized and configured to cover the mouth of the aneurysm and obstruct blood flow to the aneurysm while permitting substantially normal blood flow through the blood vessel, with the degree of obstruction at the mouth of the aneurysm being such that the aneurysm thromboses when the face is positioned over the aneurysm, the flow-restricting face comprising a plurality of lengths of the closed loop of filament disposed in close proximity to one another in a switchback configuration, and at least one leg for holding the flow-restricting face adjacent the mouth of the aneurysm, the leg configured so as to maintain substantially normal blood flow through the blood vessel.Type: GrantFiled: October 9, 2012Date of Patent: March 3, 2015Assignee: Cornell UniversityInventors: Howard Riina, Jeffrey Milsom, J. Frederick Cornhill, Kevin Thomas Smith, Tuan Anh Nguyen, Darren Schneider, Christopher Dillon, Gabriel Greeley, Rainuka Gupta, Jeremy Van Hill, Leslie Johnston, Matthew DeNardo, Rahul Sathe
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Publication number: 20100262066Abstract: In an exemplary embodiment, a drug delivery device for driving an electrotransport current through a body surface of a user is provided. The device includes a patch with two electrodes and one or more reservoirs storing a therapeutic agent. The one or more reservoirs release the therapeutic agent into the body surface of the user when the reservoirs are positioned over the electrodes to form an electrical path for the electrotransport current. The device includes a controller which controls a controllable power supply to drive the electrotransport current through the body surface of the user in a predetermined profile.Type: ApplicationFiled: December 29, 2009Publication date: October 14, 2010Applicant: NuPathe, Inc.Inventors: David Saar, Bogdan Mariusz Baudis, Rainuka Gupta, Vaishali Vilas Kamat, Matthew Kent Reich, Rajagopalan Srinivasan
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Patent number: 7771381Abstract: A locking assembly is provided to simply and effectively prevent any unintentional adjustment of the adjustable valve mechanism in a fluid flow control device, without compromising the function of the device. The locking assembly generally includes at least one gripping arm for frictionally engaging at least a portion of the adjustable valve mechanism, and an actuating mechanism for controlling the deployment and release of the gripping arm. The locking assembly prevents unintentional adjustments that can adversely affect the pressure settings of the fluid flow control device. In particular, the locking assembly prevents unintentional adjustment, such as may be caused by the presence of a strong external magnetic field. The locking assembly can be easily disengaged, such as through the application or removal of an external mechanical force, to allow a clinician to adjust the pressure settings of the fluid flow control device as necessary.Type: GrantFiled: February 12, 2008Date of Patent: August 10, 2010Assignee: Codman & Shurtleff Inc.Inventors: Daniel McCusker, Alan J. Dextradeur, Rainuka Gupta, Carleton Bryan Southworth
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Patent number: 7736312Abstract: An acoustic monitoring system that is able to verify the success or failure of the positional adjustment of a valve without the need for additional energy during non-invasive reprogramming is provided. The acoustic monitoring system includes a programmer for generating a sequence of commands to adjust the valve mechanism, and for receiving acoustic signals for analysis, a transmitter to implement the command and adjust the valve, and a sensor for detecting an acoustic signal generated from the valve during execution of the commands. A method for using the acoustic monitoring system is also provided.Type: GrantFiled: January 22, 2004Date of Patent: June 15, 2010Assignee: Codman & Shurtleff, Inc.Inventors: Terri K. Taylor, Meir Rosenberg, Rainuka Gupta, Stephen Ferrer Wilson, Pierre S. Ostiguy, Bertil Romner, Alan J. Dextradeur
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Patent number: 7390310Abstract: A locking assembly is provided to simply and effectively prevent any unintentional adjustment of the adjustable valve mechanism in a fluid flow control device, without compromising the function of the device. The locking assembly generally includes at least one gripping arm for frictionally engaging at least a portion of the adjustable valve mechanism, and an actuating mechanism for controlling the deployment and release of the gripping arm. The locking assembly prevents unintentional adjustments that can adversely affect the pressure settings of the fluid flow control device. In particular, the locking assembly prevents unintentional adjustment, such as may be caused by the presence of a strong external magnetic field. The locking assembly can be easily disengaged, such as through the application or removal of an external mechanical force, to allow a clinician to adjust the pressure settings of the fluid flow control device as necessary.Type: GrantFiled: July 10, 2002Date of Patent: June 24, 2008Assignee: Codman & Shurtleff, Inc.Inventors: Daniel McCusker, Alan J. Dextradeur, Rainuka Gupta, Carleton Bryan Southworth
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Publication number: 20080127689Abstract: A locking assembly is provided to simply and effectively prevent any unintentional adjustment of the adjustable valve mechanism in a fluid flow control device, without compromising the function of the device. The locking assembly generally includes at least one gripping arm for frictionally engaging at least a portion of the adjustable valve mechanism, and an actuating mechanism for controlling the deployment and release of the gripping arm. The locking assembly prevents unintentional adjustments that can adversely affect the pressure settings of the fluid flow control device. In particular, the locking assembly prevents unintentional adjustment, such as may be caused by the presence of a strong external magnetic field. The locking assembly can be easily disengaged, such as through the application or removal of an external mechanical force, to allow a clinician to adjust the pressure settings of the fluid flow control device as necessary.Type: ApplicationFiled: February 12, 2008Publication date: June 5, 2008Applicant: Codman & Shurtleff, Inc.Inventors: Daniel McCusker, Alan J. Dextradeur, Rainuka Gupta, Carleton Bryan Southworth
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Patent number: 7094214Abstract: A shunt has a housing and a base. The base has a first set of electrodes extending across the base. A catheter is connected to the housing. The catheter has a longitudinal length, a proximal end, and a distal end. The catheter has a second set of electrodes extending along the longitudinal length of the catheter. At least two of the electrodes of said first set are electrically connected to two of the electrodes of the second set. The housing including a self sealing, needle penetrable outer housing wall. The system includes a probe assembly that is selectively penetratable through an outer housing wall.Type: GrantFiled: June 27, 2003Date of Patent: August 22, 2006Assignee: Codman & Shurtleff, Inc.Inventors: Alan J. Dextradeur, Terri Kelcourse Taylor, Rainuka Gupta
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Patent number: 7040485Abstract: A package for a drug-device combination product includes an outer package including a first gas impermeable sheet and a second gas impermeable sheet hermetically sealed there to on three sides. A gas permeable header is attached to an unsealed side of the first sheet and sealed to the second sheet on two sides. The first and second gas impermeable sheets and the header form an interior and an opening communicating with the interior. A gas permeable inner package is disposed within the outer package. A product is sealed within the inner package. The inner package is placed within the outer package and a top end of the header is sealed to the second sheet. The outer package is then sealed by sealing the first gas impermeable sheet to the second gas impermeable sheet at a seal point below the point where the header attaches to the first sheet.Type: GrantFiled: July 1, 2005Date of Patent: May 9, 2006Assignee: Codman & Shurtleff, Inc.Inventors: Rainuka Gupta, Alan J. Dextradeur
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Patent number: 6996952Abstract: A package for a drug-device combination product includes an outer package including a first gas impermeable sheet and a second gas impermeable sheet hermetically sealed there to on three sides. A gas permeable header is attached to an unsealed side of the first sheet and sealed to the second sheet on two sides. The first and second gas impermeable sheets and the header form an interior and an opening communicating with the interior. A gas permeable inner package is disposed within the outer package. A product is sealed within the inner package. The inner package is placed within the outer package and a top end of the header is sealed to the second sheet. The outer package is then sealed by sealing the first gas impermeable sheet to the second gas impermeable sheet at a seal point below the point where the header attaches to the first sheet.Type: GrantFiled: September 30, 2003Date of Patent: February 14, 2006Assignee: Codman & Shurtleff, Inc.Inventors: Rainuka Gupta, Alan J. Dextradeur