Patents by Inventor Raj B. Parekh

Raj B. Parekh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligosaccharide sequencing
    Patent number: 5100778
    Abstract: A method of oligosaccharide sequencing in which the components are determined essentially simultaneously is disclosed which comprises a series of steps as follows:A. Placing an identifying label on the reducing terminal residue of the oligosaccharide to be sequenced,B. Dividing said oligosaccharide into a plurality of separate portions of known integer amounts,C. Treating each said portion with a different reagent mix to thereby provide a series of reaction mixtures,D. Pooling known integer amounts of the products from each separate reaction mixture to give a product pool,E. Performing an analysis on said product pool which measures the molar proportions of the reaction products, andF. Reconstructing or identifying the starting oligosaccharide from the molar prevalence of said reaction products.
    Type: Grant
    Filed: October 3, 1989
    Date of Patent: March 31, 1992
    Assignee: Monsanto Company
    Inventors: Thomas W. Rademacher, Mark R. Wormald, Raj B. Parekh, Christopher J. Edge, Raymond A. Dwek
  • Tissue plasminogen activator from normal human colon cells
    Patent number: 4927630
    Abstract: Normal human colon fibroblast tissue plasminogen activator is separated by lysine-Sepharose affinity chromatography into Types I and II glycoforms and characterized with respect to the relative incidence of each type of oligosaccharide comprising the respective Types I and II glycoforms.
    Type: Grant
    Filed: March 11, 1988
    Date of Patent: May 22, 1990
    Assignee: Monsanto Company
    Inventors: Joseph Feder, Susan C. Howard, Arthur J. Wittwer, Thomas W. Rademacher, Raj B. Parekh, Raymond A. Dwek
  • Tissue plasminogen activator oligosaccharide from normal human colon cells
    Patent number: 4851517
    Abstract: Glycosylated plasminogen activator (t-PA) having a glycosylation pattern significantly different than exhibited by t-PA from Bowes melanoma cells is obtained from cultured normal human colon fibroblast cells (CCD-18Co).
    Type: Grant
    Filed: February 24, 1988
    Date of Patent: July 25, 1989
    Assignee: Monsanto Company
    Inventors: Joseph Feder, William R. Tolbert, Thomas W. Rademacher, Raj B. Parekh, Raymond A. Dwek
  • Tissue plasminogen activator from normal human colon cells
    Patent number: 4751084
    Abstract: Glycosylated plasminogen activator (t-PA) having a glycosylation pattern significantly different than exhibited by t-PA from Bowes melanoma cells is obtained from cultured normal human colon fibroblast cells (CCD-18Co).
    Type: Grant
    Filed: November 12, 1986
    Date of Patent: June 14, 1988
    Assignee: Monsanto Company
    Inventors: Joseph Feder, William R. Tolbert, Thomas W. Rademacher, Raj B. Parekh, Raymond A. Dwek
  • Oligosaccharide sequencing
    Patent number: RE35417
    Abstract: A method of oligosaccharide sequencing in which the components are determined essentially simultaneously is disclosed which comprises a series of steps as follows:A. Placing an identifying label on the reducing terminal residue of the oligosaccharide to be sequenced,B. Dividing said oligosaccharide into a plurality of separate portions of known integer amounts,C. Treating each said portion with a different reagent mix to thereby provide a series of reaction mixtures,D. Pooling known integer amounts of the products from each separate reaction mixture to give a product pool,E. Performing an analysis on said product pool which measures the molar proportions of the reaction products, andF. Reconstructing or identifying the starting oligosaccharide from the molar prevalence of said reaction products.
    Type: Grant
    Filed: March 24, 1994
    Date of Patent: December 31, 1996
    Assignee: Oxford GlycoSystems Ltd.
    Inventors: Thomas W. Rademacher, Mark R. Wormald, Raj. B. Parekh, Christopher J. Edge, Raymond A. Dwek