Patents by Inventor Raja C. Mugasimangalam

Raja C. Mugasimangalam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sequence specific and sequence non-specific methods and materials for cDNA normalization and subtraction
    Patent number: 6544741
    Abstract: This invention provides methods for constructing a normalized cDNA library, constructing a low copy gene library, preparing a probe from a biological sample and a kit for constructing a normalized cDNA library.
    Type: Grant
    Filed: July 12, 2000
    Date of Patent: April 8, 2003
    Assignee: Quark Biotech, Inc.
    Inventor: Raja C. Mugasimangalam
  • Sequence-dependent gene sorting techniques
    Patent number: 6468749
    Abstract: This invention provides a method of sorting genes comprising: (1) preparing ds cDNA molecules from mRNA molecules (2) digesting the ds cDNA molecules (3) ligating to the digested cDNA molecules a set of dsDNA oligonucleotide adaptors; (4) amplifying the ligated cDNA molecules; and (5) sorting the amplified cDNA molecules into nonoverlapping groups. This invention also provides two additional methods of sorting genes. This invention further provides a method of making sub-libraries of ligation sets.
    Type: Grant
    Filed: March 30, 2000
    Date of Patent: October 22, 2002
    Assignee: Quark Biotech, Inc.
    Inventors: Levy Ulanovsky, Raja C. Mugasimangalam, Paz Einat, Dina Zezin-Sonkin, Shlomit Gilad