Patents by Inventor Raja SIVAMANI

Raja SIVAMANI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10172938
    Abstract: A responsive hydrogel-based material may be used as a carrier system for the in situ delivery of various cargo substances, including bioactive moieties. The hydrogel structure, which includes photodegradable and thioether moieties in its three dimensional network, enables finely tuned local release of cargo substances as a function of the in vivo tissue environment (e.g., enzyme concentration or reducing environment) and externally applied stimuli (e.g., light) by selective spatiotemporal hydrogel degradation.
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: January 8, 2019
    Assignees: University of Delaware, The Regents of the University of California
    Inventors: Kristi L. Kiick, April M. Kloxin, Prathamesh M. Kharkar, Raja Sivamani, Emanual Maverakis
  • Publication number: 20170258907
    Abstract: A responsive hydrogel-based material may be used as a carrier system for the in situ delivery of various cargo substances, including bioactive moieties. The hydrogel structure, which includes photodegradable and thioether moieties in its three dimensional network, enables finely tuned local release of cargo substances as a function of the in vivo tissue environment (e.g., enzyme concentration or reducing environment) and externally applied stimuli (e.g., light) by selective spatiotemporal hydrogel degradation.
    Type: Application
    Filed: April 28, 2015
    Publication date: September 14, 2017
    Applicant: University of Delaware
    Inventors: Kristi L. KIICK, April M. KLOXIN, Prathamesh M. KHARKAR, Raja SIVAMANI, Emanual MAVERAKIS