Patents by Inventor Rajarao KAKUTURU

Rajarao KAKUTURU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for detection of antibiotic resistant
    Patent number: 11708616
    Abstract: The present disclosure provides methods and materials for determining if antibiotic resistant H. pylori is present in a sample. The methods may comprise obtaining a threshold level of H. pylori DNA from the sample, amplifying a region of the H. pylori DNA to generate multiple copies of the region of the H. pylori DNA, sequencing the multiple copies of the region of the H. pylori DNA, comparing sequences of multiple copies of the region of the H. pylori DNA to a reference sequence, identifying the presence of a mutation in multiple copies of the region of the H. pylori DNA, and determining a number of the multiple copies of the region of the H. pylori DNA with the mutation, wherein antibiotic resistant H. pylori is present in the sample when the number of the multiple copies of the region of the H. pylori DNA with the mutation is above a predetermined amount.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: July 25, 2023
    Assignee: AMERICAN MOLECULAR LABORATORIES INC.
    Inventors: Hongjun Zhang, Yi Zhou, Rajarao Kakuturu
  • METHODS FOR DETECTING A LEVEL OF H. PYLORI IN A FECAL SAMPLE
    Publication number: 20220235400
    Abstract: The present disclosure provides methods and materials for detecting a level of H. pylori in a sample.
    Type: Application
    Filed: May 26, 2020
    Publication date: July 28, 2022
    Inventors: Yi ZHOU, Hongjun ZHANG, Rajarao KAKUTURU, Zhaozhong CHONG
  • METHODS FOR DETECTION OF RARE DNA SEQUENCES IN FECAL SAMPLES
    Publication number: 20220235404
    Abstract: The disclosure provides methods and materials for identifying a low copy number DNA sequence in a fecal sample, such as a low copy number DNA sequence from a pathogenic bacterial species or genetic variant associated with disease.
    Type: Application
    Filed: May 26, 2020
    Publication date: July 28, 2022
    Inventors: Hongjun ZHANG, Yi ZHOU, Rajarao KAKUTURU, Zhaozhong CHONG
  • METHODS FOR DETECTION OF ANTIBIOTIC RESISTANT H.PYLORI
    Publication number: 20200399685
    Abstract: The present disclosure provides methods and materials for determining if antibiotic resistant H. pylori is present in a sample. The methods may comprise obtaining a threshold level of H. pylori DNA from the sample, amplifying a region of the H. pylori DNA to generate multiple copies of the region of the H. pylori DNA, sequencing the multiple copies of the region of the H. pylori DNA, comparing sequences of multiple copies of the region of the H. pylori DNA to a reference sequence, identifying the presence of a mutation in multiple copies of the region of the H. pylori DNA, and determining a number of the multiple copies of the region of the H. pylori DNA with the mutation, wherein antibiotic resistant H. pylori is present in the sample when the number of the multiple copies of the region of the H. pylori DNA with the mutation is above a predetermined amount.
    Type: Application
    Filed: November 16, 2018
    Publication date: December 24, 2020
    Inventors: Hongjun ZHANG, Yi ZHOU, Rajarao KAKUTURU