Patents by Inventor Rajeev D. Gokhale

Rajeev D. Gokhale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Micronized eplerenone compositions
    Patent number: 7157101
    Abstract: The invention relates to oral pharmaceutical compositions useful as aldosterone receptor blockers comprising the active agent micronized eplerenone in an amount of about 10 mg to about 1000 mg and one or more carrier materials.
    Type: Grant
    Filed: April 2, 2004
    Date of Patent: January 2, 2007
    Assignee: G.D. Searle, LLC
    Inventors: Shilpa S. Thosar, Rajeev D. Gokhale, Dwain S. Tolbert
  • Immediate release eplerenone compositions
    Patent number: 6863902
    Abstract: The invention relates to oral pharmaceutical compositions useful as aldosterone receptor blockers comprising the active agent micronized eplerenone in an amount of about 10 mg to about 1000 mg and one or more carrier materials.
    Type: Grant
    Filed: November 6, 2002
    Date of Patent: March 8, 2005
    Assignee: G. D. Searle & Co.
    Inventors: Shilpa S. Thosar, Rajeev D. Gokhale, Dwain S. Tolbert
  • Micronized eplerenone compositions
    Publication number: 20040192661
    Abstract: The invention relates to oral pharmaceutical compositions useful as aldosterone receptor blockers comprising the active agent micronized eplerenone in an amount of about 10 mg to about 1000 mg and one or more carrier materials.
    Type: Application
    Filed: April 2, 2004
    Publication date: September 30, 2004
    Applicant: G. D. Searle & Co.
    Inventors: Shilpa S. Thosar, Rajeev D. Gokhale, Dwain S. Tolbert
  • Immediate release eplerenone compositions
    Publication number: 20030215518
    Abstract: The invention relates to oral pharmaceutical compositions useful as aldosterone receptor blockers comprising the active agent micronized eplerenone in an amount of about 10 mg to about 1000 mg and one or more carrier materials.
    Type: Application
    Filed: November 6, 2002
    Publication date: November 20, 2003
    Inventors: Shilpa S. Thosar, Rajeev D. Gokhale, Dwain S. Tolbert
  • Nanoparticulate eplerenone compositions
    Publication number: 20030212053
    Abstract: There is provided a pharmaceutical composition comprising eplerenone in solid particulate form, wherein at least 90% of the eplerenone particles are smaller than about 15 &mgr;m, for example about 0.01 &mgr;m to about 1 &mgr;m, in diameter. The composition can be adapted for oral administration, for example as a tablet or capsule comprising eplerenone in a unit dosage amount of about 10 mg to about 1000 mg and one or more excipients.
    Type: Application
    Filed: April 16, 2003
    Publication date: November 13, 2003
    Inventors: Shilpa S. Thosar, Rajeev D. Gokhale, Subhash Desai, Dwain S. Tolbert
  • Controlled release eplerenone compositions
    Patent number: 6592902
    Abstract: The invention relates to oral pharmaceutical compositions useful as aldosterone receptor blockers comprising the active agent micronized eplerenone in an amount of about 10 mg to about 1000 mg and one or more carrier materials.
    Type: Grant
    Filed: January 31, 2002
    Date of Patent: July 15, 2003
    Inventors: Shilpa S. Thosar, Rajeev D. Gokhale, Dwain S. Tolbert
  • Immediate release eplerenone compositions
    Patent number: 6558707
    Abstract: The invention relates to oral pharmaceutical compositions useful as aldosterone receptor blockers comprising the active agent micronized eplerenone in an amount of about 10 mg to about 1000 mg and one or more carrier materials.
    Type: Grant
    Filed: March 19, 2002
    Date of Patent: May 6, 2003
    Assignee: G. D. Searle & Co.
    Inventors: Shilpa S. Thosar, Rajeev D. Gokhale, Dwain S. Tolbert
  • Immediate release eplerenone compositions
    Publication number: 20030072808
    Abstract: The invention relates to oral pharmaceutical compositions useful as aldosterone receptor blockers comprising the active agent micronized eplerenone in an amount of about 10 mg to about 1000 mg and one or more carrier materials.
    Type: Application
    Filed: March 19, 2002
    Publication date: April 17, 2003
    Inventors: Shilpa S. Thosar, Rajeev D. Gokhale, Dwain S. Tolbert
  • Immediate release eplerenone compositions
    Patent number: 6534093
    Abstract: The invention relates to oral pharmaceutical compositions useful as aldosterone receptor blockers comprising the active agent micronized eplerenone in an amount of about 10 mg to about 1000 mg and one or more carrier materials.
    Type: Grant
    Filed: March 19, 2002
    Date of Patent: March 18, 2003
    Assignee: G.D. Searle & Co.
    Inventors: Shilpa S. Thosar, Rajeev D. Gokhale, Dwain S. Tolbert
  • Eplerenone compositions having improved bioavailability
    Patent number: 6495165
    Abstract: The invention relates to oral pharmaceutical compositions useful as aldosterone receptor blockers comprising the active agent micronized eplerenone in an amount of about 10 mg to about 1000 mg and one or more carrier materials.
    Type: Grant
    Filed: March 19, 2002
    Date of Patent: December 17, 2002
    Assignee: G.D. Searle & Co.
    Inventors: Shilpa S. Thosar, Rajeev D. Gokhale, Dwain S. Tolbert
  • Controlled release eplerenone compositions
    Publication number: 20020136775
    Abstract: The invention relates to oral pharmaceutical compositions useful as aldosterone receptor blockers comprising the active agent micronized eplerenone in an amount of about 10 mg to about 1000 mg and one or more carrier materials.
    Type: Application
    Filed: January 31, 2002
    Publication date: September 26, 2002
    Inventors: Shilpa S. Thosar, Rajeev D. Gokhale, Dwain S. Tolbert
  • Immediate release eplerenone compositions
    Patent number: 6410054
    Abstract: The invention relates to oral pharmaceutical compositions useful as aldosterone receptor blockers comprising the active agent micronized eplerenone in an amount of about 10 mg to about 1000 mg and one or more carrier materials.
    Type: Grant
    Filed: December 8, 1999
    Date of Patent: June 25, 2002
    Assignee: G. D. Searle & Co.
    Inventors: Shilpa S. Thosar, Rajeev D. Gokhale, Dwain S. Tolbert
  • Nanoparticulate eplerenone compositions
    Publication number: 20020006919
    Abstract: There is provided a pharmaceutical composition comprising eplerenone in solid particulate form, wherein at least 90% of the eplerenone particles are smaller than about 15 &mgr;m, for example about 0.01 &mgr;m to about 1 &mgr;m, in diameter. The composition can be adapted for oral administration, for example as a tablet or capsule comprising eplerenone in a unit dosage amount of about 10 mg to about 1000 mg and one or more excipients.
    Type: Application
    Filed: December 7, 2000
    Publication date: January 17, 2002
    Inventors: Shilpa S. Thosar, Rajeev D. Gokhale, Subhash Desai, Dwain S. Tolbert
  • Single layer transdermal drug administration system
    Patent number: 5290561
    Abstract: A patch for the transdermal delivery of pharmaceutical drugs. The patch is characterized by having a single mass of elastomer in which the active drug and a percutaneous absorption enhancer are homogeneously dispersed throughout. The patch is especially well suited to delivering the beta.sub.2 adrenergic agonist drug albuterol.
    Type: Grant
    Filed: April 10, 1992
    Date of Patent: March 1, 1994
    Assignee: G. D. Searle & Co.
    Inventors: Bahram Farhadieh, Rajeev D. Gokhale
  • Single layer transdermal drug administration system
    Patent number: 5164189
    Abstract: A patch for the transdermal delivery of pharmaceutical drugs. The patch is characterized by having a single mass of elastomer in which the active drug and a percutaneous absorption enhancer are homogeneously dispersed throughout. The patch is especially well suited to delivering the beta.sub.2 adrenergic agonist drug albuterol.
    Type: Grant
    Filed: March 11, 1991
    Date of Patent: November 17, 1992
    Assignee: G. D. Searle & Co.
    Inventors: Bahram Farhadieh, Rajeev D. Gokhale, Hana Berger, Joseph Vallner