Patents by Inventor Rajeev Kumar Raveendran

Rajeev Kumar Raveendran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assay for detection of transient intracellular Ca
    Patent number: 9958462
    Abstract: This invention relates to a simple end point assay for detection of transient intracellular Ca2+ with broad applicability to many Ca2+ channel proteins comprising, Generation of expression constructs for the fusion proteins having the Ca2+/calmodulin dependent protein kinase II (CaMKII) phosphorylation sites of NR2A or NR2B subunits of N-methyl-D-aspartate receptor (NMDAR) or the voltage gated potassium channel of Drosophila (Eag) or any protein sequence which binds to the T-site of CaMKII similar to NR2B, conjugated to mitochondrial localizing signal sequence, or mutants of these sequences as described herein. Generation of mammalian expression constructs of ?-CaMKll as a chimera with green fluorescent protein (GFP-?-CaMKII) or its mutants as described herein.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: May 1, 2018
    Assignees: Rajiv Gandhi Centre for Biotechnology, Department of Biotechnology
    Inventors: Omkumar Vyomakesannair Ramakrishnapillai, Rajeev Kumar Raveendran, Mathew Steephan, Mayadevi Madhavan, Suma Priya Sudarsana Devi, Arunkumar Renganathan Chandrika, Archana Geetha Mohanan
  • Assay for Detection of Transient Intracellular CA2+
    Publication number: 20160320414
    Abstract: This invention relates to a simple end point assay for detection of transient intracellular Ca2+ with broad applicability to many Ca2+ channel proteins comprising, Generation of expression constructs for the fusion proteins having the Ca2+/calmodulin dependent protein kinase II (CaMKII) phosphorylation sites of NR2A or NR2B subunits of N-methyl-D-aspartate receptor (NMDAR) or the voltage gated potassium channel of Drosophila (Eag) or any protein sequence which binds to the T-site of CaMKII similar to NR2B, conjugated to mitochondrial localizing signal sequence, or mutants of these sequences as described herein. Generation of mammalian expression constructs of ?-CaMK11 as a chimera with green fluorescent protein (GFP-?-CaMKII) or its mutants as described herein.
    Type: Application
    Filed: May 5, 2016
    Publication date: November 3, 2016
    Inventors: Omkumar Vyomakesannair Ramakrishnapillai, Rajeev Kumar Raveendran, Mathew Steephan, Mayadevi Madhavan, Suma Priya Sudarsanadevi, Arunkumar Renganathan Chandrika, Archana Geetha Mohonan
  • Assay for Detection of Transient Intracellular CA2+
    Publication number: 20130089868
    Abstract: This invention relates to a simple end point assay for detection of transient intracellular Ca2+ with broad applicability to many Ca2+ channel proteins comprising, Generation of expression constructs for the fusion proteins having the Ca2+/calmodulin dependent protein kinase II (CaMKII) phosphorylation sites of NR2A or NR2B subunits of N-methyl-D-aspartate receptor (NMDAR) or the voltage gated potassium channel of Drosophila (Eag) or any protein sequence which binds to the T-site of CaMKII similar to NR2B, conjugated to mitochondrial localizing signal sequence, or mutants of these sequences as described herein. Generation of mammalian expression constructs of ?-CaMKll as a chimera with green fluorescent protein (GFP-?-CaMKII) or its mutants as described herein.
    Type: Application
    Filed: October 26, 2012
    Publication date: April 11, 2013
    Inventors: Omkumar Vyomakesannair Ramakrishnapillai, Rajeev Kumar Raveendran, Mathew Steephan, Mayadevi Madhaven, Suma Priya Sudarsanadevi, Arunkumar Renganathan Chandrika, Archana Geetha Mohanan
  • Assay for detection of transient intracellular CA
    Patent number: 8304198
    Abstract: This invention relates to a simple end point assay for detection of transient intracellular Ca2+ with broad applicability to many Ca2+ channel proteins comprising, Generation of expression constructs for the fusion proteins having the Ca2+/calmodulin dependent protein kinase II (CaMKII) phosphorylation sites of NR2A or NR2B subunits of N-methyl-D-aspartate receptor (NMDAR) or the voltage gated potassium channel of Drosophila (Eag) or any protein sequence which binds to the T-site of CaMKII similar to NR2B, conjugated to mitochondrial localizing signal sequence, or mutants of these sequences as described herein. Generation of mammalian expression constructs of ?-CaMKll as a chimera with green fluorescent protein (GFP-?-CaMKII) or its mutants as described herein.
    Type: Grant
    Filed: June 12, 2008
    Date of Patent: November 6, 2012
    Assignees: Rajiv Gandhi Centre for Biotechnology, Department of Biotechnology
    Inventors: Vyomakesannair Ramakrishnapillai Omkumar, Rajeev Kumar Raveendran, Mathew Steephan, Mayadevi Madhavan, Suma Priya Sudarsanadevi
  • Assay for Detection of Transient Intracellular CA2+
    Publication number: 20100240071
    Abstract: This invention relates to a simple end point assay for detection of transient intracellular Ca2+ with broad applicability to many Ca2+channel proteins comprising, Generation of expression constructs for the fusion proteins having the Ca2+/calmodulin dependent protein kinase II (CaMKII) phosphorylation sites of NR2A or NR2B subunits of N-methyl-D-aspartate receptor (NMDAR) or the voltage gated potassium channel of Drosophila (Eag) or any protein sequence which binds to the T-site of CaMKII similar to NR2B, conjugated to mitochondrial localizing signal sequence, or mutants of these sequences as described herein. Generation of mammalian expression constructs of ?-CaMKll as a chimera with green fluorescent protein (GFP-?-CaMKII) or its mutants as described herein.
    Type: Application
    Filed: June 12, 2008
    Publication date: September 23, 2010
    Applicants: RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY, DEPARTMENT OF BIOTECHNOLOGY
    Inventors: Vyomakesannair Omkumar Ramakrishnapillai, Rajeev Kumar Raveendran, Mathew Steephan, Mayadevi Madhavan, Suma Priya Sudarsanadevi