Abstract: The present invention relates to the use of one or more fumaric acid derivatives as NF-kappaB inhibitor. At the same time, the present invention relates to the use of the fumaric acid derivatives for preparing a pharmaceutical composition for treating diseases that may be influenced by NF-kappaB.

Abstract: A network of memory and coherence controllers is provided which interconnected nodes in a cache-coherent multi-processor system. The nodes contain multiple processors operatively connected via respective caches to associated memory and coherence controllers. The system supports better processor utilization and better application performance by reducing the latency in accessing data by performing proactive speculative data transfers. In being proactive, the system speculates, without specific requests from the processors, as to what data transfers will reduce the latency and will make data transfers according to information derived from the system at any time that data transfers could be made.

Abstract: The present invention relates to the use of fumaric acid amides of the general formula (I) 1

Abstract: An adaptive smoother includes a phase lock loop, a scintillation amplitude estimator and a fixed delay smoother operating on amplitude estimates for providing improved phase and/or code delay estimates of coherently modulated signals in the presence of dynamic phase process and time varying amplitudes. The adaptive smoother can be applied to GPS communication signals that are subject to fading due to small-scale temporal and spatial variations in ionospheric electron density. The adaptive smoother in a communication or navigation receiver results in improved signal tracking and navigation solutions.

Abstract: An integrated circuit having a memory which is reconfigurable as a main memory or as a cache. The integrated circuit may be a microprocessor chip with a memory that is reconfigurable to operate as an on-chip main memory or as an on-chip cache. Alternatively, the integrated circuit may be a stand-alone memory chip that is reconfigurable to operate as a main memory or as a cache.

Abstract: A system for automatic management of an e-service which partitions an e-service life-cycle among operational functionalities and non-operational functionalities and tends to the operational functionalities, thereby reducing the development burden of an e-service and enabling e-service owners to stay more focused on business related issues. In addition, a system according to the present teachings facilitates the smooth transition among the phases of an e-service life-cycle and facilitates the partition of system functionality into physically distributed components.

Abstract: A computer system is provided including a processor, a persistent storage device, and a main memory connected to the processor and the persistent storage device. The main memory includes a compressed cache for storing data retrieved from the persistent storage device after compression and an operating system. The operating system includes a plurality of interconnected software modules for accessing the persistent storage device and a filter driver interconnected between two of the plurality of software modules for managing memory capacity of the compressed cache and the buffer cache.

Abstract: A method and system for analysing software to estimate the cost of production, development and maintenance of computer applications. Unlike previous proposals for such analysis, where the primary measured parameters are the numbers of lines of code and function points, the inventive method identifies high complexity software segments arising from specific discontinuities in execution of the program, ie points at which the program has to, in effect, make decisions. These items are assigned complexity indices which may be summed to give an overall complexity value for the program or the indices may be displayed as a histogram showing the complexity distribution of the program.

Abstract: A remedial method (200) and apparatus (100) is described, by which unit information can be documented in a computer program. A set of user-supplied precompiler directives is added to the computer program that is to be converted, in which a preferred set of units, called primary units, are prescribed. A precompiler tool performs a conversion of a unit to its corresponding unit in the preferred set of units.

Abstract: A special-purpose appliance (SPA) works in conjunction with a server farm consisting of multiple caching server appliances (CSAs) to supervise a local storage medium (i.e., a shared cache) that is accessible by all the CSAs for storing at least some of the remote objects such as web pages and their embedded objects and/or streaming media objects that have been and/or will be served by one or more of the CSAs to its respective clients. The SPA preferably also determines when to prefetch remote objects such as web pages and their embedded objects and/or streaming media objects that are not currently stored in the shared cache, but which the SPA has determined are likely to be requested in the future by one or more of the CSAs one behalf of one or more of the CSA's respective clients.

Abstract: A method and apparatus for searching data to locate a portion identified by a search query. The data may comprise text files in a database. The search query comprises a sequence of two or more data fragments expected to be contained in the portion of data being sought. The method comprises receiving the data fragments and searching the data to locate the first fragment, then searching to find the location of the last. The method may include locating the earliest match between the data and the last data fragment which is preceded by matches between the data and each other fragment, the object being to find the shortest section of data which contains all the fragments in the right sequence and without overlapping one with another. The identified portion of text can be highlighted in a display of the data.

Abstract: A method and apparatus is described for the checking of the correctness and consistency of units and dimensions of variables and constants used in expressions, such as those used in computer programs. The present invention relates to a method (200) and apparatus (100) for performing such checking. A set of user-supplied precompiler directives is added to the computer program that is to be checked. Broadly, functions, function parameters, constants and variables are replaced with strings from the precompiler directives. The resulting expressions are reduced into a standard form. The expressions in the reduced form are tested for homogeneity according to a set of predetermined conditions.

Abstract: The present invention is directed to a powder coating composition that produces a low gloss coating upon cure. The powder coating composition includes one or more crosslinkable base polymer, a crosslinkable acrylic polymer and one or more free radical initiators. By adding spheroidal particles to the powder coating composition further reduction in gloss can be obtained while improving smoothness. These compositions are well suited to produce coatings on metallic substrates, such as automotive bodies and non-metallic substrates, such as reconstituted wood substrates, used for desk or table tops.

Abstract: A polyphase channelizer converts an intermediate frequency wideband signal into a complex signal that is sampled by parallel analog-to-digital converters having a bank of samplers respectively clocked by staggered clocking signals for respective converters for feeding I and Q quadrature samples to a polyphase filter bank of finite impulse response filters driving a fast Fourier transform processor for providing channelized digital signal outputs. The parallel analog-to-digital converters can operate at lower speeds but are parallel connected for effectively operating at required higher speeds. The channelizer channelizes the wideband signal using a polyphase clock for enabling high speed sampling and converting through low speed parallel analog to digital converters.

Abstract: The invention discloses a reusable heat pack comprising a soft sealed plastic bag containing a mixture of supercooled supersaturated recrystalizable solution of inorganic substance, alcohol, chemical compound additives, and means to trigger recrystallization of supercooled supersaturated recrystalizable solution of inorganic substance.

Abstract: A method of operating a data processing system having a main memory divided into memory pages that are swapped into and out of main memory when the main memory becomes short. The data processing system has an operating system that sends page store commands specifying memory pages to be stored in a swap file and page retrieve commands specifying memory pages to be retrieved from the swap file and stored in the main memory. The present invention provides a swap driver that utilizes compression code for converting one of the memory pages that is to be swapped out of main memory to a compressed memory page. The data processing memory includes a compressed page region that is used to store the compressed memory pages. A page table in the compressed page region specifies the location of each compressed page and the page address corresponding to that page.

Abstract: The present invention relates to the use of certain dialkyl fumarates for the preparation of pharmaceutical preparations for use in transplantation medicine or for the therapy of autoimmune diseases and said compositions in the form of micro-tablets or pellets. For this purpose, the dialkyl fumarates may also be used in combination with conventional preparations used in transplantation medicine and immunosuppressive agents, especially cyclosporines.

Abstract: In a compiler or program proving or verification software code, it is often useful to analyse a computer program and one way in which this might be partially achieved is by comparing algebraic expressions to see if they are equivalent, i.e. to see if they are derivable from a common template or function definition. Herein a string matching and replacement algorithm is used to compare two functions. Initially, each expression is converted to a “reduced” form by reference to a set of standard rules so as, for example, to ensure that terms comprising the same variables are combined. The variables names in each term are then replaced with symbols to produce, for each expression, a corresponding character string which, arranged in a predetermined order, are compared to determine equivalence of the expressions. To achieve this, a matrix M is formed with entries corresponding to the symbols and the matrix elements are incremented according to pre-set rules.

Abstract: The present invention relates to the use of certain dialkyl fumarates for the preparation of pharmaceutical preparations for use in transplantation medicine or for the therapy of autoimmune diseases and said compositions in the form of micro-tablets or pellets. For this purpose, the dialkyl fumarates may also be used in combination with conventional preparations used in transplantation medicine and immunosuppressive agents, especially cyclosporines.

Abstract: The present invention relates to the use of individual fumaric acid derivatives or mixtures thereof for preparing a pharmaceutical composition for treating mitochondrial diseases, especially for treating Parkinson's syndrome, Alzheimer's disease, Chorea Huntington disease, retinopathia pigmentosa and mitochondrial encephalomyopathy. Preferably, the fumaric acid derivative(s) is/are those selected from the group consisting of fumaric acid dialkyl esters or fumaric acid monoalkyl esters in the form of the free acid or a salt thereof.