Patents by Inventor Rajendra P. Tanpure

Rajendra P. Tanpure has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180291043
    Abstract: Benzocyclooctene (fused 6,8 ring system) analogues and corresponding indene (fused 6,5 ring system) analogues function as inhibitors of tubulin polymerization. The compounds are useful as anticancer agents in a new therapeutic approach for cancer treatment utilizing small-molecule inhibitors of tubulin polymerization that also act as vascular disrupting agents (VDAs).
    Type: Application
    Filed: June 8, 2018
    Publication date: October 11, 2018
    Applicant: BAYLOR UNIVERSITY
    Inventors: Kevin G. PINNEY, Christine A. HERDMAN, Rajendra P. TANPURE, Zhi CHEN
  • Publication number: 20180002355
    Abstract: Benzocyclooctene (fused 6,8 ring system) analogues and corresponding indene (fused 6,5 ring system) analogues function as inhibitors of tubulin polymerization. The compounds are useful as anticancer agents in a new therapeutic approach for cancer treatment utilizing small-molecule inhibitors of tubulin polymerization that also act as vascular disrupting agents (VDAs).
    Type: Application
    Filed: June 30, 2017
    Publication date: January 4, 2018
    Inventors: Kevin G. PINNEY, Christine A. HERDMAN, Rajendra P. TANPURE, Zhi CHEN
  • Publication number: 20120130129
    Abstract: The disclosed process can efficiently synthesize functionalized benzosuberenes. The process provides an improved method of production of benzosuberene and compounds containing a benzosuberene moiety, which is characterized by a ring closing methodology comprising reaction of a 5-phenylpentanoic acid with Eaton's reagent to form the benzosuberone. The process, optionally, further includes steps for adding a functional group at the ketone position.
    Type: Application
    Filed: November 16, 2011
    Publication date: May 24, 2012
    Applicant: BAYLOR UNIVERSITY
    Inventors: Kevin G. Pinney, Madhavi Sriram, Clinton George, Rajendra P. Tanpure