Patents by Inventor Rajendrakumar Reddy Gadikota

Rajendrakumar Reddy Gadikota has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of chirally purified substituted benzothiazole diamines
    Patent number: 10179774
    Abstract: Methods for preparing chirally purified substituted 4,5,6,7-tetrahydro-benzothiazole diamines such as, for example, (6R)2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole and purifying a dominant enantiomer of substituted 4,5,6,7-tetrahydro-benzothiazole diamines from entantiomerically enriched mixtures of substituted 4,5,6,7-tetrahydro-benzothiazole diamines are provided herein.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: January 15, 2019
    Assignee: Knopp Biosciences LLC
    Inventors: Prasad Raje, Rajendrakumar Reddy Gadikota, Jian-Xie Chen, Olga V. Lapina, John M. McCall
  • SYNTHESIS OF CHIRALLY PURIFIED SUBSTITUTED BENZOTHIAZOLE DIAMINES
    Publication number: 20170158649
    Abstract: Methods for preparing chirally purified substituted 4,5,6,7-tetrahydro-benzotiazole diamines such as, for example, (6R)2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole and purifying a dominant enantiomer of substituted 4,5,6,7-tetrahydro-benzotiazole diamines from entantiomerically enriched mixtures of substituted 4,5,6,7-tetrahydro-benzotiazole diamines are provided herein.
    Type: Application
    Filed: December 5, 2016
    Publication date: June 8, 2017
    Inventors: Prasad RAJE, Rajendrakumar Reddy GADIKOTA, Jian-Xie CHEN, Olga V. LAPINA, John M. McCALL
  • SYNTHESIS OF CHIRALLY PURIFIED SUBSTITUTED BENZOTHIAZOLE DIAMINES
    Publication number: 20140100372
    Abstract: Methods for preparing chirally purified substituted 4,5,6,7-tetrahydro-benzothiazole diamines such as, for example, (6R)2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole and purifying a dominant enantiomer of substituted 4,5,6,7-tetrahydro-benzothiazole diamines from entantiomerically enriched mixtures of substituted 4,5,6,7-tetrahydro-benzothiazole diamines are provided herein.
    Type: Application
    Filed: August 22, 2013
    Publication date: April 10, 2014
    Applicant: KNOPP NEUROSCIENCES, INC.
    Inventors: Prasad RAJE, Rajendrakumar Reddy GADIKOTA, Jian-Xie CHEN, Olga V. LAPINA, John M. McCALL
  • Synthesis of chirally purified substituted benzothiazole diamines
    Patent number: 8519148
    Abstract: Methods for preparing chirally purified substituted 4,5,6,7-tetrahydro-benzothiazole diamines such as, for example, (6R)2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole and purifying a dominant enantiomer of substituted 4,5,6,7-tetrahydro-benzothiazole diamines from entantiomerically enriched mixtures of substituted 4,5,6,7-tetrahydro-benzothiazole diamines are provided herein.
    Type: Grant
    Filed: March 14, 2008
    Date of Patent: August 27, 2013
    Assignee: Knopp Neurosciences, Inc.
    Inventors: Prasad Raje, Rajendrakumar Reddy Gadikota, Jian-Xie Chen, Olga V. Lapina, John M. McCall
  • Protected diols for prostaglandin synthesis
    Patent number: 7161042
    Abstract: A process for the preparation of prostaglandin compounds having the formula (I): wherein A is selected from the group consisting of C1–C6 alkyl groups; C7–C16 aralkyl groups wherein an aryl portion thereof is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6 alkyl groups, halo and CF3; and (CH2)nOR? wherein n is an integer from 1 to 3 and R? represents a C6–C10 aryl group which is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6 alkyl groups, halo and CF3; B is selected from OR? and NHR? wherein R? is C1–C6 alkyl groups; and represents a double bond or a single bond, is disclosed. Novel intermediates are also disclosed.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: January 9, 2007
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Derek Wyndham Clissold, Stuart Wilbert Craig, Rajendrakumar Reddy Gadikota, Min He, Jurjus Fayez Jurayj, Shahrokh Kazerani, Erwin Rannala, Pradeep Kumar Sharma
  • Protected and unprotected triols for prostaglandin synthesis
    Patent number: 7141706
    Abstract: A process for the preparation of prostaglandin compounds having the formula (I): wherein A is selected from the group consisting of C1–C6 alkyl groups; C7–C16 aralkyl groups wherein an aryl portion thereof is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6 alkyl groups, halo and CF3; and (CH2)nOR? wherein n is an integer from 1 to 3 and R? represents a C6–C10 aryl group which is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6 alkyl groups, halo and CF3; B is selected from OR? and NHR? wherein R? is C1–C6 alkyl groups; and represents a double bond or a single bond, is disclosed. Novel intermediates are also disclosed.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: November 28, 2006
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Derek Wyndham Clissold, Stuart Wilbert Craig, Rajendrakumar Reddy Gadikota, Min He, Jurjus Fayez Jurayj, Shahrokh Kazerani, Erwin Rannala, Pradeep Kumar Sharma
  • Prostaglandin synthesis
    Patent number: 7109371
    Abstract: A process for the preparation of prostaglandin compounds having the formula (I): wherein A is selected from the group consisting of C1–C6 alkyl groups; C7–C16 aralkyl groups wherein an aryl portion thereof is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6 alkyl groups, halo and CF3; and (CH2)nOR? wherein n is an integer from 1 to 3 and R? represents a C6–C10 aryl group which is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6 alkyl groups, halo and CF3; B is selected from OR? and NHR? wherein R? is C1–C6 alkyl groups; and represents a double bond or a single bond, is disclosed. Novel intermediates are also disclosed.
    Type: Grant
    Filed: January 5, 2004
    Date of Patent: September 19, 2006
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Derek Wyndham Clissold, Stuart Wilbert Craig, Rajendrakumar Reddy Gadikota, Min He, Jurjus Fayez Jurayj, Shahrokh Kazerani, Erwin Rannala, Pradeep Kumar Sharma