Patents by Inventor Rajendran Vairagoundar

Rajendran Vairagoundar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOMODULATING UREA AZALIDES
    Publication number: 20230390237
    Abstract: Defined herein are immunomodulating Formula (1) compounds wherein R, R0, R1, R2, R3 and W are as defined herein, stereoisomers thereof, and pharmaceutically acceptable salts thereof; and compositions comprising said compounds. The invention also includes methods for treating an inflammatory and/or immunological disease or disorder in an animal by administering a therapeutically effective amount of a Formula (1) compound, stereoisomer thereof, and a pharmaceutically acceptable salt thereof; or use of said compound of Formula (1) to prepare a medicament for treating an inflammatory and/or immunological disease or disorder in an animal.
    Type: Application
    Filed: August 17, 2023
    Publication date: December 7, 2023
    Inventors: Mark R. Cox, Timothy L. Stuk, Todd M. Maddux, Richard Andrew Ewin, Paul D. Johnson, Tomasz Respondek, Graham M. Kyne, Rajendran Vairagoundar
  • Endoparasitic depsipeptides
    Patent number: 11786575
    Abstract: The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.
    Type: Grant
    Filed: March 17, 2022
    Date of Patent: October 17, 2023
    Assignee: Zoetis Services LLC
    Inventors: Michael P. Curtis, Susan M. Sheehan, Graham M. Kyne, Matthew W. Bedore, Richard A. Ewin, Paul D. Johnson, Tom L. McTier, Christopher S Knauer, Rajendran Vairagoundar
  • Endoparasitic depsipeptides
    Patent number: 11771738
    Abstract: The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2 are as defined herein. The present invention also contemplates compositions, methods of treatment, and uses as a medicament to treat an animal for an endoparasitic infection with a Formula (1) compound.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: October 3, 2023
    Assignee: Zoetis Services LLC
    Inventors: Todd Maddux, Matthew W. Bedore, Paul D. Johnson, Tomasz Respondek, Susan M. K. Sheehan, Graham M. Kyne, Richard A. Ewin, Rajendran Vairagoundar, Michael P. Curtis
  • Immunomodulating urea azalides
    Patent number: 11771677
    Abstract: Defined herein are immunomodulating Formula (1) compounds wherein R, R0, R1, R2, R3 and W are as defined herein, stereoisomers thereof, and pharmaceutically acceptable salts thereof; and compositions comprising said compounds. The invention also includes methods for treating an inflammatory and/or immunological disease or disorder in an animal by administering a therapeutically effective amount of a Formula (1) compound, stereoisomer thereof, and a pharmaceutically acceptable salt thereof; or use of said compound of Formula (1) to prepare a medicament for treating an inflammatory and/or immunological disease or disorder in an animal.
    Type: Grant
    Filed: March 11, 2021
    Date of Patent: October 3, 2023
    Assignee: Zoetis Services LLC
    Inventors: Mark R. Cox, Timothy L. Stuk, Todd M. Maddux, Richard Andrew Ewin, Paul D. Johnson, Tomasz Respondek, Graham M. Kyne, Rajendran Vairagoundar
  • Endoparasitic Depsipeptides
    Publication number: 20220323540
    Abstract: The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2 are as defined herein. The present invention also contemplates compositions, methods of treatment, and uses as a medicament to treat an animal for an endoparasitic infection with a Formula (1) compound.
    Type: Application
    Filed: May 7, 2019
    Publication date: October 13, 2022
    Inventors: Todd Maddux, Matthew W. Bedore, Paul D. Johnson, Tomasz Respondek, Susan M.K. Sheehan, Graham M. Kyne, Richard A. Ewin, Rajendran Vairagoundar, Michael P. Curtis
  • Endoparasitic Depsipeptides
    Publication number: 20220211802
    Abstract: The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.
    Type: Application
    Filed: March 17, 2022
    Publication date: July 7, 2022
    Inventors: Michael P. Curtis, Susan M. Sheehan, Graham M. Kyne, Matthew W. Bedore, Richard A. Ewin, Paul D. Johnson, Tom L. McTier, Christopher S. Knauer, Rajendran Vairagoundar
  • Endoparasitic depsipeptides
    Patent number: 11331369
    Abstract: The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: May 17, 2022
    Assignee: Zoetis Services LLC
    Inventors: Michael P. Curtis, Susan M. Sheehan, Graham M. Kyne, Matthew W. Bedore, Richard A. Ewin, Paul D. Johnson, Tom L. McTier, Christoper S. Knauer, Rajendran Vairagoundar
  • IMMUNOMODULATING UREA AZALIDES
    Publication number: 20210290591
    Abstract: Defined herein are immunomodulating Formula (1) compounds wherein R, R0, R1, R2, R3 and W are as defined herein, stereoisomers thereof, and pharmaceutically acceptable salts thereof; and compositions comprising said compounds. The invention also includes methods for treating an inflammatory and/or immunological disease or disorder in an animal by administering a therapeutically effective amount of a Formula (1) compound, stereoisomer thereof, and a pharmaceutically acceptable salt thereof; or use of said compound of Formula (1) to prepare a medicament for treating an inflammatory and/or immunological disease or disorder in an animal.
    Type: Application
    Filed: March 11, 2021
    Publication date: September 23, 2021
    Inventors: Mark R. Cox, Timothy L. Stuk, Todd M. Maddux, Richard Andrew Ewin, Paul D. Johnson, Tomasz Respondek, Graham M. Kyne, Rajendran Vairagoundar
  • Endoparasitic Depsipeptides
    Publication number: 20200282016
    Abstract: The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.
    Type: Application
    Filed: November 28, 2018
    Publication date: September 10, 2020
    Inventors: Michael P. Curtis, Susan M. Sheehan, Graham M. Kyne, Matthew W. Bedore, Richard A. Ewin, Paul D. Johnson, Tom L. McTier, Christoper S. Knauer, Rajendran Vairagoundar
  • Phenicol antibacterial agents
    Patent number: 9422236
    Abstract: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical compositions containing these novel compounds, and methods for the preparation of these compounds.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: August 23, 2016
    Assignee: Zoetis Services LLC
    Inventors: Timothy Allan Johnson, Rajendran Vairagoundar, Richard Andrew Ewin
  • NOVEL PHENICOL ANTIBACTERIAL AGENTS
    Publication number: 20160075647
    Abstract: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical compositions containing these novel compounds, and methods for the preparation of these compounds.
    Type: Application
    Filed: April 16, 2014
    Publication date: March 17, 2016
    Inventors: Timothy Allan Johnson, Rajendran Vairagoundar, Richard Andrew Ewin
  • Phenicol antibacterial agents
    Patent number: 9206126
    Abstract: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of the compounds of formula I
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: December 8, 2015
    Assignee: Zoetis Services LLC
    Inventors: Richard Andrew Ewin, Timothy Allan Johnson, Susan Mary Kult Sheehan, Rajendran Vairagoundar
  • NOVEL PHENICOL ANTIBACTERIALS
    Publication number: 20150344412
    Abstract: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical compositions containing these novel compounds, and methods for the preparation of these compounds.
    Type: Application
    Filed: August 7, 2015
    Publication date: December 3, 2015
    Inventors: Brian A. Duclos, Richard Andrew Ewin, Paul D. Johnson, Timothy Allan Johnson, Graham M. Kyne, Derek James Sheehan, Susan Mary Kult Sheehan, Donald James Skalitzky, Rajendran Vairagoundar
  • Phenicol antibacterials
    Patent number: 9145355
    Abstract: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical compositions containing these novel compounds, and methods for the preparation of these compounds.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: September 29, 2015
    Assignee: Zoetis Services LLC
    Inventors: Brian A. Duclos, Richard Andrew Ewin, Paul D. Johnson, Timothy Allan Johnson, Graham M. Kyne, Derek James Sheehan, Susan Mary Kult Sheehan, Donald James Skalitzky, Rajendran Vairagoundar
  • PHENICOL ANTIBACTERIALS
    Publication number: 20150266910
    Abstract: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.
    Type: Application
    Filed: June 5, 2015
    Publication date: September 24, 2015
    Inventors: Michael Curtis, Brian A. Duclos, Richard A. Ewin, Paul D. Johnson, Timothy Allan Johnson, Rajendran Vairagoundar, Denis Billen, Richard M. Goodwin, Andrea K. Haber-Stuk, Graham M. Kyne, Susan M. K. Sheehan
  • MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
    Publication number: 20140343098
    Abstract: The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
    Type: Application
    Filed: April 10, 2014
    Publication date: November 20, 2014
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Urvi Sheth, Lev T.D. Fanning, Mehdi Michel Djamel Numa, Hayley Binch, Dennis Hurley, Jinglan Zhou, Sara S. Hadida Ruah, Anna Hazlewood, Alina Silina, Rajendran Vairagoundar, Fredrick Van Goor, Peter D.J. Grootenhuis, Martyn Botfield
  • NOVEL PHENICOL ANTIBACTERIALS
    Publication number: 20140303384
    Abstract: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical compositions containing these novel compounds, and methods for the preparation of these compounds.
    Type: Application
    Filed: October 5, 2012
    Publication date: October 9, 2014
    Inventors: Brian A. Duclos, Richard Andrew Ewin, Paul D. Johnson, Timothy Allan Johnson, Graham M. Kyne, Derek James Sheehan, Susan Mary Kult Sheehan, Donald James Skalitzky, Rajendran Vairagoundar
  • Tyrosine kinase inhibitors
    Patent number: 8815906
    Abstract: Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.
    Type: Grant
    Filed: March 18, 2009
    Date of Patent: August 26, 2014
    Assignee: Chembridge Corporation
    Inventors: Yahua Liu, Alexey Vyacheslavovich Anikin, Charles Chamchoumis Mikel, Douglas Eric McGrath, Goverdhan Reddy Vavilala, Jason Conrad Pickens, Aleksander Kadushkin, Luyong Jiang, Mohan Santhanam Thiruvazhi, Sergey Zozulya, Rajendran Vairagoundar, Tong Zhu, Alexander Chucholowski, Zheng Yan, Alisher Khasanov, Christina Gregor
  • Modulators of ATP-Binding Cassette transporters
    Patent number: 8802700
    Abstract: The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: August 12, 2014
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Urvi Sheth, Lev T. D. Fanning, Mehdi Numa, Hayley Binch, Dennis James Hurley, Jinglan Zhou, Sara S. Hadida Ruah, Anna R. Hazlewood, Alina Silina, Rajendran Vairagoundar, Fredrick F. Van Goor, Peter Diederik Jan Grootenhuis, Martyn C. Botfield
  • Cephalosporins useful as antibacterial agents
    Patent number: 8722656
    Abstract: The present invention provides novel cephalosporin derivatives of formula I, their analogues, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: May 13, 2014
    Assignee: Zoetis LLC
    Inventors: Brian A. Duclos, Edmund L. Ellsworth, Richard A. Ewin, Paul D. Johnson, Timothy A. Johnson, Graham M. Kyne, Susan M. K. Sheehan, Rajendran Vairagoundar