Abstract: The present disclosure provides novel compounds with activity as PPAR?/? and PPAR? dual agonists. The disclosure also provides methods of treating diabetes mellitus and methods of treating Alzheimer's disease utilizing the novel compounds, as well as pharmaceutical formulations comprising the novel compounds.

Abstract: An asset provider can identify a segment of a broadcast stream to be extracted at a distribution endpoint and formatted for on-demand viewing by cable subscribers. An asset provider can use a start time code and a stop time code to identify the start and end of the segment in the broadcast stream. The asset provider can also insert tags into the broadcast stream identifying a segment to be extracted at the distribution endpoint. Upon receiving the broadcast stream, the distribution endpoint can then extract the segment identified by either the start and stop time codes or the tags.